All journal articles- Maiken Nedergaard, M.D., D.M.Sc. – University of Copenhagen

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All publications for Maiken Nedergaard, M.D., D.M.Sc. and Nedergaard Lab

(Updated Nov 10, 2017)

2017

Wang M, Nedergaard M, Iliff J. (2017) Focal solute trapping and global glymphatic pathway impairment in a murine model of microinfarcts. J Neurosci. 37(11):2870-2877. PMC5354332

Kjaerby C, Rasmussen R, Andersen M, Nedergaard M. (2017) Does Global Astrocytic Calcium Signaling Participate in Awake Brain State Transitions and Neuronal Circuit Function? Neurochem Res 42(6): 1810-1822. PMC5451293

de Leon MJ, Li Y, Okamura N, Tsui WH, Saint Louis LA, Glodzik L, Osorio RS, Fortea J, Butler T, Pirraglia E, Fossati S, Kim HJ, Carare RO, Nedergaard M, Benveniste H, Rusinek H. (2017) CSF clearance in Alzheimer Disease measured with dynamic PET. J Nucl Med. 58(9):1471-1476 PMC5577629

Sun W, Cornwell A, Li J, Peng S, Osorio MJ, Wang S, Benraiss A, Lou N, Goldman SA, Nedergaard M. (2017) SOX9 is an astrocyte-specific nuclear marker in the adult brain outside the neurogenic regions. J Neurosci.37(17): 4493-4507. PMC5413187

Achariyar TM, Li B, Peng W, Verghese PB, Shi Y, McConnell E, Benraiss A, Kasper T, Song W, Takano T, Holtzman DM, Nedergaard M, Deane R. (2017) Erratum to: Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation. Molecular Neurodegen. 12(1):3. PMC5234150

Ratner V, Gao Y, Lee H, Elkin R, Nedergaard M, Benveniste H, Tannenbaum A. (2017) Cerebrospinal and Interstitial Fluid Transport via the Glymphatic Pathway Modeled by Optimal Transport. Neuoimage. (152) 530-537. PMC5490081

Lee H, Mortensen K, Sanggaard S, Koch P, Brunner H, Quistorff B, Nedergaard M, Benveniste H. (2017) Quantitative Gd-DOTA uptake from cerebrospinal fluid into rat brain using 3D VFA-SPGR at 9.4TMagnetic Resonance in Medicine [Epub ahead of print] PMID28627037

Windrem MS, Osipovitch M, Liu Z, Bates J, Chandler-Militello D, Zou L, Munir J, Schanz S, McCoy K, Miller RH, Wang S, Nedergaard M, Findling RL, Tesar PJ, Goldman SA. (2017) Human iPSC glial mouse chimeras reveal glial contributions to schizophrenia. Cell Stem Cell. 21(2):  195-208. PMC5576346

Mestre H, Kostrikov S, Mehta RI, Nedergaard M. (2017) Perivascular spaces, glymphatic dysfunction, and small vessel disease. Clinical Science. 1-18. PMC5567781

Lundgaard I, Lu ML, Yang E, Peng W, Mestre H, Hitomi E, Deane R, Nedergaard M. (2017) Glymphatic clearance controls state-dependent changes in brain lactate concentration. Journal of Cereb Blood Flow Metab 37, 2112-2124. PMC5464705

Jiang Q, Zhang L, Ding G, Davoodi-Bojd E, Li Q, Li L, Sandry N, Nedergaard M, Chopp M, Zhang Z. (2017) Impairment of the glymphatic system after diabetes. Journal of Cereb Blood Flow Metab 37, 1326-1337. PMC5453454

Oberheim Bush NA, Nedergaard M. (2017) Do evolutionary changes in astrocytes contribute to the computational power of the hominid brain? Neurochem Res. [Epub ahead of print] PMID28822066

Louveau H, Plog BA, Antila S, Alitalo K, Nedergaard M, Kipnis J. (2017) Understanding the function of the glymphatic system and meningeal lymphatics. Journal of Clin Invest. 127(9):3210-3219. PMID28862640

Benveniste H, Lee H, Ding F, Sun Q, Al-Bizri E, Makaryus R, Probst S, Nedergaard M, Stein EA, Lu H. (2017) Anesthesia with Dexmedetomidine and Low-dose Isoflurane Increase Solute Transport via the Glymphatic Pathway in Rat Brain When Compared with High-dose Isoflurane. Anesthesiology. [Epub ahead of print] PMID28938276

DiNuzzo M, Nedergaard M. (2017) Brain energetics during the sleep-wake cycle. Current Opinion in Neurobiology. 47: 65-72. PMID29024871

Holstein-Rathlou S, Petersen NC, Nedergaard M. (2017) Voluntary running enhances glymphatic influx in awake behaving, young mice. Neurosci Letters. 662C p. 253-258 [Epub ahead of print] PMID29079431

2016

Bosetti F et al. "Small Blood Vessels: Big Health Problems?": Scientific Recommendations of the National Institutes of Health Workshop. Journal of American Heart Association, 2016 nov 04.

Wang F. et al. "NKCC1 up-regulation contributes to early post-traumatic seizures and increased post-traumatic seizure susceptibility." Brain structure & function. 2016 Sep 1; Epub 2016 Sep 01.

McConnell ED et al. "Cerebral microcirculatory failure after subarachnoid hemorrhage is reversed by hyaluronidase." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Sep; 36(9):1537-52. Epub 2015 Oct 14.

Peng W. et al. "Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease." Neurobiology of disease. 2016 Sep; 93:215-25. Epub 2016 May 24.

Wei HS. et al. "Erythrocytes Are Oxygen-Sensing Regulators of the Cerebral Microcirculation." Neuron. 2016 Aug 17; 91(4):851-62. Epub 2016 Aug 04.

Verkhratsky A, Nedergaard M. "The homeostatic astroglia emerges from evolutionary specialization of neural cells." Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2016 Aug 5; 371(1700)

Lundgaard I. et al. "Glymphatic clearance controls state-dependent changes in brain lactate concentration." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Aug 1; Epub 2016 Aug 01.

Jiang Q. et al. "Impairment of the glymphatic system after diabetes." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Jun 15; Epub 2016 Jun 15.

Benraiss A. et al. "Human glia can both induce and rescue aspects of disease phenotype in Huntington disease." Nature communications. 2016 Jun 7; 7:11758. Epub 2016 Jun 07

Kiviniemi V. et al. "Ultra-fast magnetic resonance encephalography of physiological brain activity - Glymphatic pulsation mechanisms?" Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2016 Jun; 36(6):1033-45. Epub 2015 Dec 21.

Ding F. et al. "Changes in the composition of brain interstitial ions control the sleep-wake cycle." Science. 2016 Apr 29; 352(6285):550-5.

Sreetama SC. et al. "Injured astrocytes are repaired by Synaptotagmin XI-regulated lysosome exocytosis." Cell death and differentiation. 2016 Apr; 23(4):596-607. Epub 2015 Oct 09.

Nedergaard M, Goldman SA. "BRAIN DRAIN." Scientific American. 2016 Mar; 314(3):44-9.

Lou N. et al. "Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier." Proceedings of the National Academy of Sciences of the United States of America. 2016 Jan 26; 113(4):1074-9. Epub 2016 Jan 11.

