- Published
CSF space volumetry using 3D-CISS in Aqp4-deficient mice – quantitative analysis and technical advances
Gomolka, Ryszard Stefan, Nedergaard, Maiken & Mori, Yuki, 2021, Book of Abstracts ESMRMB 2021 Online 38th Annual Scientific Meeting 7-9 October 2021. Springer, Vol. 34. p. S95-6 2 p. (Magnetic Resonance Materials in Physics, Biology, and Medicine; No. 34).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Ultrastructure of precapillary sphincters and the neurovascular unit
Grubb, Søren, 2023, In: Vascular Biology. 5, 1, 15 p., e230011.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular Control of Brain Capillary Blood Flow: In Vivo Imaging Veritas
Grutzendler, J. & Nedergaard, Maiken, 2019, In: Trends in Neurosciences. 42, 8, p. 528-536 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Anoxia increases potassium conductance in hippocampal nerve cells
HANSEN, A. J., Hounsgaard, Jørn Dybkjær & Jahnsen, Henrik, Jul 1982, In: Acta Physiologica Scandinavica. 115, 3, p. 301-310 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia
Hablitz, L. M., Vinitsky, H. S., Sun, Q., Stæger, Frederik Filip Vinggaard, Sigurdsson, B., Mortensen, K. N., Lilius, T. O. & Nedergaard, Maiken, 2019, In: Science Advances. 5, 2, 9 p., eaav5447.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glymphatic system: A novel component of fundamental neurobiology
Hablitz, L. M. & Nedergaard, Maiken, 2021, In: Journal of Neuroscience. 41, 37, p. 7698-7711 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Circadian control of brain glymphatic and lymphatic fluid flow
Hablitz, L. M., Plá, V., Giannetto, M., Vinitsky, H. S., Stæger, Frederik Filip Vinggaard, Metcalfe, T., Nguyen, R., Benrais, A. & Nedergaard, Maiken, 2020, In: Nature Communications. 11, 1, 4411.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The endothelial border to health: Mechanistic evidence of the hyperglycemic culprit of inflammatory disease acceleration
Hansen, N. W., Hansen, A. J. & Sams, A., Mar 2017, In: IUBMB Life. 69, 3, p. 148-161 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Meningeal Lymphangiogenesis and Enhanced Glymphatic Activity in Mice with Chronically Implanted EEG Electrodes
Hauglund, Natalie Linea, Kusk, P., Kornum, Birgitte Rahbek & Nedergaard, Maiken, 2020, In: Journal of Neuroscience. 40, 11, p. 2371-2380 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cleaning the sleeping brain – the potential restorative function of the glymphatic system
Hauglund, Natalie Linea, Pavan, C. & Nedergaard, Maiken, 1 Jun 2020, In: Current Opinion in Physiology. 15, 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of sleep deprivation and NREM sleep stage on physiological brain pulsations
Helakari, H., Järvelä, M., Väyrynen, T., Tuunanen, J., Piispala, J., Kallio, M., Ebrahimi, S. M., Poltojainen, V., Kananen, J., Elabasy, A., Huotari, N., Raitamaa, L., Tuovinen, T., Korhonen, V., Nedergaard, Maiken & Kiviniemi, V., 2023, In: Frontiers in Neuroscience. 17, 17 p., 1275184.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human NREM Sleep Promotes Brain-Wide Vasomotor and Respiratory Pulsations
Helakari, H., Korhonen, V., Holst, S. C., Piispala, J., Kallio, M., Väyrynen, T., Huotari, N., Raitamaa, L., Tuunanen, J., Kananen, J., Järvelä, M., Tuovinen, T., Raatikainen, V., Borchardt, V., Kinnunen, H., Nedergaard, Maiken & Kiviniemi, V., 2022, In: Journal of Neuroscience. 42, 12, p. 2503-2515 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biophysical Modeling of Dopaminergic Denervation Landscapes in the Striatum Reveals New Therapeutic Strategy
Heltberg, Mathias Spliid, Awada, H. N., Lucchetti, Alessandra, Jensen, Mogens Høgh, Dreyer, J. K. & Rasmussen, R. N., 2022, In: eNeuro. 9, 2, 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brain lipidomics and neurodevelopmental outcomes in intrauterine growth restricted piglets fed dairy or vegetable fat diets
