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The Alzheimer's disease 5xFAD mouse model is best suited to investigate pretargeted imaging approaches beyond the blood-brain barrier
Lopes van den Broek, S. I., Sehlin, D., Andersen, Jens Velde, Aldana, Blanca, Beschorner, Natalie, Nedergaard, Maiken, Knudsen, Gitte Moos, Syvanen, S. & Herth, Matthias Manfred, 2023, In: Frontiers in Nuclear Medicine. 2, 7 p., 1001722.Research output: Contribution to journal › Journal article › Research › peer-review
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Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier
Lou, N., Takano, T., Pei, Y., L R Xavier, Anna , Goldman, Steven Alan & Nedergaard, Maiken, 26 Jan 2016, In: National Academy of Sciences. Proceedings. 113, 4, p. 1074-1079 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Understanding the functions and relationships of the glymphatic system and meningeal lymphatics
Louveau, A., Plog, B. A., Antila, S., Alitalo, K., Nedergaard, Maiken & Kipnis, J., 1 Sep 2017, In: The Journal of Clinical Investigation. 127, 9, p. 3210-3219 10 p.Research output: Contribution to journal › Review › Research › peer-review
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ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update
Lovell-Badge, R., Anthony, E., Barker, R. A., Bubela, T., Brivanlou, A. H., Carpenter, M., Charo, R. A., Clark, A., Clayton, E., Cong, Y., Daley, G. Q., Fu, J., Fujita, M., Greenfield, A., Goldman, S. A., Hill, L., Hyun, I., Isasi, R., Kahn, J., Kato, K. & 27 others, , 2021, In: Stem Cell Reports. 16, 6, p. 1398-1408 11 p.Research output: Contribution to journal › Review › Research › peer-review
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Glymphatic clearance controls state-dependent changes in brain lactate concentration
Lundgaard, I., Lu, M. L., Yang, E., Peng, W., Mestre, H., Hitomi, E., Deane, R. & Nedergaard, Maiken, Jun 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 6, p. 2112-2124 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Direct neuronal glucose uptake Heralds activity-dependent increases in cerebral metabolism
Lundgaard, I., Li, B., Xie, L., Kang, H., Sanggaard, S., Haswell, J. D. R., Sun, W., Goldman, S., Blekot, S., Nielsen, Michael Lund, Takano, T., Deane, R. & Nedergaard, Maiken, 2015, In: Nature Communications. 6, 12 p., 6807.Research output: Contribution to journal › Journal article › Research › peer-review
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Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function
Lundgaard, I., Wang, W., Eberhardt, A., Vinitsky, H. S., Reeves, B. C., Peng, S., Lou, N., Hussain, R. & Nedergaard, Maiken, 2018, In: Scientific Reports. 8, 1, 16 p., 2246.Research output: Contribution to journal › Journal article › Research › peer-review
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Psilocybin-induced reduction in chronic cluster headache attack frequency correlates with changes in hypothalamic functional connectivity
Madsen, M. K., Petersen, A. S., Stenbæk, Dea Siggaard, Sorensen, I. M., Schionning, H., Fjeld, T., Nykjaer, C., Larsen, S. M. U., Grzywacz, M., Mathiesen, T., Klausen, I., Hansen, O. O., Brendstrup-Brix, K., Linnet, Kristian, Johansen, Sys Stybe, Fisher, P. M., Jensen, Rasmus Herlo Beenfeldt, Knudsen, Gitte Moos & Madsen, M. K., 2022, medRxiv, 17 p.Research output: Working paper › Preprint › Research
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Derivation of telencephalic oligodendrocyte progenitors from human pluripotent stem cells
Major, T., Powers, A. & Tabar, V., Nov 2016, In: Current Protocols in Stem Cell Biology. 39, 1, p. 1H.10.1-1H.10.23 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human Glial Chimeric Mice to Define the Role of Glial Pathology in Human Disease
Mariani, J. N., Zou, L. & Goldman, Steven Alan, 2019, Oligodendrocytes. Springer, Vol. 1936. p. 311-331 21 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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TUBE project: Transport-derived ultrafines and the brain effects
Martikainen, M. V., Aakko-Saksa, P., Broek, L. V. D., Cassee, F. R., Carare, R. O., Chew, S., Dinnyes, A., Giugno, R., Kanninen, K. M., Malm, T., Muala, A., Nedergaard, M., Oudin, A., Oyola, P., Pfeiffer, T. V., Rönkkö, T., Saarikoski, S., Sandström, T., Schins, R. P. F., Topinka, J. & 4 others, , 2022, In: International Journal of Environmental Research and Public Health. 19, 1, 14 p., 311.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disruption of Semantic Network in Mild Alzheimer's Disease Revealed by Resting-State fMRI
Mascali, D., DiNuzzo, M., Serra, L., Mangia, S., Maraviglia, B., Bozzali, M. & Giove, F., 2018, In: Neuroscience. 371, p. 38-48 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice
