About Center for Translational Neuromedicine

Leadership

The heads of Center for Translational Neuromedicine are Professor Maiken Nedergaard and Professor Steve Goldman.

Steven Goldman

Professor Steve Goldman


Professor Steve Goldman is internationally recognized for his innovative work using glia progenitors to repair myelin in models of several demyelinating diseases, including MS.
Maiken Nedergaard

Professor Maiken Nedergaard


Professor Maiken Nedergaard is known around the world due to her recent research published in Science showing how sleep rids the brain of some of the proteins connected to dementia. 

New Approaches for Treating Neurological Diseases

Center for Translational Neuromedicine focuses on developing new approaches for investigating and treating neurological diseases, primarily using the tools of physiology and imaging coupled with cell and gene therapy. Our emphasis is on using these technologies to enable neural and glial cell replacement in the adult brain and spinal cord, as a means of both disease modeling and therapeutic repair. The two labs in the Center are Dr. Goldman’s Division of Cell and Gene Therapy with focus on neural stem cells and glial progenitor biology and the translational applications thereof, and Dr. Nedergaard’s Division of Glial Therapeutics that focuses on astrocytic physiology and pathology, as well as on cerebral blood flow and its glial regulation. Together, the labs are expanding the scope of glial biology, such that disorders long thought neuronal in nature are now being investigated as disorders principally of glial cells, including both astrocytes and oligodendrocytes as well as their progenitors.

Funding

The section is funded by the Novo Nordisk Foundation. The goal is to accelerate the process of bringing the newest research from the lab and into the treatment of patients.

Research Overview

Division of Cell and Gene Therapy (Goldman Lab)

Focus on cell replacement, tumorigenesis, and myelin disease

Division of Glial Therapeutics (Nedergaard Lab)

Focus on sleep, stroke and traumatic brain and spinal cord injury

Division of Neuron-Glia Circuitry (Hirase Lab)

Focus on the impacts of astrocytic signaling.