Center for Translational Neuromedicine

  1. Published

    Insulin-like growth factor 1 supplementation supports motor coordination and affects myelination in preterm pigs

    Christiansen, Line Iadsatian, Ventura, G. C., Holmqvist, B., Aasmul-Olsen, Karoline, Lindholm, S. E. H., Lycas, M. D., Mori, Yuki, Secher, Jan Bojsen-Møller, Burrin, D. G., Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2023, In: Frontiers in Neuroscience. 17, 15 p., 1205819.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Erratum: Two types of muscarinic acetylcholine receptors in Drosophila and other arthropods (Cellular and Molecular Life Sciences (2013) 70 (3231-3242) DOI: 10.1007/s0001801313340))

    Collin, C., Hauser, Frank, Gonzalez De Valdivia, E., Li, S., Reisenberger, J., Carlsen, Eva Maria Meier, Khan, Z., Hansen, N. O., Puhm, F., Søndergaard, Leif, Niemiec, J., Heninger, M., Ren, G. R. & Grimmelikhuijzen, Cornelis (Cok), Nov 2013, In: Cellular and Molecular Life Sciences. 70, 21, p. 4197 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  3. Published

    A Survey of Molecular Imaging of Opioid Receptors

    Cumming, P., Marton, J., Lilius, T. O., Olberg, D. E. & Rominger, A., 2019, In: Molecules. 24, 22, 35 p., 4190.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    The association of anxiety and other clinical features with CACNA1C rs1006737 in patients with depression

    Dam, H., Buch, J. O. D., Nielsen, A. B., Weikop, Pia & Jørgensen, Martin Balslev, 2022, In: Translational Neuroscience. 13, 1, p. 320-326 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Cerebrospinal fluid clearance in Alzheimer disease measured with dynamic PET

    De Leon, M. J., Li, Y., Okamura, N., Tsui, W. H., Saint-Louis, L. A., Glodzik, L., Osorio, R. S., Fortea, J., Butler, T., Pirraglia, E., Fossati, S., Kim, H. J., Carare, R. O., Nedergaard, Maiken, Benveniste, H. & Rusinek, H., 2017, In: Journal of Nuclear Medicine. 58, 9, p. 1471-1476 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Transient but not chronic hyperglycemia accelerates ocular glymphatic transport

    Delle, Christine, Wang, X., Giannetto, M., Newbold, E., Peng, W., Gomolka, Ryszard Stefan, Ladrón-de-Guevara, A., Cankar, Neza, Nielsen, Elise Schiøler, Kjærby, Celia, Weikop, Pia, Mori, Yuki & Nedergaard, Maiken, 2024, In: Fluids and Barriers of the CNS. 21, 1, 13 p., 26.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Long-term high-fat diet increases glymphatic activity in the hypothalamus in mice

    Delle, Christine, Cankar, Neza, Digebjerg Holgersson, C., Hvorup Knudsen, H., Nielsen, Elise Schiøler, Kjærby, Celia, Mori, Yuki, Nedergaard, Maiken & Weikop, Pia, 2023, In: Scientific Reports. 13, 1, 11 p., 4137.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. E-pub ahead of print

    Chronic sleep fragmentation impairs brain interstitial clearance in young wildtype mice

    Deng, Saiyue, Hu, Y., Chen, S., Xue, Yang, Yao, D., Sun, Q., Nedergaard, Maiken, Wang, W. & Ding, Fengfei, 2024, (E-pub ahead of print) In: Journal of Cerebral Blood Flow and Metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Computational Flux Balance Analysis Predicts that Stimulation of Energy Metabolism in Astrocytes and their Metabolic Interactions with Neurons Depend on Uptake of K(+) Rather than Glutamate

    DiNuzzo, M., Giove, F., Maraviglia, B. & Mangia, S., Jan 2017, In: Neurochemical Research. 42, 1, p. 202-16 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    State-Dependent Changes in Brain Glycogen Metabolism

    DiNuzzo, M., Walls, Anne Byriel, Öz, G., Seaquist, E. R., Waagepetersen, Helle S., Bak, Lasse Kristoffer, Nedergaard, Maiken & Schousboe, Arne, 2019, Brain Glycogen Metabolism. DiNuzzo, M. & Schousboe, A. (eds.). Springer, p. 269-309 41 p. (Advances in Neurobiology, Vol. 23).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  11. Published

    Temporal Information Entropy of the Blood-Oxygenation Level-Dependent Signals Increases in the Activated Human Primary Visual Cortex