Henriksen, Nicole Lind, Asmussen, K. S., Pan, X., Jiang, Pingping, Mori, Yuki, Christiansen, Line Iadsatian, Sprenger, R. R., Ejsing, C. S., Pankratova, Stanislava & Thymann, Thomas, 2022, In: Scientific Reports. 12, 1, 3303.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycogen distribution in mouse hippocampus
Hirase, Hajime, Akther, S., Wang, X. & Oe, Y., 2019, In: Journal of Neuroscience Research. 97, 8, p. 923-932 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Locomotion Induces Fundamentally Different Patterns of Ca2+Signaling in Astrocytes and Neurons
Hirase, Hajime & Nedergaard, Maiken, 2023, In: Function. 4, 4, 2 p., zqad028.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Glia in Health and Disease
Ho, M. S., Verkhratsky, A., Duan, S. & Parpura, V., 2019, In: Frontiers in Molecular Neuroscience. 12, 3 p., 63.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Glymphatic influx and clearance are accelerated by neurovascular coupling: [Inkl. Correction]
Holstein-Rønsbo, Stephanie, Gan, Y., Giannetto, M. J., Rasmussen, Martin Kaag, Sigurdsson, B., Beinlich, Felix Ralf Michael, Rose, Laura, Untiet, Verena, Hablitz, L. M., Kelley, D. H. & Nedergaard, Maiken, 2023, In: Nature Neuroscience. 26, p. 1042–1053Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The continued need for animals to advance brain research
Homberg, J. R., Adan, R. A. H., Alenina, N., Asiminas, A., Bader, M., Beckers, T., Begg, D. P., Blokland, A., Burger, M. E., van Dijk, G., Eisel, U. L. M., Elgersma, Y., Englitz, B., Fernandez-Ruiz, A., Fitzsimons, C. P., van Dam, A-M., Gass, P., Grandjean, J., Havekes, R., Henckens, M. J. A. G. & 54 others, , 2021, In: Neuron. 109, 15, p. 2374-2379 6 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Air pollution, glymphatic impairment, and Alzheimer's disease
Hussain, R., Graham, U., Elder, A. & Nedergaard, Maiken, 2023, In: Trends in Neurosciences. 46, 11, p. 901-911 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
AMELIORATION OF GLYMPHATIC PATHWAY IS CRITICAL FOR LONG TERM RECOVERY FROM TRAUMATIC BRAIN INJURY
Hussain, R., Wang, W., Cheetham-West, A. O., Sun, Q. & Nedergaard, Maiken, 2018, p. A204. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
EARLY ADDRESS OF POST-TRAUMATIC GLYMPHATIC INSUFFICIENCY REDUCES NEURONAL/GLIAL CELL DEATH AND TISSUE DAMAGES
Hussain, R., Wang, W. & Nedergaard, Maiken, 2019, In: Journal of Neurotrauma. 36, 13, p. A-101 1 p., B04-05.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Managing noradrenaline after traumatic brain injury
Hussain, R. & Nedergaard, Maiken, 2024, In: Clinical and Translational Medicine. 14, 1, 3 p., e1562.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Potentiating glymphatic drainage minimizes post-traumatic cerebral oedema
Hussain, R., Tithof, J., Wang, W., Cheetham-West, A., Song, W., Peng, W., Sigurdsson, B., Kim, D., Sun, Q., Peng, S., Pla Requena, Virginia Teresa, Kelley, D. H., Hirase, Hajime, Castorena-Gonzalez, J. A., Weikop, Pia, Goldman, Steven Alan, Davis, M. J. & Nedergaard, Maiken, 2023, In: Nature. 623, p. 992–1000 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts
Hyun, I., Clayton, E. W., Cong, Y., Fujita, M., Goldman, Steven Alan, Hill, L. R., Monserrat, N., Nakauchi, H., Pedersen, R. A., Rooke, H. M., Takahashi, J. & Knoblich, J. A., 2021, In: Stem Cell Reports. 16, 6, p. 1409-1415 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Implications of the discovery of brain lymphatic pathways
Iliff, J. J., Goldman, Steven Alan & Nedergaard, Maiken, 2015, In: Lancet Neurology. 14, 10, p. 977-979 3 p.Research output: Contribution to journal › Journal article › Communication
- Published
Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement
Iwai, Y., Ozawa, K., Yahagi, K., Mishima, Tsuneko, Akther, S., Vo, C. T., Lee, Ashley Bomin, Tanaka, M., Itohara, S. & Hirase, Hajime, 2021, In: Frontiers in Neural Circuits. 15, 16 p., 658343.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Astrocytes in chronic pain and itch
Ji, R., Donnelly, C. R. & Nedergaard, Maiken, 2019, In: Nature Reviews Neuroscience. 20, 11, p. 667-685Research output: Contribution to journal › Review › Research › peer-review
