Research at the Center for Translational Neuromedicine
Research Areas
Short descriptions of the the different laboratories
The Nedergaard Laboratory
The basic biology of glial cells in the CNS and the role of astrocytes in several neurological diseases, including stroke, spinal cord injury, epilepsy, tremor, and ALS. Research is aimed at defining new strategies for the treatment of neurological diseases that target astrocytic dysfunction.
The Goldman Laboratory
Identify the expression patterns of the major categories of stem and progenitor cells of the adult human brain and to use that information to define the signaling pathways that distinguish one progenitor from another, as well as those that distinguish brain tumor stem and progenitor cells from their normal counterparts.
The Hirase Laboratory
The Hirase Laboratory investigates how astrocytes regulate ions in the brain to shape neuronal signaling, sleep rhythms, and vascular dynamics. By exploring these fundamental processes — and how they break down in neurological disease — the lab seeks new insights into brain health and disorder
The Untiet Laboratory
The Untiet Laboratory investigates how astrocytes orchestrate ionic homeostasis in the brain, modulating neuronal excitability, sleep rhythms, and vascular function. By uncovering how disruptions in astrocyte-driven ion balance contribute to neurological disease, the lab seeks to illuminate novel avenues for understanding and treating brain disorders.
The Kaag Rasmussen Laboratory
The Kaag-Rasmussen Laboratory explores how dynamic cellular processes and ion regulation in the brain influence neuronal signaling, network stability, and brain health. By combining advanced imaging, electrophysiology, and molecular tools, the lab aims to unravel how astrocytes and other glial cells contribute to maintaining homeostasis — and how disturbances in these mechanisms underlie neurological and psychiatric disorders.