    DiNuzzo, M., Mascali, D., Moraschi, M., Bussu, G., Maraviglia, B., Mangia, S. & Giove, F., Feb 2017, In: Frontiers in Physics. 5, p. 1-11 11 p., 7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Brain energetics during the sleep-wake cycle

    DiNuzzo, M. & Nedergaard, Maiken, Dec 2017, In: Current Opinion in Neurobiology. 47, p. 65-72 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Glial cells in schizophrenia: a unified hypothesis

    Dietz, Andrea Grostøl, Goldman, Steven Alan & Nedergaard, Maiken, 2020, In: Lancet Psychiatry. 7, 3, p. 272-281 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    Local extracellular K+ in cortex regulates norepinephrine levels, network state, and behavioral output

    Dietz, Andrea Grostøl, Weikop, Pia, Hauglund, Natalie Linea, Andersen, Mie, Petersen, Nicolas Caesar, Rose, Laura, Hirase, Hajime & Nedergaard, Maiken, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 40, 9 p., e2305071120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Changes in the composition of brain interstitial ions control the sleep-wake cycle

    Ding, F., O'Donnell, J., Xu, Q., Kang, N., Goldman, N. & Nedergaard, Maiken, 29 Apr 2016, In: Science. 352, 6285, p. 550-555 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Cerebrospinal fluid is a significant fluid source for anoxic cerebral oedema

    Du, T., Mestre, H., Kress, B. T., Liu, G., Sweeney, A. M., Samson, A. J., Rasmussen, M. K., Mortensen, K. N., Bork, P. A. R., Peng, W., Olveda, G. E., Bashford, L., Toro, E. R., Tithof, J., Kelley, D. H., Thomas, J. H., Hjorth, P. G., Martens, E. A., Mehta, R. I., Hirase, H. & 2 others, Mori, Yuki & Nedergaard, Maiken, 2022, In: Brain. 145, 2, p. 787–797 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Probing the polarity of spontaneous perisomatic GABAergic synaptic transmission in the mouse CA3 circuit in vivo

    Dubanet, O., Da Silva, A. F. G., Frick, A., Hirase, Hajime, Beyeler, A. & Leinekugel, X., 2021, In: Cell Reports. 36, 2, 19 p., 109381.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The glymphatic system and Amyotrophic lateral sclerosis

    Eisen, A., Nedergaard, Maiken, Gray, E. & Kiernan, M. C., 2024, In: Progress in Neurobiology. 234, 10 p., 102571.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    RIF1 and KAP1 differentially regulate the choice of inactive versus active X chromosomes

    Enervald, E., Powell, L. M., Boteva, L., Foti, R., Blanes Ruiz, N., Kibar, G., Piszczek, A., Cavaleri, F., Vingron, M., Cerase, A. & Buonomo, S. B. C., 2021, In: EMBO Journal. 40, 22, 16 p., e105862 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Determination of intracellular chloride concentration in glial cell types using fluorescence lifetime imaging microscopy (FLIM)

    Engels, M., Untiet, Verena, Gensch, T., Kovermann, P. & Fahlke, C., 2019. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  21. Published

    Reactive astrocyte nomenclature, definitions, and future directions

    Escartin, C., Galea, E., Lakatos, A., O'Callaghan, J. P., Petzold, G. C., Serrano-Pozo, A., Steinhauser, C., Volterra, A., Carmignoto, G., Agarwal, A., Allen, N. J., Araque, A., Barbeito, L., Barzilai, A., Bergles, D. E., Bonvento, G., Butt, A. M., Chen, W-T., Cohen-Salmon, M., Cunningham, C. & 61 others, Deneen, B., De Strooper, B., Diaz-Castro, B., Farina, C., Freeman, M., Gallo, V., Goldman, J. E., Goldman, Steven Alan, Gotz, M., Gutierrez, A., Haydon, P. G., Heiland, D. H., Hol, E. M., Holt, M. G., Iino, M., Kastanenka, K. V., Kettenmann, H., Khakh, B. S., Koizumi, S., Lee, C. J., Liddelow, S. A., MacVicar, B. A., Magistretti, P., Messing, A., Mishra, A., Molofsky, A. V., Murai, K. K., Norris, C. M., Okada, S., Oliet, S. H. R., Oliveira, J. F., Panatier, A., Parpura, V., Pekna, M., Pekny, M., Pellerin, L., Perea, G., Perez-Nievas, B. G., Pfrieger, F. W., Poskanzer, K. E., Quintana, F. J., Ransohoff, R. M., Riquelme-Perez, M., Robel, S., Rose, C. R., Rothstein, J. D., Rouach, N., Rowitch, D. H., Semyanov, A., Sirko, S., Sontheimer, H., Swanson, R. A., Vitorica, J., Wanner, I., Wood, L. B., Wu, J., Zheng, B., Zimmer, E. R., Zorec, R., Sofroniew, M. V. & Verkhratsky, A., 2021, In: Nature Neuroscience. 24, p. 312–325 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Protocol to study molecule exchange between venous blood and CSF in live mice using transcranial bioluminescence imaging