- Published
Impairment of the glymphatic system after diabetes
Jiang, Q., Zhang, L., Ding, G., Davoodi-Bojd, E., Li, Q., Li, L., Sadry, N., Nedergaard, Maiken, Chopp, M. & Zhang, Z., 1 Apr 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 4, p. 1326-1337 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An fMRI-compatible system for targeted electrical stimulation
Jørgensen, Louise Møller, Baandrup, A. O., Mandeville, J., Glud, A. N., Sørensen, J. C. H., Weikop, Pia, Jespersen, B., Hansen, Adam Espe, Thomsen, C. & Knudsen, Gitte Moos, 2022, In: Journal of Neuroscience Methods. 378, 109659.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased interictal synchronicity of respiratory related brain pulsations in epilepsy
Kananen, J., Järvelä, M., Korhonen, V., Tuovinen, T., Huotari, N., Raitamaa, L., Helakari, H., Väyrynen, T., Raatikainen, V., Nedergaard, Maiken, Ansakorpi, H., Jacobs, J., LeVan, P. & Kiviniemi, V., 2022, In: Journal of Cerebral Blood Flow and Metabolism. 42, 10, p. 1840-1853 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered physiological brain variation in drug-resistant epilepsy
Kananen, J., Tuovinen, T., Ansakorpi, H., Rytky, S., Helakari, H., Huotari, N., Raitamaa, L., Raatikainen, V., Rasila, A., Borchardt, V., Korhonen, V., LeVan, P., Nedergaard, Maiken & Kiviniemi, V., 2018, In: Brain and Behavior. 8, 9, p. 1-17 17 p., e01090.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Respiratory-related brain pulsations are increased in epilepsy-a two-centre functional MRI study
Kananen, J., Helakari, H., Korhonen, V., Huotari, N., Jarvela, M., Raitamaa, L., Raatikainen, V., Rajna, Z., Tuovinen, T., Nedergaard, Maiken, Jacobs, J., LeVan, P., Ansakorpi, H. & Kiviniemi, V., 2020, In: Brain Communications. 2, 2, 14 p., 076.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets
Karimy, J. K., Reeves, B. C., Damisah, E., Duy, P. Q., Antwi, P., David, W., Wang, K., Schiff, S. J., Limbrick, D. D. ,. J., Alper, S. L., Warf, B. C., Nedergaard, Maiken, Simard, J. M. & Kahle, K. T., 2020, In: Nature Reviews Neurology. 16, p. 285–296 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
An immortalized human adipose-derived stem cell line with highly enhanced chondrogenic properties
Katz, D. B., Huynh, N. P. T., Savadipour, A., Palte, I. & Guilak, F., 2020, In: Biochemical and Biophysical Research Communications. 530, 1, p. 252-258 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Astrocytic contributions to Huntington's disease pathophysiology
Khakh, B. S. & Goldman, Steven Alan, 2023, In: Annals of the New York Academy of Sciences. 1522, 1, p. 42-59 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Unravelling and Exploiting Astrocyte Dysfunction in Huntington's Disease
Khakh, B. S., Beaumont, V., Cachope, R., Munoz-Sanjuan, I., Goldman, Steven Alan & Grantyn, R., Jul 2017, In: Trends in Neurosciences. 40, 7, p. 422-437 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Repeated low doses of psilocybin increase resilience to stress, lower compulsive actions, and strengthen cortical connections to the paraventricular thalamic nucleus in rats
Kiilerich, K. F., Lorenz, J., Scharff, M. B., Speth, N., Brandt, T. G., Czurylo, J., Xiong, M., Jessen, N. S., Casado-Sainz, A., Shalgunov, Vladimir, Kjærby, Celia, Satała, G., Bojarski, A. J., Jensen, Anders A., Herth, Matthias Manfred, Cumming, P., Overgaard, A. & Palner, M., 2023, In: Molecular Psychiatry. 28, 9, p. 3829-3841Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Donor cell memory confers a metastable state of directly converted cells
Kim, K. P., Li, C., Bunina, D., Jeong, H. W., Ghelman, J., Yoon, J., Shin, B., Park, H., Han, D. W., Zaugg, J. B., Kim, J., Kuhlmann, T., Adams, R. H., Noh, K. M., Goldman, Steven Alan & Schöler, H. R., 2021, In: Cell Stem Cell. 28, 7, p. 1291-1306.e10 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does Global Astrocytic Calcium Signaling Participate in Awake Brain State Transitions and Neuronal Circuit Function?
