- Published
Zika Virus NS4A and NS4B Proteins Deregulate Akt-mTOR Signaling in Human Fetal Neural Stem Cells to Inhibit Neurogenesis and Induce Autophagy
Liang, Q., Luo, Z., Zeng, J., Chen, W., Foo, S., Lee, S., Ge, J., Wang, S., Goldman, Steven Alan, Zlokovic, B. V., Zhao, Z. & Jung, J. U., 3 Nov 2016, In: Cell Stem Cell. 19, 5, p. 663-671 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Young glial progenitor cells competitively replace aged and diseased human glia in the adult chimeric mouse brain
Vieira, R., Mariani, J. N., Huynh, N. P. T., Stephensen, Hans Jacob Teglbjærg, Solly, R., Tate, A., Schanz, S., Cotrupi, N., Mousaei, M., Sporring, Jon, Benraiss, A. & Goldman, Steven Alan, 2024, In: Nature Biotechnology. 42, p. 719-730 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Voluntary running enhances glymphatic influx in awake behaving, young mice
Holstein-Rønsbo, Stephanie, Petersen, Nicolas Caesar & Nedergaard, Maiken, 2018, In: Neuroscience Letters. 662, p. 253-258 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visual Evoked Potentials as an Early-Stage Biomarker in the rTg4510 Tauopathy Mouse Model
Parka, A., Volbracht, C., Hall, B., Bastlund, J. F., Nedergaard, Maiken, Laursen, B., Botta, P. & Sotty, F., 2023, In: Journal of Alzheimer's Disease. 93, 1, p. 247-262 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Versatile treadmill system for measuring locomotion and neural activity in head-fixed mice
Carlsen, Eva Maria Meier, Nedergaard, Maiken & Rasmussen, R. N., 2022, In: STAR Protocols. 3, 4, 14 p., 101701.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vascular dysfunction-The disregarded partner of Alzheimer's disease
Sweeney, M. D., Montagne, A., Sagare, A. P., Nation, D. A., Schneider, L. S., Chui, H. C., Harrington, M. G., Pa, J., Law, M., Wang, D. J. J., Jacobs, R. E., Doubal, F. N., Ramirez, J., Black, S. E., Nedergaard, M., Benveniste, H., Dichgans, M., Iadecola, C., Love, S., Bath, P. M. & 49 others, , 2019, In: Alzheimers & Dementia. 15, 1, p. 158-167Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Validation of ultrasonography for measurement of cartilage thickness in the equine carpus
Andersen, Camilla, Griffin, J. F., Jacobsen, Stine, Østergaard, Stine, Walters, M., Mori, Yuki & Lindegaard, Casper, 2022, In: Veterinary Radiology & Ultrasound. 63, 4, p. 478-489 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using crystallography tools to improve vaccine formulations
de Abreu Fantini, M. C., Pinto Oliveira, C. L., de Souza Lopes, J. L., Martins, T. D. S., Akamatsu, M. A., Trezena, A. G., Tino-De-Franco, M., Botosso, V. F., Brazil Esteves Sant'Anna, O. A., Kardjilov, N., Rasmussen, Martin Kaag & Nunes Bordallo, Heloisa, 1 Jan 2022, In: IUCrJ. 9, p. 11-20 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Using Fiber Photometry in Mice to Estimate Fluorescent Biosensor Levels During Sleep
Andersen, Mie, Tsopanidou, Anastasia, Radovanovic, Tessa, Compere, V. N., Hauglund, Natalie Linea, Nedergaard, Maiken & Kjærby, Celia, 2023, In: Bio-protocol. 13, 15, 17 p., e4734.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unravelling and Exploiting Astrocyte Dysfunction in Huntington's Disease
Khakh, B. S., Beaumont, V., Cachope, R., Munoz-Sanjuan, I., Goldman, Steven Alan & Grantyn, R., Jul 2017, In: Trends in Neurosciences. 40, 7, p. 422-437 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Understanding the role of the perivascular space in cerebral small vessel disease
Brown, R., Benveniste, H., Black, S. E., Charpak, S., Dichgans, M., Joutel, A., Nedergaard, Maiken, Smith, K. J., Zlokovic, B. V. & Wardlaw, J. M., 2018, In: Cardiovascular Research. 114, 11, p. 1462-1473 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Understanding the functions and relationships of the glymphatic system and meningeal lymphatics
Louveau, A., Plog, B. A., Antila, S., Alitalo, K., Nedergaard, Maiken & Kipnis, J., 1 Sep 2017, In: The Journal of Clinical Investigation. 127, 9, p. 3210-3219 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Uncovering the anatomical and molecular landscape of the developing entorhinal cortex.