    Esmail, Tina, Nedergaard, Maiken & Beinlich, Felix Ralf Michael, 2023, In: STAR Protocols. 4, 4, 18 p., 102652.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Grid-climbing Behaviour as a Pain Measure for Cancer-induced Bone Pain and Neuropathic Pain

    Falk, S., Gallego-Pedersen, S. & Petersen, Nicolas Caesar, Jul 2017, In: In Vivo. 31, 4, p. 619-623

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs

    Feng, L., Chao, J., Tian, E., Li, L., Ye, P., Zhang, M., Chen, X., Cui, Q., Sun, G., Zhou, T., Felix, G., Qin, Y., Li, W., Meza, E. D., Klein, J., Ghoda, L., Hu, W., Luo, Y., Dang, W., Hsu, D. & 4 others, Gold, J., Goldman, Steven Alan, Matalon, R. & Shi, Y., 2020, In: Advanced Science. 7, 23, 19 p., 2002155.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A functional observational battery for evaluation of neurological outcomes in a rat model of acute bacterial meningitis

    Fisher, J., Pavan, C., Ohlmeier, L. S., Nilson, B., Lundgaard, I., Linder, A. & Bentzer, P., 2020, In: Intensive Care Medicine Experimental. 8, 1, 17 p., 40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    CHARACTERIZATION OF A RAT MODEL OF ACUTE BACTERIAL MENINGITIS

    Fisher, J., Pavan, C., Linder, A. & Bentzer, P., 2019, In: Shock. 51, Supplement 1 6S, p. 82 1 p., P89.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  27. Published

    Stem cell therapy. Use of differentiated pluripotent stem cells as replacement therapy for treating disease

    Fox, I. J., Daley, G. Q., Goldman, Steven Alan, Huard, J., Kamp, T. J. & Trucco, M., 22 Aug 2014, In: Science (New York, N.Y.). 345, 6199, p. 1-12 12 p., 1247391.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Glia Disease and Repair-Remyelination

    Franklin, R. J. M. & Goldman, Steven Alan, Jul 2015, In: Cold Spring Harbor perspectives in biology. 7, 7, p. 1-28 28 p., a020594.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Remyelination in the Central Nervous System

    Franklin, R. J. M., Bodini, B. & Goldman, Steven Alan, 2024, In: Cold Spring Harbor perspectives in biology. 16, 3, 39 p., a041371.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Feasibility of IVIM parameters from diffusion-weighted imaging at 11.7T MRI for detecting ischemic changes in common carotid artery occlusion rats

    Fujiwara, S., Mori, Yuki, de la Mora, D. M., Akamatsu, Y., Yoshida, K., Shibata, Y., Masuda, T., Ogasawara, K. & Yoshioka, Y., 2020, In: Scientific Reports. 10, 1, 10 p., 8404.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Depth-targeted intracortical microstroke by two-photon photothrombosis in rodent brain

    Fukuda, M., Matsumura, T., Suda, T. & Hirase, Hajime, 2022, In: Neurophotonics. 9, 2, 9 p., 021910.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Perivascular pumping of cerebrospinal fluid in the brain with a valve mechanism

    Gan, Y., Holstein-Rønsbo, Stephanie, Nedergaard, Maiken, Boster, K. A. S., Thomas, J. H. & Kelley, D. H., 2023, In: Journal of the Royal Society, Interface. 20, 206, 17 p., 20230288.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Physiology of Microglia

    Garaschuk, O. & Verkhratsky, A., 2019, Microglia: Methods and Protocols. Garaschuk, O. & Verkhratsky, A. (eds.). Humana Press, p. 27-40 14 p. (Methods in Molecular Biology, Vol. 2034).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  34. Published

    Microglia: The Neural Cells of Nonneural Origin

    Garaschuk, O. & Verkhratsky, A., 2019, Microglia: Methods and Protocols. Garaschuk, O. & Verkhratsky, A. (eds.). Humana Press, p. 3-11 9 p. (Methods in Molecular Biology, Vol. 2034).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  35. Published

    Arterial responses to infusion of glucagon-like peptide-1 in humans: A randomized trial study