Staberg M. et al. "Combined EGFR- and notch inhibition display additive inhibitory effect on glioblastoma cell viability and glioblastoma-induced endothelial cell sprouting in vitro." Cancer cell international. 2016 16:34. Epub 2016 Apr 26.

Rasmussen R, Nedergaard M, Petersen NC. "Sulforhodamine 101, a widely used astrocyte marker, can induce cortical seizure-like activity at concentrations commonly used." Scientific reports. 2016 6:30433. Epub 2016 Jul 26. 

Persson M. et al. Urokinase-Type Plasminogen Activator Receptor as a Potential PET Biomarker in Glioblastoma. Journal of Nuclear Medicine. 57, 272-8.

Xie L. et al. A Novel Model of Transient Occlusion of the Middle Cerebral Artery in Awake Mice. Journal of Nature and Science. 2.

2015

Iliff JJ, Goldman SA, Nedergaard M. "Implications of the discovery of brain lymphatic pathways." The Lancet. Neurology. 2015 Oct; 14(10):977-9.

Benveniste H, Hof PR, Nedergaard M, Bechter K. "Modern cerebrospinal fluid flow research and Heinrich Quincke's seminal 1872 article on the distribution of cinnabar in freely moving animals." The Journal of comparative neurology. 2015 Sep 1; 523(13):2017-8.

Liu X et al. "External Dentin Stimulation Induces ATP Release in Human Teeth." Journal of dental research. 2015 Sep; 94(9):1259-66. Epub 2015 Jun 30.

Makaryus R et al.. "Brain maturation in neonatal rodents is impeded by sevoflurane anesthesia." Anesthesiology. 2015 Sep; 123(3):557-68.

Ribeiro Xavier AL. et al. "A Distinct Population of Microglia Supports Adult Neurogenesis in the Subventricular Zone." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 Aug 26; 35(34):11848-61.

Benveniste H. et al. "Modern cerebrospinal fluid flow research and Heinrich Quincke's seminal 1872 article on the distribution of cinnabar in freely moving animals." The Journal of comparative neurology. 2015 Aug 15; 523(12):1748-55. Epub 2015 May 12.

Lee H. et al. "The Effect of Body Posture on Brain Glymphatic Transport." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 Aug 5; 35(31):11034-44.

Goldman SA, Nedergaard M, Windrem MS. "Modeling cognition and disease using human glial chimeric mice." Glia. 2015 Aug; 63(8):1483-93. Epub 2015 May 24.

Wei HS. et al. "156?Capillary-Level Control of Cerebrovascular Tone." Neurosurgery. 2015 Aug; 62 Suppl 1:216-7.

Snyder HM. et al. "Vascular contributions to cognitive impairment and dementia including Alzheimer's disease." Alzheimer's & dementia : the journal of the Alzheimer's Association. 2015 Jun; 11(6):710-7. Epub 2014 Dec 12.

Thrane AS. et al. "Filtering the muddied waters of brain edema." Trends in neurosciences. 2015 Jun; 38(6):333-5. Epub 2015 May 22.

Plog BA, Nedergaard M. "Why have we not yet developed a simple blood test for TBI?" Expert review of neurotherapeutics. 2015 May; 15(5):465-8. Epub 2015 Mar 30.

Lundgaard I. et al. "Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism." Nature communications. 2015 Apr 23; 6:6807. Epub 2015 Apr 23.

O'Donnell J, Ding F, Nedergaard M. "Distinct functional states of astrocytes during sleep and wakefulness: Is norepinephrine the master regulator?" Current sleep medicine reports. 2015 Mar; 1(1):1-8. Epub 2015 Jan 29.

Ratner V. et al. "Optimal-mass-transfer-based estimation of glymphatic transport in living brain." Proceedings of SPIE--the International Society for Optical Engineering. 2015 Feb 21; 9413Epub 2015 Mar 20.

Verkhratsky A, Nedergaard M, Hertz L. "Why are astrocytes important?" Neurochemical research. 2015 Feb; 40(2):389-401. Epub 2014 Aug 12.

Plog BA. et al. "Biomarkers of traumatic injury are transported from brain to blood via the glymphatic system." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 Jan 14; 35(2):518-26.

Nedergaard MK. et al. "18F-FET microPET and microMRI for anti-VEGF and anti-PlGF response assessment in an orthotopic murine model of human glioblastoma." PloS one. 2015 10(2):e0115315. Epub 2015 Feb 13.

Xavier AL. et al. "Ontogeny of CX3CR1-EGFP expressing cells unveil microglia as an integral component of the postnatal subventricular zone." Frontiers in cellular neuroscience. 2015 9:37. Epub 2015 Feb 17.

Jessen NA. et al. "The Glymphatic System: A Beginner's Guide." Neurochemical research. 2015 40(12):2583-99. Epub 2015 May 07.

Iliff JJ, Goldman, SA, and Nedergaard M. (2015) "Implications of the discovery of brain lymphatic pathways". Lancet Neurology. 14(10):977-9. PMC4655610

Xavier RAL. et al. "A Distinct Population of Microglia Supports Adult Neurogenesis in the Subventricular Zone". Journal of Neuroscience 35(34):11848-61. PMC4549398

Thrane S. et al. Filtering the muddied waters of brain edema.Trends in Neuroscience. 38, 333-5.

2014

Snyder HM, Corriveau RA, Craft S, Faber JE, Greenberg SM, Knopman D, Lamb BT, Montine TJ, Nedergaard M, Schaffer CB, Schneider, JA, Wellington C, Wilcock DM, Zipfel GJ, Zlokovic B, Bain LJ, Bosetti F, Galis ZS, Koroshetz W, Carrillo MC (2014 Dec 12). "Vascular contributions to cognitive impairment and dementia including Alzheimer's disease." Alzheimers Dement. In press.