Liu, Y., Bergmann, T. B., Peralvo Vidal, Juan Miguel, Lee, J., Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Gorodkin, Jan, Hyttel, P., Pers, Tune H, witter, M. & Hall, Vanessa Jane, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Ultrastructure of precapillary sphincters and the neurovascular unit
Grubb, Søren, 2023, In: Vascular Biology. 5, 1, 15 p., e230011.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twists and turns of ocular glymphatic clearance – new study reveals surprising findings in glaucoma
Rangroo Thrane, V., Hynnekleiv, L., Wang, X., Thrane, A. S., Krohn, J. & Nedergaard, Maiken, 2021, In: Acta Ophthalmologica. 99, 2, p. e283-e284 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Transplanted neural progenitors bridge gaps to benefit cord-injured monkeys
Goldman, Steven Alan, 2018, In: Nature Medicine. 24, 4, p. 388-390 3 p.Research output: Contribution to journal › Journal article › Communication
- Published
Translating cell therapies for neurodegenerative diseases: Huntington's disease as a model disorder
Rosser, A. E., Busse, M. E., Gray, W. P., Badin, R. A., Perrier, A. L., Wheelock, V., Cozzi, E., Martin, U. P., Salado-Manzano, C., Mills, L. J., Drew, C., Goldman, Steven Alan, Canals, J. M., Thompson, L. M. & SC4HD Members, S. M., 2022, In: Brain. 145, 5, p. 1584-1597 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Transient but not chronic hyperglycemia accelerates ocular glymphatic transport
Delle, Christine, Wang, X., Giannetto, M., Newbold, E., Peng, W., Gomolka, Ryszard Stefan, Ladrón-de-Guevara, A., Cankar, Neza, Nielsen, Elise Schiøler, Kjærby, Celia, Weikop, Pia, Mori, Yuki & Nedergaard, Maiken, 2024, In: Fluids and Barriers of the CNS. 21, 1, 13 p., 26.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement
Iwai, Y., Ozawa, K., Yahagi, K., Mishima, Tsuneko, Akther, S., Vo, C. T., Lee, Ashley Bomin, Tanaka, M., Itohara, S. & Hirase, Hajime, 2021, In: Frontiers in Neural Circuits. 15, 16 p., 658343.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcranial Direct Current Stimulation (tDCS Induces Adrenergic Receptor-Dependent Microglial Morphological Changes in Mice
Mishima, T., Nagai, T., Yahagi, K., Akther, S., Oe, Y., Monai, H., Kohsaka, S. & Hirase, Hajime, 2019, In: eNeuro. 6, 5, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The state of brain activity modulates cerebrospinal fluid transport
Miyakoshi, L. M., Stæger, Frederik Filip Vinggaard, Li, Q., Pan, C., Xie, L., Kang, H., Pavan, C., Dang, J., Sun, Q., Ertürk, A. & Nedergaard, Maiken, 2023, In: Progress in Neurobiology. 229, 11 p., 102512.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of glial pathology in Huntington's disease
Goldman, Steven Alan, 2024, Huntington's Disease: Pathogenic Mechanisms and Implications for Therapeutics. Elsevier, p. 337-351 15 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The role of central serotonergic markers and estradiol changes in perinatal mental health
Borgsted, C., Høgh, S., Høgsted, E. S., Fonnesbech-Sandberg, L., Ekelund, Kim, Albrechtsen, C. K., Wiis, J. T., Hegaard, Hanne Kristine, Cvetanovska, E., Juul, Anders, Frederiksen, H., Pinborg, Anja, Weikop, Pia & Frøkjær, Vibe Gedsø, 2022, In: Acta Psychiatrica Scandinavica. 146, 4, p. 357-369 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intrinsic effects of EIF2B mutations in human Vanishing White Matter-derived glial progenitor cells
Osorio, M. J., Lassen, Mette, Kristine, M. & Goldman, Steven Alan, 2019, In: Glia. 67, S1, p. E312-E313 2 p., T08-031A.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The homeostatic astroglia emerges from evolutionary specialization of neural cells
Verkhratsky, A. & Nedergaard, Maiken, 5 Aug 2016, In: Royal Society of London. Philosophical Transactions B. Biological Sciences. 371, 1700, p. 1-11 11 p., 20150428.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glymphatic system: reactive gliosis as a negative regulator
Nedergaard, Maiken, 2019, In: Glia. 67, S1, p. E91 1 p., S26-02.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The glymphatic system and Amyotrophic lateral sclerosis