Kjærby, Celia, Rasmussen, R., Andersen, Mie & Nedergaard, Maiken, Jun 2017, In: Neurochemical Research. 42, 6, p. 1810-1822 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine
Kjærby, Celia, Andersen, Mie, Hauglund, Natalie Linea, Untiet, Verena, Dall, C., Sigurdsson, B., Ding, F., Feng, J., Li, Y., Weikop, Pia, Hirase, Hajime & Nedergaard, Maiken, 2022, In: Nature Neuroscience. 25, p. 1059–1070 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired GABAergic Inhibition in the Prefrontal Cortex of Early Postnatal Phencyclidine (PCP)-Treated Rats
Kjærby, Celia, Broberg, B. V., Kristiansen, Uffe & Dalby, N. O., 2014, In: Cerebral Cortex. 24, 9, p. 2522-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamic fluctuations of the locus coeruleus-norepinephrine system underlie sleep state transitions
Kjærby, Celia, Andersen, Mie, Hauglund, Natalie Linea, Ding, F., Wang, W., Xu, Q., Deng, S., Kang, N., Peng, S., Sun, Q., Dall, C., Jørgensen, P. K., Feng, J., Li, Y., Weikop, Pia, Hirase, Hajime & Nedergaard, Maiken, 2 Sep 2020, 1 p.Research output: Other contribution › Research
- Published
Reply to: 'Do all norepinephrine surges disrupt sleep?'
Kjærby, Celia, Andersen, Mie, Hauglund, Natalie Linea, Untiet, Verena, Dall, C., Ding, F., Hirase, Hajime & Nedergaard, Maiken, 2023, In: Nature Neuroscience. 26, 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Introducing the special issue on “Proteins and Circuits in Memory”
Kjærgaard, M., Petersen, Nicolas Caesar, Sørensen, Jakob Balslev & Takeuchi, T., 2021, In: European Journal of Neuroscience. 54, 8, p. 6691-6695 5 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Human glial chimeric mice reveal astrocytic dependence of JC virus infection
Kondo, Y., Windrem, M. S., Zou, L., Chandler-Militello, D., Schanz, S. J., Auvergne, R. M., Betstadt, S. J., Harrington, A. R., Johnson, M., Kazarov, A., Gorelik, L. & Goldman, Steven Alan, 1 Dec 2014, In: The Journal of Clinical Investigation. 124, 12, p. 5323-36 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brain Morphometry and Longitudinal Relaxation Time of Spontaneously Hypertensive Rats (SHRs) in Early and Intermediate Stages of Hypertension Investigated by 3D VFA-SPGR MRI
Koundal, S., Liu, X., Sanggaard, S., Mortensen, K., Wardlaw, J., Nedergaard, Maiken, Benveniste, H. & Lee, H., 2019, In: Neuroscience. 404, p. 14-26Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased activity of glial glutamate transporter-associated anion channels results in episodic ataxia 6
Kovermann, P., Untiet, Verena, Kolobkova, Y. & Fahlke, C., 2019, In: Glia. 67, S1, p. E216 1 p., T05-034A.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
EARLY INTRODUCTION TO HIGH-INTENSITY INTERVAL TRAINING IN STROKE ASSOCIATES WITH SUSTAINED VIGOROUS-INTENSITY ACTIVITY AT LONG-TERM FOLLOW-UP - RESULTS FROM THE HITPALS STUDY
Krawcyk, R. S., Vinther, A., Petersen, Nicolas Caesar, Faber, Jens, Iversen, Helle Klingenberg, Christensen, T., Lambertsen, K., Klausen, T., Rostrup, E. & Kruuse, Christina Rostrup, 2020, In: International Journal of Stroke. 15, Supplement 1, p. 132 00477 / #2449.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Effect of Home-Based High-Intensity Interval Training in Patients With Lacunar Stroke: A Randomized Controlled Trial
Krawcyk, R. S., Vinther, A., Petersen, Nicolas Caesar, Faber, Jens, Iversen, Helle Klingenberg, Christensen, T., Lambertsen, K. L., Rehman, S., Klausen, T. W., Rostrup, E. & Kruuse, Christina Rostrup, 2019, In: Frontiers in Neurology. 10, 15 p., 664.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Home-based aerobic exercise in patients with lacunar stroke: Design of the HITPALS randomized controlled trial
Krawcyk, R. S., Vinther, A., Petersen, Nicolas Caesar, Faber, Jens, Hansen, R. H., Rostrup, E. & Kruuse, Christina Rostrup, 2019, In: Contemporary Clinical Trials Communications. 14, 9 p., 100332.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Self-Reported Physical Activity and Cardiovascular Disease Risk Factors in Patients with Lacunar Stroke