Haydon PG, Nedergaard M (2014 Dec 11). How Do Astrocytes Participate in Neural Plasticity? Cold Spring Harb Perspect Biol. In press.
Fujita T, Chen MJ, Li B, Smith NA, Peng W, Sun W, Toner MJ, Kress BT, Wang L, Benraiss A, Takano T, Wang S, Nedergaard M (2014 Dec 10). Neuronal Transgene Expression in Dominant-Negative SNARE Mice. J Neurosci. 34, 16594-604
Iliff JJ, Chen MJ, Plog BA, Zeppenfeld DM, Soltero M, Yang L, Singh I, Deane R, Nedergaard M (2014 Dec 03). Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury. J Neurosci. 34, 16180-93.
Kress BT, Iliff JJ, Xia M, Wang M, Wei HS, Zeppenfeld D, Xie L, Kang H, Xu Q, Liew JA, Plog BA, Ding F, Deane R, Nedergaard M (2014 Dec 01). Impairment of paravascular clearance pathways in the aging brain. Ann Neurol. 76, 845-61.
Thrane AS, Rangroo Thrane V, Nedergaard M. "Drowning stars: reassessing the role of astrocytes in brain edema." Trends in neurosciences. 2014 Sep 15; Epub 2014 Sep 15.
Kress BT, Iliff JJ, Xia M, Wang M, Wei H, Zeppenfeld D, Xie L, Kang H, Xu Q, Liew J, Plog BA, Ding F, Deane R, Nedergaard M. "Impairment of paravascular clearance pathways in the aging brain." Annals of neurology. 2014 Sep 10; Epub 2014 Sep 10.
2013
Ji RR, Berta T, Nedergaard M. "Glia and pain: Is chronic pain a gliopathy?" Pain. 154 Suppl 1, S10-28
Langevin H, Fujita T, Bouffard N, Takano T, Koptiuch C, Badger G, Nedergaard M. "Fibroblast cytoskeletal remodeling induced by tissue stretch involves ATP signaling." Journal of cellular physiology. 2013 Sep; 228(9):1922-6.
Langevin HM, Nedergaard M, Howe A. "Cellular control of connective tissue matrix tension." Journal of cellular biochemistry. 2013 Aug; 114(8):1714-9.
Ren Z, Iliff JJ, Yang L, Yang J, Chen X, Chen MJ, Giese RN, Wang B, Shi X, Nedergaard M. "'Hit & Run' model of closed-skull traumatic brain injury (TBI) reveals complex patterns of post-traumatic AQP4 dysregulation." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2013 Jun; 33(6):834-45. Epub 2013 Feb 27.
Goldman N, Chandler-Militello D, Langevin HM, Nedergaard M, Takano T. "Purine receptor mediated actin cytoskeleton remodeling of human fibroblasts."Cell calcium. 2013 Apr; 53(4):297-301. Epub 2013 Feb 22.
Iliff JJ, Lee H, Yu M, Feng T, Logan J, Nedergaard M, Benveniste H. "Brain-wide pathway for waste clearance captured by contrast-enhanced MRI."The Journal of clinical investigation. 2013 Mar 1; 123(3):1299-309. Epub 2013 Feb 22.
Iliff JJ, Nedergaard M. "A link between glial Ca2+ signaling and hypoxia in aging?" Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2013 Feb; 33(2):170. Epub 2012 Dec 05.
Sun W, McConnell E, Pare JF, Xu Q, Chen M, Peng W, Lovatt D, Han X, Smith Y, Nedergaard M. "Glutamate-dependent neuroglial calcium signaling differs between young and adult brain." Science. 2013 Jan 11; 339(6116):197-200.
2012
Thrane AS, Thrane VR, Zeppenfeld D, Lou N, Xu Q, Nagelhus EA, Nedergaard M. "General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex." Proceedings of the National Academy of Sciences of the United States of America. 2012 Nov 13; 109(46):18974-9. Epub 2012 Oct 29.
O'Donnell J, Zeppenfeld D, McConnell E, Pena S, Nedergaard M. "Norepinephrine: a neuromodulator that boosts the function of multiple cell types to optimize CNS performance." Neurochemical research. 2012 Nov; 37(11):2496-512. Epub 2012 Jun 21.
Chen MJ, Kress B, Han X, Moll K, Peng W, Ji RR, Nedergaard M. "Astrocytic CX43 hemichannels and gap junctions play a crucial role in development of chronic neuropathic pain following spinal cord injury." Glia. 2012 Nov; 60(11):1660-70. Epub 2012 Aug 01.
Goldman SA, Nedergaard M, Windrem MS. "Glial progenitor cell-based treatment and modeling of neurological disease." Science. 2012 Oct 26; 338(6106):491-5.
Thrane VR, Thrane AS, Chang J, Alleluia V, Nagelhus EA, Nedergaard M. "Real-time analysis of microglial activation and motility in hepatic and hyperammonemic encephalopathy." Neuroscience. 2012 Sep 18; 220:247-55. Epub 2012 Jun 21.
Iliff JJ, Wang M, Liao Y, Plogg BA, Peng W, Gundersen GA, Benveniste H, Vates GE, Deane R, Goldman SA, Nagelhus EA, Nedergaard M. "A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid ?." Science translational medicine. 2012 Aug 15; 4(147):147ra111.
Nedergaard M, Verkhratsky A. "Artifact versus reality--how astrocytes contribute to synaptic events." Glia. 2012 Jul; 60(7):1013-23. Epub 2012 Jan 06.
Wang F, Xu Q, Wang W, Takano T, Nedergaard M. "Bergmann glia modulate cerebellar Purkinje cell bistability via Ca2+-dependent K+ uptake." Proceedings of the National Academy of Sciences of the United States of America. 2012 May 15; 109(20):7911-6. Epub 2012 Apr 30.
Lovatt D, Xu Q, Liu W, Takano T, Smith NA, Schnermann J, Tieu K, Nedergaard M. "Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity." Proceedings of the National Academy of Sciences of the United States of America. 2012 Apr 17; 109(16):6265-70. Epub 2012 Mar 15.
Messing A, Brenner M, Feany MB, Nedergaard M, Goldman JE. "Alexander disease." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012 Apr 11; 32(15):5017-23.
Wang F, Smith NA, Xu Q, Fujita T, Baba A, Matsuda T, Takano T, Bekar L, Nedergaard M. "Astrocytes modulate neural network activity by Ca²+-dependent uptake of extracellular K+." Science signaling. 2012 Apr 3; 5(218):ra26. Epub 2012 Apr 03.
Nedergaard MK, Hedegaard CJ, Poulsen HS. "Targeting the epidermal growth factor receptor in solid tumor malignancies." BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy. 2012 Apr 1; 26(2):83-99.
Huang C, Han X, Li X, Lam E, Peng W, Lou N, Torres A, Yang M, Garre JM, Tian GF, Bennett MV, Nedergaard M, Takano T. "Critical role of connexin 43 in secondary expansion of traumatic spinal cord injury." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012 Mar 7; 32(10):3333-8.
Torres A, Wang F, Xu Q, Fujita T, Dobrowolski R, Willecke K, Takano T, Nedergaard M. "Extracellular Ca²? acts as a mediator of communication from neurons to glia." Science signaling. 2012 Jan 24; 5(208):ra8. Epub 2012 Jan 24.
Fujita T, Williams EK, Jensen TK, Smith NA, Takano T, Tieu K, Nedergaard M. "Cultured astrocytes do not release adenosine during hypoxic conditions." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2012 Jan; 32(1):e1-7. Epub 2011 Oct 12.
Wang M, Iliff JJ, Liao Y, Chen MJ, Shinseki MS, Venkataraman A, Cheung J, Wang W, Nedergaard M. "Cognitive deficits and delayed neuronal loss in a mouse model of multiple microinfarcts." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012 32(50):17948-60.
Cotrina ML, Nedergaard M. "Brain connexins in demyelinating diseases: therapeutic potential of glial targets." Brain research. 2012 1487:61-8. Epub 2012 Jul 10.
Bennett MV, Garré JM, Orellana JA, Bukauskas FF, Nedergaard M, Sáez JC. "Connexin and pannexin hemichannels in inflammatory responses of glia and neurons." Brain research. 2012 1487:3-15. Epub 2012 Sep 10.
Oberheim NA, Goldman SA, Nedergaard M. "Heterogeneity of astrocytic form and function." Methods in molecular biology. 2012 814:23-45.
Verkhratsky A, Sofroniew MV, Messing A, Delanerolle NC, Rempe D, Rodriguez Arellano JJ, Nedergaard M. "Neurological diseases as primary gliopathies: a reassessment of neurocentrism." ASN neuro. 2012 4(3)Epub 2012 Apr 05.
Bekar LK, Wei HS, Nedergaard M. "The locus coeruleus-norepinephrine network optimizes coupling of cerebral blood volume with oxygen demand." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2012 32(12):2135-45. Epub 2012 Aug 08.
Enger R, Gundersen GA, Haj-Yasein NN, Eilert-Olsen M, Thoren AE, Vindedal GF, Petersen PH, Skare O, Nedergaard M, Ottersen OP, Nagelhus EA. "Molecular scaffolds underpinning macroglial polarization: an analysis of retinal Müller cells and brain astrocytes in mouse." Glia. 2012 60(12):2018-26. Epub 2012 Sep 17.
Takano T, Chen X, Luo F, Fujita T, Ren Z, Goldman N, Zhao Y, Markman JD, Nedergaard M. "Traditional acupuncture triggers a local increase in adenosine in human subjects." The journal of pain : official journal of the American Pain Society. 2012 13(12):1215-23.
Verkhratsky A, Pankratov Y, Lalo U, Nedergaard M. "P2X receptors in neuroglia." Wiley interdisciplinary reviews. Membrane transport and signaling. 2012 1(2)
2011
Christensen DJ, Nedergaard M. "Two-photon in vivo imaging of cells." Pediatric nephrology (Berlin, Germany). 2011 Sep; 26(9):1483-9. Epub 2011 Mar 15.