Eisen, A., Nedergaard, Maiken, Gray, E. & Kiernan, M. C., 2024, In: Progress in Neurobiology. 234, 10 p., 102571.Research output: Contribution to journal › Review › Research › peer-review
- Published
The glymphatic system: implications for drugs for central nervous system diseases
Lohela, T. J., Lilius, T. O. & Nedergaard, Maiken, 2022, In: Nature Reviews Drug Discovery. 21, 10, p. 763-779 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glymphatic system: Current understanding and modeling
Bohr, T., Hjorth, P. G., Holst, S. C., Hrabětová, S., Kiviniemi, V., Lilius, T., Lundgaard, I., Mardal, K. A., Martens, E. A., Mori, Yuki, Nägerl, U. V., Nicholson, C., Tannenbaum, A., Thomas, J. H., Tithof, J., Benveniste, H., Iliff, J. J., Kelley, D. H. & Nedergaard, Maiken, 2022, In: iScience. 25, 9, 33 p., 104987.Research output: Contribution to journal › Review › Research › peer-review
- Published
The glymphatic system: A novel component of fundamental neurobiology
Hablitz, L. M. & Nedergaard, Maiken, 2021, In: Journal of Neuroscience. 41, 37, p. 7698-7711 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The glymphatic pathway in neurological disorders
Rasmussen, Martin Kaag, Mestre, H. & Nedergaard, Maiken, 2018, In: The Lancet Neurology. 17, 11, p. 1016-1024 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The endothelial border to health: Mechanistic evidence of the hyperglycemic culprit of inflammatory disease acceleration
Hansen, N. W., Hansen, A. J. & Sams, A., Mar 2017, In: IUBMB Life. 69, 3, p. 148-161 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The elusive varicose astrocytes
Rasmussen, R. N. & Smith, N. A., 2022, In: Trends in Neurosciences. 45, 2, p. 94-95 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
The effect of long-duration spaceflight on perivascular spaces within the brain
Wostyn, P., Mader, T. H., Gibson, C. R. & Nedergaard, Maiken, 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 32, 1 p., e2207724119.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The developmental neurogenic niche of the Entorhinal cortex revealed by single-cell transcriptomics.
Bergmann, T. B., Liu, Y., Lee, J., Peralvo Vidal, Juan Miguel, Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Gorodkin, Jan, Hall, Vanessa Jane & Pers, Tune H, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
The continued need for animals to advance brain research
Homberg, J. R., Adan, R. A. H., Alenina, N., Asiminas, A., Bader, M., Beckers, T., Begg, D. P., Blokland, A., Burger, M. E., van Dijk, G., Eisel, U. L. M., Elgersma, Y., Englitz, B., Fernandez-Ruiz, A., Fitzsimons, C. P., van Dam, A-M., Gass, P., Grandjean, J., Havekes, R., Henckens, M. J. A. G. & 54 others, , 2021, In: Neuron. 109, 15, p. 2374-2379 6 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
The association of anxiety and other clinical features with CACNA1C rs1006737 in patients with depression
Dam, H., Buch, J. O. D., Nielsen, A. B., Weikop, Pia & Jørgensen, Martin Balslev, 2022, In: Translational Neuroscience. 13, 1, p. 320-326 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis
Zeng, J., Dong, S., Luo, Z., Xie, X., Fu, B., Li, P., Liu, C., Yang, X., Chen, Y., Wang, X., Liu, Z., Wu, J., Yan, Y., Wang, F., Chen, J. F., Zhang, J., Long, G., Goldman, S. A., Li, S., Zhao, Z. & 1 others, , 1 Oct 2020, In: Cell Stem Cell. 27, 4, p. 618-632.e9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ser19Stop single nucleotide polymorphism (SNP) of human PHYHIPL affects the cerebellum in mice
Sugimoto, H., Horii, T., Hirota, J. N., Sano, Y., Shinoda, Y., Konno, A., Hirai, H., Ishizaki, Y., Hirase, Hajime, Hatada, I., Furuichi, T. & Sadakata, T., 2021, In: Molecular Brain. 14, 1, 9 p., 52.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ocular Glymphatic Clearance System
Wang, X., Lou, N., Eberhardt, A., Jørgensen, P. K., Xu, Q., Foerstera, B., Peng, S., Yang, Y., Shi, M., L R Xavier, Anna , Ertürk, A., Libby, R. T., Lu, C., Thrane, A. & Nedergaard, Maiken, 30 Dec 2019, bioRxiv, 23 p.Research output: Working paper › Preprint › Research