Krawcyk, R. S., Vinther, A., Petersen, Nicolas Caesar, Faber, Jens, Rehman, S., Iversen, Helle Klingenberg, Christensen, T. & Kruuse, Christina Rostrup, 2019, In: Journal of Stroke & Cerebrovascular Diseases. 28, 8, p. 2168-2176 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perivascular pumping in the mouse brain: Improved boundary conditions reconcile theory, simulation, and experiment
Ladrón-de-Guevara, A., Shang, J. K., Nedergaard, Maiken & Kelley, D. H., 2022, In: Journal of Theoretical Biology. 542, 111103.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contributions of the Na⁺/K⁺-ATPase, NKCC1, and Kir4.1 to hippocampal K⁺ clearance and volume responses
Larsen, B. R., Assentoft, M., Cotrina, M. L., Hua, S. Z., Nedergaard, Maiken, Kaila, K., Voipio, J. & MacAulay, Nanna, Apr 2014, In: Glia. 62, 4, p. 608-22 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NREM sleep upregulates human brain pulsation detected by Ultrafast Magnetic Resonance Encephalography
Larsen, S. M. U., Holst, S. C., Olsen, A. S., Zilstorff, D. B., Pleinert, S., Kiviniemi, V., Jennum, Poul, Nedergaard, Maiken & Knudsen, Gitte Moos, 2021, In: European Neuropsychopharmacology. 53, p. S361-S362 3 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Genetic haplotype of the glymphatic-associated water channel aquaporin 4 modulates slow waves in human non-rapid eye movement sleep
Larsen, S. M. U., Landolt, H. P., Berger, W., Nedergaard, Maiken, Knudsen, Gitte Moos & Holst, S. C., 2019, In: European Neuropsychopharmacology. 29, Supplement 6, p. S563-S564 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Haplotype of the astrocytic water channel AQP4 is associated with slow wave energy regulation in human NREM sleep
Larsen, S. M. U., Landolt, H. P., Berger, W., Nedergaard, Maiken, Knudsen, Gitte Moos & Holst, S. C., May 2020, In: PLOS Biology. 18, 5, 14 p., e3000623.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Astrocyte Specific Remodeling of Plasmalemmal Cholesterol Composition by Ketamine Indicates a New Mechanism of Antidepressant Action
Lasic, E., Lisjak, M., Horvat, A., Bozic, M., Sakanovic, A., Anderluh, G., Verkhratsky, A., Vardjan, N., Jorgacevski, J., Stenovec, M. & Zorec, R., 2019, In: Scientific Reports. 9, 12 p., 10957.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative Gd-DOTA uptake from cerebrospinal fluid into rat brain using 3D VFA-SPGR at 9.4T
Lee, H., Mortensen, K., Sanggaard, S., Koch, P., Brunner, H., Quistorff, B., Nedergaard, Maiken & Benveniste, H., 2018, In: Magnetic Resonance in Medicine. 79, 3, p. 1568-1578 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes
Li, J., Pan, L., Pembroke, W. G., Rexach, J. E., Godoy, M. I., Condro, M. C., Alvarado, A. G., Harteni, M., Chen, Y., Stiles, L., Chen, A. Y., Wanner, I. B., Yang, X., Goldman, Steven Alan, Geschwind, D. H., Kornblum, H. I. & Zhang, Y., 2021, p. E172-E173. 2 p.Research output: Contribution to conference › Poster › Research › peer-review
- Published
Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes
Li, J., Pan, L., Godoy, M., Pembroke, W. G., Rexach, J. E., Condro, M. C., Alvarado, A. G., Harteni, M., Chen, Y., Stiles, L., Chen, A. Y., Wanner, I. B., Yang, X., Goldman, Steven Alan, Geschwind, D. H., Kornblum, H. & Zhang, Y., 2021, In: Nature Communications. 12, 1, 20 p., 3958.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aquaporin 1 and the Na+/K+/2Cl- cotransporter 1 are present in the leptomeningeal vasculature of the adult rodent central nervous system
Li, Q., Aalling, Nadia, Förstera, B., Ertürk, A., Nedergaard, Maiken, Møllgård, Kjeld & L R Xavier, Anna , 2020, In: Fluids and Barriers of the CNS. 17, 15 p., 15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Zika Virus NS4A and NS4B Proteins Deregulate Akt-mTOR Signaling in Human Fetal Neural Stem Cells to Inhibit Neurogenesis and Induce Autophagy
Liang, Q., Luo, Z., Zeng, J., Chen, W., Foo, S., Lee, S., Ge, J., Wang, S., Goldman, Steven Alan, Zlokovic, B. V., Zhao, Z. & Jung, J. U., 3 Nov 2016, In: Cell Stem Cell. 19, 5, p. 663-671 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs
