Physiology of Astroglia

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Standard

Physiology of Astroglia. / Verkhratsky, Alexei; Parpura, Vladimir; Vardjan, Nina; Zorec, Robert.

Neuroglia in Neurodegenerative Diseases. ed. / Alexei Verkhratsky; Margaret S. Ho; Robert Zorec; Vladimir Parpura. Springer, 2019. p. 45-91 (Advances in Experimental Medicine and Biology, Vol. 1175).

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Harvard

Verkhratsky, A, Parpura, V, Vardjan, N & Zorec, R 2019, Physiology of Astroglia. in A Verkhratsky, MS Ho, R Zorec & V Parpura (eds), Neuroglia in Neurodegenerative Diseases. Springer, Advances in Experimental Medicine and Biology, vol. 1175, pp. 45-91. https://doi.org/10.1007/978-981-13-9913-8_3

APA

Verkhratsky, A., Parpura, V., Vardjan, N., & Zorec, R. (2019). Physiology of Astroglia. In A. Verkhratsky, M. S. Ho, R. Zorec, & V. Parpura (Eds.), Neuroglia in Neurodegenerative Diseases (pp. 45-91). Springer. Advances in Experimental Medicine and Biology Vol. 1175 https://doi.org/10.1007/978-981-13-9913-8_3

Vancouver

Verkhratsky A, Parpura V, Vardjan N, Zorec R. Physiology of Astroglia. In Verkhratsky A, Ho MS, Zorec R, Parpura V, editors, Neuroglia in Neurodegenerative Diseases. Springer. 2019. p. 45-91. (Advances in Experimental Medicine and Biology, Vol. 1175). https://doi.org/10.1007/978-981-13-9913-8_3

Author

Verkhratsky, Alexei ; Parpura, Vladimir ; Vardjan, Nina ; Zorec, Robert. / Physiology of Astroglia. Neuroglia in Neurodegenerative Diseases. editor / Alexei Verkhratsky ; Margaret S. Ho ; Robert Zorec ; Vladimir Parpura. Springer, 2019. pp. 45-91 (Advances in Experimental Medicine and Biology, Vol. 1175).

Bibtex

@inbook{15dcf2aa5b9d40fa94318ab9d8fb1e26,
title = "Physiology of Astroglia",
abstract = "Astrocytes are principal cells responsible for maintaining the brain homeostasis. Additionally, these glial cells are also involved in homocellular (astrocyte-astrocyte) and heterocellular (astrocyte-other cell types) signalling and metabolism. These astroglial functions require an expression of the assortment of molecules, be that transporters or pumps, to maintain ion concentration gradients across the plasmalemma and the membrane of the endoplasmic reticulum. Astrocytes sense and balance their neurochemical environment via variety of transmitter receptors and transporters. As they are electrically non-excitable, astrocytes display intracellular calcium and sodium fluctuations, which are not only used for operative signalling but can also affect metabolism. In this chapter we discuss the molecules that achieve ionic gradients and underlie astrocyte signalling.",
keywords = "Astrocytes, Brain homoeostasis, Ca signalling, Ion channels, Na signalling, Neurotransmitter receptors, SLC transporters",
author = "Alexei Verkhratsky and Vladimir Parpura and Nina Vardjan and Robert Zorec",
year = "2019",
doi = "10.1007/978-981-13-9913-8_3",
language = "English",
isbn = "978-981-13-9912-1",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer",
pages = "45--91",
editor = "Alexei Verkhratsky and Ho, {Margaret S.} and Robert Zorec and Vladimir Parpura",
booktitle = "Neuroglia in Neurodegenerative Diseases",
address = "Switzerland",

}

RIS

TY - CHAP

T1 - Physiology of Astroglia

AU - Verkhratsky, Alexei

AU - Parpura, Vladimir

AU - Vardjan, Nina

AU - Zorec, Robert

PY - 2019

Y1 - 2019

N2 - Astrocytes are principal cells responsible for maintaining the brain homeostasis. Additionally, these glial cells are also involved in homocellular (astrocyte-astrocyte) and heterocellular (astrocyte-other cell types) signalling and metabolism. These astroglial functions require an expression of the assortment of molecules, be that transporters or pumps, to maintain ion concentration gradients across the plasmalemma and the membrane of the endoplasmic reticulum. Astrocytes sense and balance their neurochemical environment via variety of transmitter receptors and transporters. As they are electrically non-excitable, astrocytes display intracellular calcium and sodium fluctuations, which are not only used for operative signalling but can also affect metabolism. In this chapter we discuss the molecules that achieve ionic gradients and underlie astrocyte signalling.

AB - Astrocytes are principal cells responsible for maintaining the brain homeostasis. Additionally, these glial cells are also involved in homocellular (astrocyte-astrocyte) and heterocellular (astrocyte-other cell types) signalling and metabolism. These astroglial functions require an expression of the assortment of molecules, be that transporters or pumps, to maintain ion concentration gradients across the plasmalemma and the membrane of the endoplasmic reticulum. Astrocytes sense and balance their neurochemical environment via variety of transmitter receptors and transporters. As they are electrically non-excitable, astrocytes display intracellular calcium and sodium fluctuations, which are not only used for operative signalling but can also affect metabolism. In this chapter we discuss the molecules that achieve ionic gradients and underlie astrocyte signalling.

KW - Astrocytes

KW - Brain homoeostasis

KW - Ca signalling

KW - Ion channels

KW - Na signalling

KW - Neurotransmitter receptors

KW - SLC transporters

U2 - 10.1007/978-981-13-9913-8_3

DO - 10.1007/978-981-13-9913-8_3

M3 - Book chapter

C2 - 31583584

AN - SCOPUS:85072916918

SN - 978-981-13-9912-1

T3 - Advances in Experimental Medicine and Biology

SP - 45

EP - 91

BT - Neuroglia in Neurodegenerative Diseases

A2 - Verkhratsky, Alexei

A2 - Ho, Margaret S.

A2 - Zorec, Robert

A2 - Parpura, Vladimir

PB - Springer

ER -

ID: 231243566