Mathiesen, B. K., Miyakoshi, L. M., Cederroth, C. R., Tserga, E., Versteegh, C., Bork, Peter Aleksander Rousing, Hauglund, Natalie Linea, Gomolka, Ryszard Stefan, Mori, Yuki, Edvall, N. K., Rouse, S., Møllgård, Kjeld, Holt, J. R., Nedergaard, Maiken & Canlon, B., 2023, In: Science Translational Medicine. 15, 702, 13 p., eabq3916.Research output: Contribution to journal › Journal article › Research › peer-review
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The Brain's Glymphatic System: Current Controversies
Mestre, H., Mori, Yuki & Nedergaard, Maiken, 2020, In: Trends in Neurosciences. 43, 7, p. 458-466 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Cerebrospinal fluid influx drives acute ischemic tissue swelling
Mestre, H., Du, T., Sweeney, A. M., Liu, G., Samson, A. J., Peng, W., Mortensen, K. N., Stæger, F. F., Bork, P. A. R., Bashford, L., Toro, E. R., Tithof, J., Kelley, D. H., Thomas, J. H., Hjorth, P. G., Martens, E. A., Mehta, R. I., Solis, O., Blinder, P., Kleinfeld, D. & 3 others, , 2020, In: Science. 367, 6483, 8 p., eaaw7462.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aquaporin-4-dependent glymphatic solute transport in the rodent brain
Mestre, H., Hablitz, L. M., Xavier, A. L. R., Feng, W., Zou, W., Pu, T., Monai, H., Murlidharan, G., Rivera, R. M. C., Simon, M. J., Pike, M. M., Pla, V., Du, T., Kress, B. T., Wang, X., Plog, B. A., Thrane, A. S., Lundgaard, I., Abe, Y., Yasui, M. & 6 others, , 2018, In: eLife. 7, 31 p., :e40070.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perivascular spaces, glymphatic dysfunction, and small vessel disease
Mestre, H., Kostrikov, S., Mehta, R. I. & Nedergaard, Maiken, 1 Sep 2017, In: Clinical Science. 131, 17, p. 2257-2274 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension
Mestre, H., Tithof, J., Du, T., Song, W., Peng, W., Sweeney, A. M., Olveda, G., Thomas, J. H., Nedergaard, Maiken & Kelley, D. H., 2018, In: Nature Communications. 9, 1, 9 p., 4878.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Periarteriolar spaces modulate cerebrospinal fluid transport into brain and demonstrate altered morphology in aging and Alzheimer’s disease
Mestre, H., Verma, N., Greene, T. D., Lin, L. J. A., Ladron-de-Guevara, A., Sweeney, A. M., Liu, G., Thomas, V. K., Galloway, C. A., de Mesy Bentley, K. L., Nedergaard, Maiken & Mehta, R. I., 2022, In: Nature Communications. 13, 1, 8 p., 3897.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative determination of cellular [Na+] by fluorescence lifetime imaging with CoroNaGreen
Meyer, J., Untiet, Verena, Fahlke, C., Gensch, T. & Rose, C. R., 2019, In: Journal of General Physiology. 151, 11, p. 1319-1331Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Surface periarterial spaces of the mouse brain are open, not porous
Min Rivas, F., Liu, J., Martell, B. C., Du, T., Mestre, H., Nedergaard, Maiken, Tithof, J., Thomas, J. H. & Kelley, D. H., 2020, In: Journal of the Royal Society, Interface. 17, 172, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcranial Direct Current Stimulation (tDCS Induces Adrenergic Receptor-Dependent Microglial Morphological Changes in Mice
Mishima, T., Nagai, T., Yahagi, K., Akther, S., Oe, Y., Monai, H., Kohsaka, S. & Hirase, Hajime, 2019, In: eNeuro. 6, 5, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The state of brain activity modulates cerebrospinal fluid transport
Miyakoshi, L. M., Stæger, Frederik Filip Vinggaard, Li, Q., Pan, C., Xie, L., Kang, H., Pavan, C., Dang, J., Sun, Q., Ertürk, A. & Nedergaard, Maiken, 2023, In: Progress in Neurobiology. 229, 11 p., 102512.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Glymphatic System (En)during Inflammation
Mogensen, F. L., Delle, Christine & Nedergaard, Maiken, 2021, In: International Journal of Molecular Sciences. 22, 14, 20 p., 7491.Research output: Contribution to journal › Review › Research › peer-review
- Published
Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis
Mohanty, T., Fisher, J., Bakochi, A., Neumann, A., Cardoso, J. F. P., Karlsson, C. A. Q., Pavan, C., Lundgaard, I., Nilson, B., Reinstrup, P., Bonnevier, J., Cederberg, D., Malmström, J., Bentzer, P. & Linder, A., 2019, In: Nature Communications. 10, 13 p., 1667.Research output: Contribution to journal › Journal article › Research › peer-review
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SPECT imaging of the glymphatic pathway with In-111-labeled ovalbumin in the rat brain
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In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy
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Understanding the functions and relationships of the glymphatic system and meningeal lymphatics
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Remyelination in the Central Nervous System
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Glymphatic fluid transport is suppressed by the aquaporin-4 inhibitor AER-271
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The glymphatic system and Amyotrophic lateral sclerosis
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