Thrane AS, Rappold PM, Fujita T, Torres A, Bekar LK, Takano T, Peng W, Wang F, Thrane VR, Enger R, Haj-Yasein NN, Skare O, Holen T, Klungland A, Ottersen OP, Nedergaard M, Nagelhus EA. "Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema." Proceedings of the National Academy of Sciences of the United States of America. 2011 Jan 11; 108(2):846-51. Epub 2010 Dec 27.

Kasischke KA, Lambert EM, Panepento B, Sun A, Gelbard HA, Burgess RW, Foster TH, Nedergaard M. "Two-photon NADH imaging exposes boundaries of oxygen diffusion in cortical vascular supply regions." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2011 Jan; 31(1):68-81. Epub 2010 Sep 22.
2010
Hertz L, Lovatt D, Goldman SA, Nedergaard M. "Adrenoceptors in brain: cellular gene expression and effects on astrocytic metabolism and [Ca(2+)]i." Neurochemistry international. 2010 Nov; 57(4):411-20. Epub 2010 Apr 07.
Rempe DA, Nedergaard M. "Targeting glia for treatment of neurological disease." Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2010 Oct; 7(4):335-7.
Kimelberg HK, Nedergaard M. "Functions of astrocytes and their potential as therapeutic targets." Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2010 Oct; 7(4):338-53.
Kang J, Kang N, Yu Y, Zhang J, Petersen N, Tian GF, Nedergaard M. "Sulforhodamine 101 induces long-term potentiation of intrinsic excitability and synaptic efficacy in hippocampal CA1 pyramidal neurons."Neuroscience. 2010 Sep 15; 169(4):1601-9. Epub 2010 Jun 19.
Vates GE, Takano T, Zlokovic B, Nedergaard M. "Pericyte constriction after stroke: the jury is still out." Nature medicine. 2010 Sep; 16(9):959; author reply 960.
Goldman N, Chen M, Fujita T, Xu Q, Peng W, Liu W, Jensen TK, Pei Y, Wang F, Han X, Chen JF, Schnermann J, Takano T, Bekar L, Tieu K, Nedergaard M. "Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture." Nature neuroscience. 2010 Jul; 13(7):883-8. Epub 2010 May 30.
Zhang S, Li B, Lovatt D, Xu J, Song D, Goldman SA, Nedergaard M, Hertz L, Peng L. "5-HT2B receptors are expressed on astrocytes from brain and in culture and are a chronic target for all five conventional 'serotonin-specific reuptake inhibitors'." Neuron glia biology. 2010 May; 6(2):113-25. Epub 2010 Sep 16.
Nedergaard M, Rodríguez JJ, Verkhratsky A. "Glial calcium and diseases of the nervous system." Cell calcium. 2010 Feb; 47(2):140-9. Epub 2009 Dec 31.
Nedergaard M, Verkhratsky A. "Calcium dyshomeostasis and pathological calcium signalling in neurological diseases." Cell calcium. 2010 Feb; 47(2):101-2. Epub 2010 Jan 15.
2009
Rempe DA, Takano T, Nedergaard M. "TR(I)Pping towards treatment for ischemia." Nature neuroscience. 2009 Oct; 12(10):1215-6.
Peng W, Cotrina ML, Han X, Yu H, Bekar L, Blum L, Takano T, Tian GF, Goldman SA, Nedergaard M. "Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury." Proceedings of the National Academy of Sciences of the United States of America. 2009 Jul 28; 106(30):12489-93. Epub 2009 Jul 27.
Cotrina ML, Nedergaard M. "Physiological and pathological functions of P2X7 receptor in the spinal cord." Purinergic signalling. 2009 Jun; 5(2):223-32. Epub 2009 Feb 11.
Oberheim NA, Takano T, Han X, He W, Lin JH, Wang F, Xu Q, Wyatt JD, Pilcher W, Ojemann JG, Ransom BR, Goldman SA, Nedergaard M. "Uniquely hominid features of adult human astrocytes." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2009 Mar 11; 29(10):3276-87.
Takano T, Oberheim N, Cotrina ML, Nedergaard M. "Astrocytes and ischemic injury." Stroke; a journal of cerebral circulation. 2009 Mar; 40(3 Suppl):S8-12. Epub 2008 Dec 08.
Hedley-Whyte ET, Goldman JE, Nedergaard M, Friedman A, Han X, Schmidt RE, Powers JM. "Hyaline protoplasmic astrocytopathy of neocortex." Journal of neuropathology and experimental neurology. 2009 Feb; 68(2):136-47.
Takano T, Nedergaard M. "Deciphering migraine." The Journal of clinical investigation. 2009 Jan; 119(1):16-9.
Wang X, Takano T, Nedergaard M. "Astrocytic calcium signaling: mechanism and implications for functional brain imaging." Methods in molecular biology. 2009 489:93-109.

2008

Windrem MS, Schanz SJ, Guo M, Tian GF, Washco V, Stanwood N, Rasband M, Roy NS, Nedergaard M, Havton LA, Wang S, Goldman SA. "Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse." Cell stem cell. 2008 Jun 5; 2(6):553-65.