- Published
The Glymphatic System and Pain
Goldman, N., Hablitz, L. M., Mori, Yuki & Nedergaard, Maiken, 2020, In: Medical Acupuncture. 32, 6, p. 373-376 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Glymphatic System (En)during Inflammation
Mogensen, F. L., Delle, Christine & Nedergaard, Maiken, 2021, In: International Journal of Molecular Sciences. 22, 14, 20 p., 7491.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Effect of Hyperoxia on Central and Peripheral Factors of Arm Flexor Muscles Fatigue Following Maximal Ergometer Rowing in Men
Volianitis, S., Rasmussen, P., Petersen, Nicolas Caesar & Secher, Niels H., 2022, In: Frontiers in Physiology. 13, 10 p., 829097.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Concept of Neuroglia
Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 1-13 13 p. (Advances in Experimental Medicine and Biology, Vol. 1175).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The Chemogenetic Receptor Ligand Clozapine N-Oxide Induces in vivo Neuroreceptor Occupancy and Reduces Striatal Glutamate Levels
Bærentzen, S., Casado-Sainz, A., Lange, D., Shalgunov, Vladimir, Tejada, I. M., Xiong, M., L'Estrade, E. T., Edgar, F. G., Lee, H., Herth, Matthias Manfred & Palner, M., 2019, In: Frontiers in Neuroscience. 13, 7 p., 187.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Challenges of First-in-Human Stem Cell Clinical Trials: What Does This Mean for Ethics and Institutional Review Boards?
Barker, R. A., Carpenter, M. K., Forbes, S., Goldman, Steven Alan, Jamieson, C., Murry, C. E., Takahashi, J. & Weir, G., 8 May 2018, In: Stem Cell Reports. 10, 5, p. 1429-1431 3 p.Research output: Contribution to journal › Comment/debate › Communication
- Published
The Brain's Glymphatic System: Current Controversies
Mestre, H., Mori, Yuki & Nedergaard, Maiken, 2020, In: Trends in Neurosciences. 43, 7, p. 458-466 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Alzheimer's disease 5xFAD mouse model is best suited to investigate pretargeted imaging approaches beyond the blood-brain barrier
Lopes van den Broek, S. I., Sehlin, D., Andersen, Jens Velde, Aldana, Blanca, Beschorner, Natalie, Nedergaard, Maiken, Knudsen, Gitte Moos, Syvanen, S. & Herth, Matthias Manfred, 2023, In: Frontiers in Nuclear Medicine. 2, 7 p., 1001722.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Acute and Chronic Effects of Acetazolamide and Topiramate on Intracranial Pressure and CSF Secretion
Westgate, C., Kamp-Jensen, C., Israelsen, I., Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Jensen, C., Styrishave, Bjarne, MacAulay, Nanna, Jensen, Rasmus Herlo Beenfeldt & Eftekhari, S., 2022, In: Journal of Headache and Pain. 23, Suppl. 1, 1 p., P218.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Temporal Information Entropy of the Blood-Oxygenation Level-Dependent Signals Increases in the Activated Human Primary Visual Cortex
DiNuzzo, M., Mascali, D., Moraschi, M., Bussu, G., Maraviglia, B., Mangia, S. & Giove, F., Feb 2017, In: Frontiers in Physics. 5, p. 1-11 11 p., 7.Research output: Contribution to journal › Journal article › Research › peer-review
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SPECT imaging of the glymphatic pathway with In-111-labeled ovalbumin in the rat brain
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In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy
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Understanding the functions and relationships of the glymphatic system and meningeal lymphatics
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Remyelination in the Central Nervous System
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Glymphatic fluid transport is suppressed by the aquaporin-4 inhibitor AER-271
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The glymphatic system and Amyotrophic lateral sclerosis
Research output: Contribution to journal › Review › Research › peer-review