Physiology of astroglia
Research output: Contribution to journal › Review › Research › peer-review
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Physiology of astroglia. / Verkhratsky, Alexei; Nedergaard, Maiken.
In: Physiological Reviews, Vol. 98, No. 1, 2018, p. 239-389.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Physiology of astroglia
AU - Verkhratsky, Alexei
AU - Nedergaard, Maiken
PY - 2018
Y1 - 2018
N2 - Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in morphological appearance; they express a multitude of receptors, channels, and membrane transporters. This complement underlies their remarkable adaptive plasticity that defines the functional maintenance of the CNS in development and aging. Astrocytes are tightly integrated into neural networks and act within the context of neural tissue; astrocytes control homeostasis of the CNS at all levels of organization from molecular to the whole organ.
AB - Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in morphological appearance; they express a multitude of receptors, channels, and membrane transporters. This complement underlies their remarkable adaptive plasticity that defines the functional maintenance of the CNS in development and aging. Astrocytes are tightly integrated into neural networks and act within the context of neural tissue; astrocytes control homeostasis of the CNS at all levels of organization from molecular to the whole organ.
U2 - 10.1152/physrev.00042.2016
DO - 10.1152/physrev.00042.2016
M3 - Review
C2 - 29351512
AN - SCOPUS:85045955723
VL - 98
SP - 239
EP - 389
JO - Physiological Reviews
JF - Physiological Reviews
SN - 0031-9333
IS - 1
ER -
ID: 209804596