Xu H, Hu F, Sado Y, Ninomiya Y, Borza DB, Ungvari Z, Lagamma EF, Csiszar A, Nedergaard M, Ballabh P. "Maturational changes in laminin, fibronectin, collagen IV, and perlecan in germinal matrix, cortex, and white matter and effect of betamethasone." Journal of neuroscience research. 2008 May 15; 86(7):1482-500.
Kang J, Kang N, Lovatt D, Torres A, Zhao Z, Lin J, Nedergaard M. "Connexin 43 hemichannels are permeable to ATP."The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 Apr 30; 28(18):4702-11.
Oberheim NA, Tian GF, Han X, Peng W, Takano T, Ransom B, Nedergaard M. "Loss of astrocytic domain organization in the epileptic brain." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 Mar 26; 28(13):3264-76.
Lin JH, Lou N, Kang N, Takano T, Hu F, Han X, Xu Q, Lovatt D, Torres A, Willecke K, Yang J, Kang J, Nedergaard M. "A central role of connexin 43 in hypoxic preconditioning." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 Jan 16; 28(3):681-95.
Neuwelt E, Abbott NJ, Abrey L, Banks WA, Blakley B, Davis T, Engelhardt B, Grammas P, Nedergaard M, Nutt J, Pardridge W, Rosenberg GA, Smith Q, Drewes LR. "Strategies to advance translational research into brain barriers." The Lancet. Neurology. 2008 Jan; 7(1):84-96.
Bekar L, Libionka W, Tian GF, Xu Q, Torres A, Wang X, Lovatt D, Williams E, Takano T, Schnermann J, Bakos R, Nedergaard M. "Adenosine is crucial for deep brain stimulation-mediated attenuation of tremor." Nature medicine. 2008 Jan; 14(1):75-80. Epub 2007 Dec 23.
Bekar LK, He W, Nedergaard M. "Locus coeruleus alpha-adrenergic-mediated activation of cortical astrocytes in vivo." Cerebral cortex (New York, N.Y. : 1991). 2008 18(12):2789-95. Epub 2008 Mar 27.
Cotrina ML, Lin JH, Nedergaard M. "Adhesive properties of connexin hemichannels." Glia. 2008 56(16):1791-8.

2007

Lovatt D, Sonnewald U, Waagepetersen HS, Schousboe A, He W, Lin JH, Han X, Takano T, Wang S, Sim FJ, Goldman SA, Nedergaard M. "The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2007 Nov 7; 27(45):12255-66.

