Physiology of astroglia

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Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in morphological appearance; they express a multitude of receptors, channels, and membrane transporters. This complement underlies their remarkable adaptive plasticity that defines the functional maintenance of the CNS in development and aging. Astrocytes are tightly integrated into neural networks and act within the context of neural tissue; astrocytes control homeostasis of the CNS at all levels of organization from molecular to the whole organ.

Original languageEnglish
JournalPhysiological Reviews
Volume98
Issue number1
Pages (from-to)239-389
Number of pages151
ISSN0031-9333
DOIs
Publication statusPublished - 2018

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