    Ghanizada, Hashmat, Christensen, R. H., Al-Karagholi, M. A. M., Elbahi, F. A., Coskun, H. & dlt446, dlt446, 2022, In: Peptides. 150, 8 p., 170736.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    A molecular interactome of the glioblastoma perivascular niche reveals integrin binding sialoprotein as a mediator of tumor cell migration

    Ghochani, Y., Muthukrishnan, S. D., Sohrabi, A., Kawaguchi, R., Condro, M. C., Bastola, S., Gao, F., Qin, Y., Mottahedeh, J., Iruela-Arispe, M. L., Rao, N., Laks, D. R., Liau, L. M., Mathern, G. W., Goldman, Steven Alan, Carmichael, S. T., Nakano, I., Coppola, G., Seidlits, S. K. & Kornblum, H. I., 2022, In: Cell Reports. 41, 3, 25 p., 111511.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Protocol for optical clearing and imaging of fluorescently labeled ex vivo rat brain slices

    Giacomoni, J., Habekost, Mette, Cepeda-Prado, E., Mattsson, B., Ottosson, D. R., Parmar, M. & Kajtez, Janko, 2023, In: STAR Protocols. 4, 1, 18 p., 102041.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Biological sex does not predict glymphatic influx in healthy young, middle aged or old mice

    Giannetto, M., Xia, M., Stæger, Frederik Filip Vinggaard, Metcalfe, T., Vinitsky, H. S., Dang, J. A. M. L., L R Xavier, Anna , Kress, B. T., Nedergaard, Maiken & Hablitz, L. M., 2020, In: Scientific Reports. 10, 1, 8 p., 16073.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Glymphatic fluid transport is suppressed by the aquaporin-4 inhibitor AER-271

    Giannetto, M. J., Gomolka, Ryszard Stefan, Gahn-Martinez, D., Newbold, E. J., Bork, Peter Aleksander Rousing, Chang, E., Gresser, M., Thompson, T., Mori, Yuki & Nedergaard, Maiken, 2024, In: Glia. 72, 5, p. 982-998 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The Glymphatic System and Pain

    Goldman, N., Hablitz, L. M., Mori, Yuki & Nedergaard, Maiken, 2020, In: Medical Acupuncture. 32, 6, p. 373-376 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Progenitor cell-based treatment of glial disease

    Goldman, Steven Alan, 2017, Functional Neural Transplantation IV. Cambridge, MA, United States, Vol. 231. p. 165-189 25 p. (Progress in Brain Research, Vol. 231).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  42. Published

    Transplanted neural progenitors bridge gaps to benefit cord-injured monkeys

    Goldman, Steven Alan, 2018, In: Nature Medicine. 24, 4, p. 388-390 3 p.

    Research output: Contribution to journalJournal articleCommunication

  43. Published

    The role of glial pathology in Huntington's disease

    Goldman, Steven Alan, 2024, Huntington's Disease: Pathogenic Mechanisms and Implications for Therapeutics. Elsevier, p. 337-351 15 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  44. Published

    Glial evolution as a determinant of human behavior and its disorders

    Goldman, Steven Alan, 2020, In: Annals of the New York Academy of Sciences. 1471, 1, p. 72-85 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    Stem and Progenitor Cell-Based Therapy of the Central Nervous System: Hopes, Hype, and Wishful Thinking

    Goldman, Steven Alan, 4 Feb 2016, In: Cell Stem Cell. 18, 2, p. 174-188 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Patience pays in spinal repair

    Goldman, Steven Alan, 2017, In: Journal of Clinical Investigation. 127, 9, p. 3284-3286 3 p.

    Research output: Contribution to journalReviewResearchpeer-review

  47. Published

    How to make an oligodendrocyte

    Goldman, Steven Alan & Kuypers, N. J., 1 Dec 2015, In: Development. 142, 23, p. 3983-3995 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Glial progenitor cell-based repair of the dysmyelinated brain: Progression to the clinic

    Goldman, Steven Alan, Mariani, J. N. & Madsen, P. M., 2021, In: Seminars in Cell and Developmental Biology. 116, p. 62-70 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    Modeling cognition and disease using human glial chimeric mice

    Goldman, Steven Alan, Nedergaard, Maiken & Windrem, M. S., Aug 2015, In: Glia. 63, 8, p. 1483-1493 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation

    Gomolka, Ryszard Stefan, Hablitz, L. M., Mestre, H., Giannetto, M., Du, Ting, Hauglund, Natalie Linea, Xie, L., Peng, W., Martinez, P. M., Nedergaard, Maiken & Mori, Yuki, 2023, In: eLife. 12, 36 p., e82232.

    Research output: Contribution to journalJournal articleResearchpeer-review