Iadecola C, Nedergaard M. "Glial regulation of the cerebral microvasculature." Nature neuroscience. 2007 Nov; 10(11):1369-76.
Braun A, Xu H, Hu F, Kocherlakota P, Siegel D, Chander P, Ungvari Z, Csiszar A, Nedergaard M, Ballabh P. "Paucity of pericytes in germinal matrix vasculature of premature infants." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2007 Oct 31; 27(44):12012-24.
Jaiswal JK, Fix M, Takano T, Nedergaard M, Simon SM. "Resolving vesicle fusion from lysis to monitor calcium-triggered lysosomal exocytosis in astrocytes." Proceedings of the National Academy of Sciences of the United States of America. 2007 Aug 28; 104(35):14151-6. Epub 2007 Aug 21.
Takano T, Tian GF, Peng W, Lou N, Lovatt D, Hansen AJ, Kasischke KA, Nedergaard M. "Cortical spreading depression causes and coincides with tissue hypoxia." Nature neuroscience. 2007 Jun; 10(6):754-62. Epub 2007 Apr 29.
Takano T, Nedergaard M. "DM-nitrophen provides physiologically significant increases of intracellular [Ca2+] in the presence of Mg2+." Cell calcium. 2007 May; 41(5):503-4. Epub 2006 Oct 19.
Ballabh P, Xu H, Hu F, Braun A, Smith K, Rivera A, Lou N, Ungvari Z, Goldman SA, Csiszar A, Nedergaard M. "Angiogenic inhibition reduces germinal matrix hemorrhage." Nature medicine. 2007 Apr; 13(4):477-85. Epub 2007 Apr 01.
Lin JH, Takano T, Arcuino G, Wang X, Hu F, Darzynkiewicz Z, Nunes M, Goldman SA, Nedergaard M. "Purinergic signaling regulates neural progenitor cell expansion and neurogenesis." Developmental biology. 2007 Feb 1; 302(1):356-66. Epub 2006 Sep 16.
Takano T, Han X, Deane R, Zlokovic B, Nedergaard M. "Two-photon imaging of astrocytic Ca2+ signaling and the microvasculature in experimental mice models of Alzheimer's disease." Annals of the New York Academy of Sciences. 2007 Feb; 1097:40-50.
2006
Oberheim NA, Wang X, Goldman S, Nedergaard M. "Astrocytic complexity distinguishes the human brain." Trends in neurosciences. 2006 Oct; 29(10):547-53. Epub 2006 Aug 30.
Tian GF, Takano T, Lin JH, Wang X, Bekar L, Nedergaard M. "Imaging of cortical astrocytes using 2-photon laser scanning microscopy in the intact mouse brain." Advanced drug delivery reviews. 2006 Sep 15; 58(7):773-87. Epub 2006 Aug 04.
Wang X, Lou N, Xu Q, Tian GF, Peng WG, Han X, Kang J, Takano T, Nedergaard M. "Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo." Nature neuroscience. 2006 Jun; 9(6):816-23. Epub 2006 May 14.
Anderson CM, Nedergaard M. "Emerging challenges of assigning P2X7 receptor function and immunoreactivity in neurons." Trends in neurosciences. 2006 May; 29(5):257-62. Epub 2006 Mar 27.
El-Khoury N, Braun A, Hu F, Pandey M, Nedergaard M, Lagamma EF, Ballabh P. "Astrocyte end-feet in germinal matrix, cerebral cortex, and white matter in developing infants." Pediatric research. 2006 May; 59(5):673-9.
Takano T, Tian GF, Peng W, Lou N, Libionka W, Han X, Nedergaard M. "Astrocyte-mediated control of cerebral blood flow."Nature neuroscience. 2006 Feb; 9(2):260-7. Epub 2005 Dec 25.
2005
Takano T, Kang J, Jaiswal JK, Simon SM, Lin JH, Yu Y, Li Y, Yang J, Dienel G, Zielke HR, Nedergaard M. "Receptor-mediated glutamate release from volume sensitive channels in astrocytes." Proceedings of the National Academy of Sciences of the United States of America. 2005 Nov 8; 102(45):16466-71. Epub 2005 Oct 27.
Ballabh P, Hu F, Kumarasiri M, Braun A, Nedergaard M. "Development of tight junction molecules in blood vessels of germinal matrix, cerebral cortex, and white matter." Pediatric research. 2005 Oct; 58(4):791-8.
Tian GF, Azmi H, Takano T, Xu Q, Peng W, Lin J, Oberheim N, Lou N, Wang X, Zielke HR, Kang J, Nedergaard M. "An astrocytic basis of epilepsy." Nature medicine. 2005 Sep; 11(9):973-81. Epub 2005 Aug 14.
Nedergaard M, Dirnagl U. "Role of glial cells in cerebral ischemia." Glia. 2005 Jun; 50(4):281-6.
Xu J, Kang N, Jiang L, Nedergaard M, Kang J. "Activity-dependent long-term potentiation of intrinsic excitability in hippocampal CA1 pyramidal neurons." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2005 Feb 16; 25(7):1750-60.
Kang N, Xu J, Xu Q, Nedergaard M, Kang J. "Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons." Journal of neurophysiology. 2005 94(6):4121-30. Epub 2005 Sep 14.
Singh Roy N, Nakano T, Xuing L, Kang J, Nedergaard M, Goldman SA. "Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells." Experimental neurology. 2005 196(2):224-34. Epub 2005 Sep 29.
2004
Liu QS, Xu Q, Kang J, Nedergaard M. "Astrocyte activation of presynaptic metabotropic glutamate receptors modulates hippocampal inhibitory synaptic transmission." Neuron glia biology. 2004 Nov; 1(4):307-16.
Kang N, Jiang L, He W, Xu J, Nedergaard M, Kang J. "Presynaptic inactivation of action potentials and postsynaptic inhibition of GABAA currents contribute to KA-induced disinhibition in CA1 pyramidal neurons." Journal of neurophysiology. 2004 Aug; 92(2):873-82. Epub 2004 Mar 03.
Wang X, Arcuino G, Takano T, Lin J, Peng WG, Wan P, Li P, Xu Q, Liu QS, Goldman SA, Nedergaard M. "P2X7 receptor inhibition improves recovery after spinal cord injury." Nature medicine. 2004 Aug; 10(8):821-7. Epub 2004 Jul 18.
Ballabh P, Braun A, Nedergaard M. "Anatomic analysis of blood vessels in germinal matrix, cerebral cortex, and white matter in developing infants." Pediatric research. 2004 Jul; 56(1):117-24. Epub 2004 May 05.
Ballabh P, Braun A, Nedergaard M. "The blood-brain barrier: an overview: structure, regulation, and clinical implications." Neurobiology of disease. 2004 Jun; 16(1):1-13.
Liu QS, Xu Q, Arcuino G, Kang J, Nedergaard M. "Astrocyte-mediated activation of neuronal kainate receptors." Proceedings of the National Academy of Sciences of the United States of America. 2004 Mar 2; 101(9):3172-7. Epub 2004 Feb 06.
Roy NS, Nakano T, Keyoung HM, Windrem M, Rashbaum WK, Alonso ML, Kang J, Peng W, Carpenter MK, Lin J, Nedergaard M, Goldman SA. "Telomerase immortalization of neuronally restricted progenitor cells derived from the human fetal spinal cord." Nature biotechnology. 2004 Mar; 22(3):297-305. Epub 2004 Feb 15.
Simard M, Nedergaard M. "The neurobiology of glia in the context of water and ion homeostasis." Neuroscience. 2004 129(4):877-96.
2003
Simard M, Arcuino G, Takano T, Liu QS, Nedergaard M. "Signaling at the gliovascular interface." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2003 Oct 8; 23(27):9254-62.
Ransom B, Behar T, Nedergaard M. "New roles for astrocytes (stars at last)." Trends in neurosciences. 2003 Oct; 26(10):520-2.
Nedergaard M, Ransom B, Goldman SA. "New roles for astrocytes: redefining the functional architecture of the brain." Trends in neurosciences. 2003 Oct; 26(10):523-30.
Anderson CM, Nedergaard M. "Astrocyte-mediated control of cerebral microcirculation." Trends in neurosciences. 2003 Jul; 26(7):340-4; author reply 344-5.
Nunes MC, Roy NS, Keyoung HM, Goodman RR, McKhann G, Jiang L, Kang J, Nedergaard M, Goldman SA. "Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain." Nature medicine. 2003 Apr; 9(4):439-47. Epub 2003 Mar 10.
Lin JH, Yang J, Liu S, Takano T, Wang X, Gao Q, Willecke K, Nedergaard M. "Connexin mediates gap junction-independent resistance to cellular injury." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2003 Jan 15; 23(2):430-41.
2002
Nedergaard M, Takano T, Hansen AJ. "Beyond the role of glutamate as a neurotransmitter." Nature reviews. Neuroscience. 2002 Sep; 3(9):748-55.
Goldman SA, Nedergaard M. "Erythropoietin strikes a new cord." Nature medicine. 2002 Aug; 8(8):785-7.
Arcuino G, Lin JH, Takano T, Liu C, Jiang L, Gao Q, Kang J, Nedergaard M. "Intercellular calcium signaling mediated by point-source burst release of ATP." Proceedings of the National Academy of Sciences of the United States of America. 2002 Jul 23; 99(15):9840-5. Epub 2002 Jul 03.
Lin JH, Takano T, Cotrina ML, Arcuino G, Kang J, Liu S, Gao Q, Jiang L, Li F, Lichtenberg-Frate H, Haubrich S, Willecke K, Goldman SA, Nedergaard M. "Connexin 43 enhances the adhesivity and mediates the invasion of malignant glioma cells." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2002 Jun 1; 22(11):4302-11.
Cotrina ML, Nedergaard M. "Astrocytes in the aging brain." Journal of neuroscience research. 2002 Jan 1; 67(1):1-10.
2001
Takano T, Lin JH, Arcuino G, Gao Q, Yang J, Nedergaard M. "Glutamate release promotes growth of malignant gliomas." Nature medicine. 2001 Sep; 7(9):1010-5.
Cotrina ML, Gao Q, Lin JH, Nedergaard M. "Expression and function of astrocytic gap junctions in aging." Brain research. 2001 May 18; 901(1-2):55-61.
Jiang L, Xu J, Nedergaard M, Kang J. "A kainate receptor increases the efficacy of GABAergic synapses." Neuron. 2001 May; 30(2):503-13.
2000
Zhang W, Couldwell WT, Song H, Takano T, Lin JH, Nedergaard M. "Tamoxifen-induced enhancement of calcium signaling in glioma and MCF-7 breast cancer cells." Cancer research. 2000 Oct 1; 60(19):5395-400.
Cotrina ML, Lin JH, López-García JC, Naus CC, Nedergaard M. "ATP-mediated glia signaling." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2000 Apr 15; 20(8):2835-44.
Martins-Ferreira H, Nedergaard M, Nicholson C. "Perspectives on spreading depression." Brain research. Brain research reviews. 2000 Apr; 32(1):215-34.
Jiang L, Sun S, Nedergaard M, Kang J. "Paired-pulse modulation at individual GABAergic synapses in rat hippocampus." The Journal of physiology. 2000 Mar 1; 523 Pt 2:425-39.
Roy NS, Wang S, Jiang L, Kang J, Benraiss A, Harrison-Restelli C, Fraser RA, Couldwell WT, Kawaguchi A, Okano H, Nedergaard M, Goldman SA. "In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus." Nature medicine. 2000 Mar; 6(3):271-7.
Roy NS, Benraiss A, Wang S, Fraser RA, Goodman R, Couldwell WT, Nedergaard M, Kawaguchi A, Okano H, Goldman SA. "Promoter-targeted selection and isolation of neural progenitor cells from the adult human ventricular zone." Journal of neuroscience research. 2000 Feb 1; 59(3):321-31.