Lilius, T. O., Blomqvist, K., Hauglund, Natalie Linea, Liu, G., Stæger, Frederik Filip Vinggaard, Baerentzen, S., Du, T., Ahlstrom, F., Backman, J. T., Kalso, E. A., Rauhala, P. V. & Nedergaard, Maiken, 2019, In: Journal of Controlled Release. 304, p. 29-38 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glymphatic-assisted perivascular brain delivery of intrathecal small gold nanoparticles
Lilius, T. O., Mortensen, K. N., Deville, C., Lohela, T. J., Stæger, Frederik Filip Vinggaard, Sigurdsson, B., Fiordaliso, E. M., Rosenholm, Marko, Kamphuis, C., Beekman, F. J., Jensen, A. I. & Nedergaard, Maiken, 2023, In: Journal of Controlled Release. 355, p. 135-148 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SPECT/CT imaging reveals CNS-wide modulation of glymphatic cerebrospinal fluid flow by systemic hypertonic saline
Lilius, T. O., Rosenholm, Marko, Klinger, L., Mortensen, K. N., Sigurdsson, B., Mogensen, F. L., Hauglund, Natalie Linea, Nielsen, Malthe Skytte Nordentoft, Rantamaki, T. & Nedergaard, Maiken, 2022, In: iScience. 25, 10, 17 p., 105250.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurements of cerebrospinal fluid production: a review of the limitations and advantages of current methodologies
Liu, G., Ladrón-de-Guevara, A., Izhiman, Y., Nedergaard, Maiken & Du, Ting, 2022, In: Fluids and Barriers of the CNS. 19, 1, 24 p., 101.Research output: Contribution to journal › Review › Research › peer-review
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Direct Measurement of Cerebrospinal Fluid Production in Mice
Liu, G., Mestre, H., Sweeney, A. M., Sun, Q., Weikop, Pia, Du, T. & Nedergaard, Maiken, 2020, In: Cell Reports. 33, 12, 13 p., 108524.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uncovering the anatomical and molecular landscape of the developing entorhinal cortex.
Liu, Y., Bergmann, T. B., Peralvo Vidal, Juan Miguel, Lee, J., Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Gorodkin, Jan, Hyttel, P., Pers, Tune H, witter, M. & Hall, Vanessa Jane, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Development of the entorhinal cortex occurs via parallel lamination during neurogenesis
Liu, Y., Bergmann, T., Mori, Yuki, Peralvo Vidal, Juan Miguel, Pihl, M., Vasistha, Navneet A, Thomsen, Preben Dybdahl, Seemann, Ernst Stefan, Gorodkin, Jan, Hyttel, P., Khodosevich, Konstantin, Witter, M. P. & Hall, Vanessa Jane, 2021, In: Frontiers in Neuroanatomy. 15, 19 p., 663667.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sandwich cortial lamination and single-cell analysis decodes the developing spatial processing system
Liu, Y., Bergmann, T. B., Lee, J., Pfisterer, U. G., Handfield, L-F., Mori, Y., Asenjo Martinez, A., Lisa Vargas, I., Seemann, E. S., Lee, J. T. H., Patikis, N., Peralvo Vidal, J. M., Pihl, M., Kornum, B. R., Thomsen, P. D., Hyttel, P., Witter, M., Khodosevich, K., Gorodkin, J., Hemberg, M. & 2 others, , 2019. 45 p.Research output: Contribution to conference › Paper › Communication
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Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling
Liu, Z., Osipovitch, M., Benraiss, A., Huynh, N. P. T., Foti, R., Bates, J., Chandler-Militello, D., Findling, R. L., Tesar, P. J., Nedergaard, Maiken, Windrem, M. S. & Goldman, Steven Alan, 2019, In: Cell Reports. 27, 13, p. 3832-3843, e1-e6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glymphatic system: implications for drugs for central nervous system diseases
Lohela, T. J., Lilius, T. O. & Nedergaard, Maiken, 2022, In: Nature Reviews Drug Discovery. 21, 10, p. 763-779 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Posthemorrhagic hydrocephalus associates with elevated inflammation and CSF hypersecretion via activation of choroidal transporters
Lolansen, Sara Diana, Rostgaard, Nina, Barbuskaite, Dagne, Capion, T., Olsen, M. H., Norager, N. H., Vilhardt, Frederik, Andreassen, Søren Norge, Toft-Bertelsen, Trine Lisberg, Ye, F., Juhler, Marianne, Keep, R. F. & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 19 p., 62.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pretargeted Imaging beyond the Blood–Brain Barrier: Utopia or Feasible?
Lopes van den Broek, S., Shalgunov, Vladimir, García Vázquez, R., Beschorner, Natalie, Bidesi, N. S. R., Nedergaard, Maiken, Knudsen, Gitte Moos, Sehlin, D., Syvänen, S. & Herth, Matthias Manfred, 2022, In: Pharmaceuticals. 15, 10, 13 p., 1191.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Alzheimer's disease 5xFAD mouse model is best suited to investigate pretargeted imaging approaches beyond the blood-brain barrier
Lopes van den Broek, S. I., Sehlin, D., Andersen, Jens Velde, Aldana, Blanca, Beschorner, Natalie, Nedergaard, Maiken, Knudsen, Gitte Moos, Syvanen, S. & Herth, Matthias Manfred, 2023, In: Frontiers in Nuclear Medicine. 2, 7 p., 1001722.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier
Lou, N., Takano, T., Pei, Y., L R Xavier, Anna , Goldman, Steven Alan & Nedergaard, Maiken, 26 Jan 2016, In: National Academy of Sciences. Proceedings. 113, 4, p. 1074-1079 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Understanding the functions and relationships of the glymphatic system and meningeal lymphatics
Louveau, A., Plog, B. A., Antila, S., Alitalo, K., Nedergaard, Maiken & Kipnis, J., 1 Sep 2017, In: The Journal of Clinical Investigation. 127, 9, p. 3210-3219 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update
Lovell-Badge, R., Anthony, E., Barker, R. A., Bubela, T., Brivanlou, A. H., Carpenter, M., Charo, R. A., Clark, A., Clayton, E., Cong, Y., Daley, G. Q., Fu, J., Fujita, M., Greenfield, A., Goldman, S. A., Hill, L., Hyun, I., Isasi, R., Kahn, J., Kato, K. & 27 others, , 2021, In: Stem Cell Reports. 16, 6, p. 1398-1408 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Glymphatic clearance controls state-dependent changes in brain lactate concentration
Lundgaard, I., Lu, M. L., Yang, E., Peng, W., Mestre, H., Hitomi, E., Deane, R. & Nedergaard, Maiken, Jun 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 6, p. 2112-2124 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct neuronal glucose uptake Heralds activity-dependent increases in cerebral metabolism
Lundgaard, I., Li, B., Xie, L., Kang, H., Sanggaard, S., Haswell, J. D. R., Sun, W., Goldman, S., Blekot, S., Nielsen, Michael Lund, Takano, T., Deane, R. & Nedergaard, Maiken, 2015, In: Nature Communications. 6, 12 p., 6807.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function
Lundgaard, I., Wang, W., Eberhardt, A., Vinitsky, H. S., Reeves, B. C., Peng, S., Lou, N., Hussain, R. & Nedergaard, Maiken, 2018, In: Scientific Reports. 8, 1, 16 p., 2246.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Psilocybin-induced reduction in chronic cluster headache attack frequency correlates with changes in hypothalamic functional connectivity
Madsen, M. K., Petersen, A. S., Stenbæk, Dea Siggaard, Sorensen, I. M., Schionning, H., Fjeld, T., Nykjaer, C., Larsen, S. M. U., Grzywacz, M., Mathiesen, T., Klausen, I., Hansen, O. O., Brendstrup-Brix, K., Linnet, Kristian, Johansen, Sys Stybe, Fisher, P. M., Jensen, Rasmus Herlo Beenfeldt, Knudsen, Gitte Moos & Madsen, M. K., 2022, medRxiv, 17 p.Research output: Working paper › Preprint › Research
- Published
Derivation of telencephalic oligodendrocyte progenitors from human pluripotent stem cells
Major, T., Powers, A. & Tabar, V., Nov 2016, In: Current Protocols in Stem Cell Biology. 39, 1, p. 1H.10.1-1H.10.23 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Glial Chimeric Mice to Define the Role of Glial Pathology in Human Disease
Mariani, J. N., Zou, L. & Goldman, Steven Alan, 2019, Oligodendrocytes. Springer, Vol. 1936. p. 311-331 21 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
TUBE project: Transport-derived ultrafines and the brain effects
Martikainen, M. V., Aakko-Saksa, P., Broek, L. V. D., Cassee, F. R., Carare, R. O., Chew, S., Dinnyes, A., Giugno, R., Kanninen, K. M., Malm, T., Muala, A., Nedergaard, M., Oudin, A., Oyola, P., Pfeiffer, T. V., Rönkkö, T., Saarikoski, S., Sandström, T., Schins, R. P. F., Topinka, J. & 4 others, , 2022, In: International Journal of Environmental Research and Public Health. 19, 1, 14 p., 311.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disruption of Semantic Network in Mild Alzheimer's Disease Revealed by Resting-State fMRI
Mascali, D., DiNuzzo, M., Serra, L., Mangia, S., Maraviglia, B., Bozzali, M. & Giove, F., 2018, In: Neuroscience. 371, p. 38-48 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice
Mathiesen, B. K., Miyakoshi, L. M., Cederroth, C. R., Tserga, E., Versteegh, C., Bork, Peter Aleksander Rousing, Hauglund, Natalie Linea, Gomolka, Ryszard Stefan, Mori, Yuki, Edvall, N. K., Rouse, S., Møllgård, Kjeld, Holt, J. R., Nedergaard, Maiken & Canlon, B., 2023, In: Science Translational Medicine. 15, 702, 13 p., eabq3916.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Brain's Glymphatic System: Current Controversies