Grafstein B, Liu S, Cotrina ML, Goldman SA, Nedergaard M. "Meningeal cells can communicate with astrocytes by calcium signaling." Annals of neurology. 2000 Jan; 47(1):18-25.
Cotrina, M.; Nedergaard, M. "ATP as a messenger in astrocyte-neuronal communication". The Neuroscientist. 2000; 6(2): 120-126.
1999
Simard M, Couldwell WT, Zhang W, Song H, Liu S, Cotrina ML, Goldman S, Nedergaard M. "Glucocorticoids-potent modulators of astrocytic calcium signaling." Glia. 1999 Oct; 28(1):1-12.
Zhang W, Couldwell WT, Simard MF, Song H, Lin JH, Nedergaard M. "Direct gap junction communication between malignant glioma cells and astrocytes."Cancer research. 1999 Apr 15; 59(8):1994-2003.
Williams S, Leventhal C, Lemmon V, Nedergaard M, Goldman SA. "Estrogen promotes the initial migration and inception of NgCAM-dependent calcium-signaling by new neurons of the adult songbird brain." Molecular and cellular neurosciences. 1999 Jan; 13(1):41-55.
1998
Cotrina ML, Lin JH, Nedergaard M. "Cytoskeletal assembly and ATP release regulate astrocytic calcium signaling." The Journal of neuroscience : the official journal of the Society for Neuroscience. 1998 Nov 1; 18(21):8794-804.
Lin JH, Weigel H, Cotrina ML, Liu S, Bueno E, Hansen AJ, Hansen TW, Goldman S, Nedergaard M. "Gap-junction-mediated propagation and amplification of cell injury." Nature neuroscience. 1998 Oct; 1(6):494-500.
Pincus DW, Keyoung HM, Harrison-Restelli C, Goodman RR, Fraser RA, Edgar M, Sakakibara S, Okano H, Nedergaard M, Goldman SA. "Fibroblast growth factor-2/brain-derived neurotrophic factor-associated maturation of new neurons generated from adult human subependymal cells." Annals of neurology. 1998 May; 43(5):576-85.
Cotrina ML, Kang J, Lin JH, Bueno E, Hansen TW, He L, Liu Y, Nedergaard M. "Astrocytic gap junctions remain open during ischemic conditions." The Journal of neuroscience : the official journal of the Society for Neuroscience. 1998 Apr 1; 18(7):2520-37.
Pincus DW, Goodman RR, Fraser RA, Nedergaard M, Goldman SA. "Neural stem and progenitor cells: a strategy for gene therapy and brain repair." Neurosurgery. 1998 Apr; 42(4):858-67; discussion 867-8.
Cotrina ML, Lin JH, Alves-Rodrigues A, Liu S, Li J, Azmi-Ghadimi H, Kang J, Naus CC, Nedergaard M. "Connexins regulate calcium signaling by controlling ATP release." Proceedings of the National Academy of Sciences of the United States of America. 1998 95(26):15735-40.
Kang J, Jiang L, Goldman SA, Nedergaard M. "Astrocyte-mediated potentiation of inhibitory synaptic transmission." Nature neuroscience. 1998 1(8):683-92.
1997
Wang Z, Tymianski M, Jones OT, Nedergaard M. "Impact of cytoplasmic calcium buffering on the spatial and temporal characteristics of intercellular calcium signals in astrocytes." The Journal of neuroscience : the official journal of the Society for Neuroscience. 1997 Oct 1; 17(19):7359-71.
Rawanduzy A, Hansen A, Hansen TW, Nedergaard M. "Effective reduction of infarct volume by gap junction blockade in a rodent model of stroke." Neurosurgical focus. 1997 May 15; 2(5):E1; discussion 1 p following E1.
Goldman SA, Nedergaard M, Crystal RG, Fraser RA, Goodman R, Harrison-Restelli C, Jiang J, Keyoung HM, Leventhal C, Pincus DW, Shahar A, Wang S. "Neural precursors and neuronal production in the adult mammalian forebrain." Annals of the New York Academy of Sciences. 1997 835:30-55.
Rawanduzy A, Hansen A, Hansen TW, Nedergaard M. "Effective reduction of infarct volume by gap junction blockade in a rodent model of stroke." Journal of neurosurgery. 1997 87(6):916-20.
Pincus DW, Harrison-Restelli C, Barry J, Goodman RR, Fraser RA, Nedergaard M, Goldman SA. "In vitro neurogenesis by adult human epileptic temporal neocortex." Clinical neurosurgery. 1997 44:17-25.
1996
Goldman SA, Williams S, Barami K, Lemmon V, Nedergaard M. "Transient coupling of Ng-CAM expression to NgCAM-dependent calcium signaling during migration of new neurons in the adult songbird brain." Molecular and cellular neurosciences. 1996 Jan; 7(1):29-45.
Nedergaard M. "Spreading depression as a contributor to ischemic brain damage." Advances in neurology. 1996 71:75-83; discussion 83-4.
1995
Nedergaard M. "Intracellular Ca2+ transients evoked by lactic acid in cultured mammalian neurons." The American journal of physiology. 1995 Feb; 268(2 Pt 2):R506-13.
Nedergaard M, Cooper AJ, Goldman SA. "Gap junctions are required for the propagation of spreading depression." Journal of neurobiology. 1995 28(4):433-44.
1994
Makar TK, Nedergaard M, Preuss A, Hertz L, Cooper AJ. "Glutamine transaminase K and omega-amidase activities in primary cultures of astrocytes and neurons and in embryonic chick forebrain: marked induction of brain glutamine transaminase K at time of hatching." Journal of neurochemistry. 1994 May; 62(5):1983-8.
Nedergaard M. "Direct signaling from astrocytes to neurons in cultures of mammalian brain cells." Science. 1994 Mar 25; 263(5154):1768-71.
Makar TK, Nedergaard M, Preuss A, Gelbard AS, Perumal AS, Cooper AJ. "Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain."Journal of neurochemistry. 1994 Jan; 62(1):45-53.
Kirschenbaum,B., Nedergaard,M., Preuss,A., Barami,K., Fraser,R. A., Goldman,S. A. "In vitro neuronal production and differentiation by precursor cells derived from the adult human forebrain." Cereb.Cortex. 1994; 4: 576-589.
1993
Nedergaard M, Goldman SA. "Carrier-mediated transport of lactic acid in cultured neurons and astrocytes." The American journal of physiology. 1993 Aug; 265(2 Pt 2):R282-9.
Nedergaard M, Hansen AJ. "Characterization of cortical depolarizations evoked in focal cerebral ischemia." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 1993 Jul; 13(4):568-74.
1992
Goldman SA, Nedergaard M. "Newly generated neurons of the adult songbird brain become functionally active in long-term culture." Brain research. Developmental brain research. 1992 Aug 21; 68(2):217-23.
1991
Nedergaard M, Goldman SA, Desai S, Pulsinelli WA. "Acid-induced death in neurons and glia." The Journal of neuroscience : the official journal of the Society for Neuroscience. 1991 Aug; 11(8):2489-97.
1991
Nedergaard M, Kraig RP, Tanabe J, Pulsinelli WA. "Dynamics of interstitial and intracellular pH in evolving brain infarct." The American journal of physiology. 1991 Mar; 260(3 Pt 2):R581-8.
1990
Nedergaard M, Desai S, Pulsinelli W. "Dicarboxy-dichlorofluorescein: a new fluorescent probe for measuring acidic intracellular pH." Analytical biochemistry. 1990 May 15; 187(1):109-14.
Jakobsen J, Nedergaard M, Aarslew-Jensen M, Diemer NH. "Regional brain glucose metabolism and blood flow in streptozocin-induced diabetic rats." Diabetes. 1990 Apr; 39(4):437-40.
1988
Nedergaard M, Diemer NH. "Experimental cerebral ischemia: barbiturate resistant increase in regional glucose utilization." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 1988 Oct; 8(5):763-6.
Nedergaard M, Hansen AJ. "Spreading depression is not associated with neuronal injury in the normal brain." Brain research. 1988 May 24; 449(1-2):395-8.
Sillesen H, Nedergaard M, Schroeder T, Buchardt Hansen HJ. "Middle cerebral artery occlusion in presence of low perfusion pressure increases infarct size in rats." Neurological research. 1988 Mar; 10(1):61-3.
Nedergaard M. "Mechanisms of brain damage in focal cerebral ischemia." Acta neurologica Scandinavica. 1988 Feb; 77(2):81-101.
Nedergaard M, Jakobsen J, Diemer NH. "Autoradiographic determination of cerebral glucose content, blood flow, and glucose utilization in focal ischemia of the rat brain: influence of the plasma glucose concentration." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 1988 Feb; 8(1):100-8.
Hansen AJ, Nedergaard M. "Brain ion homeostasis in cerebral ischemia." Neurochemical pathology. 1988 9:195-209.
1987
Nedergaard M. "Transient focal ischemia in hyperglycemic rats is associated with increased cerebral infarction." Brain research. 1987 Apr 7; 408(1-2):79-85.
Nedergaard M, Gjedde A, Diemer NH. "Hyperglycaemia protects against neuronal injury around experimental brain infarcts." Neurological research. 1987 9(4):241-4.
Nedergaard M, Diemer NH. "Focal ischemia of the rat brain, with special reference to the influence of plasma glucose concentration." Acta neuropathologica. 1987 73(2):131-7.
Nedergaard M. "Neuronal injury in the infarct border: a neuropathological study in the rat." Acta neuropathologica. 1987 73(3):267-74.
1986
Nedergaard M, Astrup J. "Infarct rim: effect of hyperglycemia on direct current potential and [14C]2-deoxyglucose phosphorylation." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 1986 Oct; 6(5):607-15.
Nedergaard M, Gjedde A, Diemer NH. "Focal ischemia of the rat brain: autoradiographic determination of cerebral glucose utilization, glucose content, and blood flow." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 1986 Aug; 6(4):414-24.
Nedergaard M, Vorstrup S, Astrup J. "Cell density in the border zone around old small human brain infarcts." Stroke; a journal of cerebral circulation. 1986 17(6):1129-37.
1983
Nedergaard M, Egeberg J, Kromann H. "Irradiation protects against pancreatic islet degeneration and hyperglycaemia following streptozotocin treatment of mice." Diabetologia. 1983 May; 24(5):382-6.
Nedergaard M, Klinken L, Paulson OB. "Secondary brain stem hemorrhage in stroke." Stroke; a journal of cerebral circulation. 1983 14(4):501-5.
1982
Kromann H, Christy M, Lernmark A, Nedergaard M, Nerup J. "The low dose streptozotocin murine model of type 1 (insulin-dependent) diabetes mellitus: studies in vivo and in vitro of the modulating effect of sex hormones." Diabetologia. 1982 Mar; 22(3):194-8.