Mestre, H., Mori, Yuki & Nedergaard, Maiken, 2020, In: Trends in Neurosciences. 43, 7, p. 458-466 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Cerebrospinal fluid influx drives acute ischemic tissue swelling
Mestre, H., Du, T., Sweeney, A. M., Liu, G., Samson, A. J., Peng, W., Mortensen, K. N., Stæger, F. F., Bork, P. A. R., Bashford, L., Toro, E. R., Tithof, J., Kelley, D. H., Thomas, J. H., Hjorth, P. G., Martens, E. A., Mehta, R. I., Solis, O., Blinder, P., Kleinfeld, D. & 3 others, , 2020, In: Science. 367, 6483, 8 p., eaaw7462.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aquaporin-4-dependent glymphatic solute transport in the rodent brain
Mestre, H., Hablitz, L. M., Xavier, A. L. R., Feng, W., Zou, W., Pu, T., Monai, H., Murlidharan, G., Rivera, R. M. C., Simon, M. J., Pike, M. M., Pla, V., Du, T., Kress, B. T., Wang, X., Plog, B. A., Thrane, A. S., Lundgaard, I., Abe, Y., Yasui, M. & 6 others, , 2018, In: eLife. 7, 31 p., :e40070.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perivascular spaces, glymphatic dysfunction, and small vessel disease
Mestre, H., Kostrikov, S., Mehta, R. I. & Nedergaard, Maiken, 1 Sep 2017, In: Clinical Science. 131, 17, p. 2257-2274 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension
Mestre, H., Tithof, J., Du, T., Song, W., Peng, W., Sweeney, A. M., Olveda, G., Thomas, J. H., Nedergaard, Maiken & Kelley, D. H., 2018, In: Nature Communications. 9, 1, 9 p., 4878.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Periarteriolar spaces modulate cerebrospinal fluid transport into brain and demonstrate altered morphology in aging and Alzheimer’s disease
Mestre, H., Verma, N., Greene, T. D., Lin, L. J. A., Ladron-de-Guevara, A., Sweeney, A. M., Liu, G., Thomas, V. K., Galloway, C. A., de Mesy Bentley, K. L., Nedergaard, Maiken & Mehta, R. I., 2022, In: Nature Communications. 13, 1, 8 p., 3897.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative determination of cellular [Na+] by fluorescence lifetime imaging with CoroNaGreen
Meyer, J., Untiet, Verena, Fahlke, C., Gensch, T. & Rose, C. R., 2019, In: Journal of General Physiology. 151, 11, p. 1319-1331Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Surface periarterial spaces of the mouse brain are open, not porous
Min Rivas, F., Liu, J., Martell, B. C., Du, T., Mestre, H., Nedergaard, Maiken, Tithof, J., Thomas, J. H. & Kelley, D. H., 2020, In: Journal of the Royal Society, Interface. 17, 172, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcranial Direct Current Stimulation (tDCS Induces Adrenergic Receptor-Dependent Microglial Morphological Changes in Mice
Mishima, T., Nagai, T., Yahagi, K., Akther, S., Oe, Y., Monai, H., Kohsaka, S. & Hirase, Hajime, 2019, In: eNeuro. 6, 5, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The state of brain activity modulates cerebrospinal fluid transport
Miyakoshi, L. M., Stæger, Frederik Filip Vinggaard, Li, Q., Pan, C., Xie, L., Kang, H., Pavan, C., Dang, J., Sun, Q., Ertürk, A. & Nedergaard, Maiken, 2023, In: Progress in Neurobiology. 229, 11 p., 102512.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Glymphatic System (En)during Inflammation
Mogensen, F. L., Delle, Christine & Nedergaard, Maiken, 2021, In: International Journal of Molecular Sciences. 22, 14, 20 p., 7491.Research output: Contribution to journal › Review › Research › peer-review
- Published
Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
Mohanty, T., Fisher, J., Bakochi, A., Neumann, A., Cardoso, J. F. P., Karlsson, C. A. Q., Pavan, C., Lundgaard, I., Nilson, B., Reinstrup, P., Bonnevier, J., Cederberg, D., Malmström, J., Bentzer, P. & Linder, A., 2019, In: Nature Communications. 10, 13 p., 1667.Research output: Contribution to journal › Journal article › Research › peer-review
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SPECT imaging of the glymphatic pathway with In-111-labeled ovalbumin in the rat brain
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In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy
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Understanding the functions and relationships of the glymphatic system and meningeal lymphatics
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Remyelination in the Central Nervous System
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Glymphatic fluid transport is suppressed by the aquaporin-4 inhibitor AER-271
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