Books

2012
Lovatt, D., Nedergaard, M.. "Transcriptome Analysis of Astrocytes". Neuroglia. H. Kettenmann and B. R. Ransom. New York: Oxford Univ. Press, 2012. 347-357
2009
Wang, X., Takano, T., Nedergaard, M.. "Astrocytic Ca2+ Signaling: Mechanism and implications for functional brain imaging". Dynamic Brain Imaging. F. Hyder. : Humana Press, 2009. 93-109
2008
Cotrina, M., Nedergaard, M.. "Purinergic regulation of calcium waves". Encyclopedia of Neuroscience. : Springer Berlin Heidelberg, 2008.
2006
Kang, J., Nedergaard, M.. "Imaging astrocytes in acute brain slices". Imaging structure and function in the nervous system, 2th edition. R. Yuste, F. Lanni, A. Konnerth. : Cold Spring Harbor Laboratory Press, 2006.
Dermietzel, R.; Spray, D.C.; Nedergaard, M.;. Blood-Brain Barriers: From Ontogeny to Artificial Interfaces. Dermietzel, R.; Spray, D.C.; Nedergaard, M.;. Weinheim, Germany: Wiley-VCH, 2006.
2005
Cotrina, M.L.; Nedergaard, M.. "Intracellular Calcium Control Mechanisms in Glia". Neuroglia. Kettenmann, H.; Ransom, B.R.. New York: Oxford University Press, 2005. 229-240
2002
Lin, J.; Nedergaard, M.. "Astrocytes in ischemic stroke". Cerebrovascular Disease: 22nd Princeton Conference. Chan, P.. New York: Cambridge University Press, 2002. 113-125
Kang, J.; Nedergaard, M.. "Astrocytes as an intermediary in activity-dependent modulation of inhibitory synaptic transmission in hippocampus". The Tripartite Synapse: Glia in Synaptic Transmission. Volterra, A.; Magistretti, P.; Haydon, P.. New York: Oxford University Press, 2002.
2000
Kang, J.; Nedergaard, M.. "Imaging Astrocytes in Acute Brain Slices". Imaging Structure and Function in the Nervous System. R. Yuste; F. Lanni; A. Konnerth. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 2000. 421-442
1998
Back, T.; Nedergaard M.; Ginsberg., M.D.. "Pathophysiology of Focal Stroke". Cerebrovascular Disease: Pathophysiology, Diagnosis, and Management. M.D. Ginsberg and J. Bogousslavsky. Malden MA: Blackwell Science, 1998. 276-286
1997
Pincus, D.; Harrison, C.; Barry, J.; Goodman, R.; Fraser, R.; Nedergaard, M.; Goldman, S.A.. "In Vitro Neurogenesis by Adult Human Epileptic Temporal Neocortex". Clinical Neurosurgery: Proceedings of the Congress of Neurological Surgeons. Baltimore: Williams & Wilkins, 1997. 17-25
1996
Nedergaard, M.. "Spreading depression as a contributor to ischemic brain damage". Advances in Neurology. B.K. Siesjo and T. Wieloch. New York: Lippincott-Raven, 1996. 75-85
Nedergaard M.; Goldman, S.A.. "Spreading Depression- A Gap Junction Mediated Event?". Gap Junctions in the Nervous System. D.C. Spray; R. Dermietzel. Georgetown, TX: R.G. Landes Company, 1996. 75-84
1989
Nedergaard M.; Diemer, N. H.. "Hypoglycemia Reduces Infarct Size in Experimental Focal Ischemia. The Influence of Plasma Glucose on Ischemic Brain Damage.". Cerebrovascular Diseases. M. Ginsberg and W. Dalton Dietrich. New York: Raven Press, 1989. 259-264
1985
Nedergaard, M.; Klinken, L.; Astrup, J.. "Is There Reduced Neuron Density in the CT Normal Borders of Chronic Brain Infarct". Brain Ischemia: Medical and Surgical Therapy and Rehabilitation. New York: Raven Press, 1985. 57-61
Nedergaard, M.; Gjedde, A.; Diemer, N.H.. "Experimental Stroke: Effects of Hyperglycemia". Brain Ischemia: Medical and Surgical Therapy and Rehabilitation. Fleschi, C.. New York: Raven Press, 1985. 47-53
1984
Nedergaard, M.; Klinken, L.; Astrup, J.. "Cell Density in the Surroundings of Minor and Major Chronic Brain Infarcts". Microsurgical Anastomosis for Cerebral Ischemia. Spetzler, R.. : Unknown, 1984. 72-81