Center for Translational Neuromedicine

  1. Published

    Derivation of telencephalic oligodendrocyte progenitors from human pluripotent stem cells

    Major, T., Powers, A. & Tabar, V., Nov 2016, In: Current Protocols in Stem Cell Biology. 39, 1, p. 1H.10.1-1H.10.23 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Design of gadoteridol-loaded cationic liposomal adjuvant CAF01 for MRI of lung deposition of intrapulmonary administered particles

    Thakur, A., Rose, F., Ansari, S. R., Koch, P., Martini, V., Ovesen, S. L., Quistorff, B., Maritim, S., Hyder, F., Andersen, Peter, Christensen, D., Mori, Yuki & Foged, Camilla, 2019, In: Molecular Pharmaceutics. 16, 11, p. 4725-4737 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Determination of intracellular chloride concentration in glial cell types using fluorescence lifetime imaging microscopy (FLIM)

    Engels, M., Untiet, Verena, Gensch, T., Kovermann, P. & Fahlke, C., 2019. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  4. Published

    Development of 11C-labeled CRANAD-102 for positron emission tomography imaging of soluble Aβ-species

    Staudt, Markus, Shalgunov, Vladimir, Nedergaard, Maiken & Herth, Matthias Manfred, 2023, In: Journal of Labelled Compounds and Radiopharmaceuticals. 66, 12, p. 393-399

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Development of the entorhinal cortex occurs via parallel lamination during neurogenesis

    Liu, Y., Bergmann, T., Mori, Yuki, Peralvo Vidal, Juan Miguel, Pihl, M., Vasistha, Navneet A, Thomsen, Preben Dybdahl, Seemann, Ernst Stefan, Gorodkin, Jan, Hyttel, P., Khodosevich, Konstantin, Witter, M. P. & Hall, Vanessa Jane, 2021, In: Frontiers in Neuroanatomy. 15, 19 p., 663667.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Developmental trajectory of episodic-like memory in rats

    Asiminas, Antonios, Lyon, S. A., Langston, R. F. & Wood, E. R., 2022, In: Frontiers in Behavioral Neuroscience. 16, 20 p., 969871.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs

    Lilius, T. O., Blomqvist, K., Hauglund, Natalie Linea, Liu, G., Stæger, Frederik Filip Vinggaard, Baerentzen, S., Du, T., Ahlstrom, F., Backman, J. T., Kalso, E. A., Rauhala, P. V. & Nedergaard, Maiken, 2019, In: Journal of Controlled Release. 304, p. 29-38 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Direct Measurement of Cerebrospinal Fluid Production in Mice

    Liu, G., Mestre, H., Sweeney, A. M., Sun, Q., Weikop, Pia, Du, T. & Nedergaard, Maiken, 2020, In: Cell Reports. 33, 12, 13 p., 108524.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons

    Nolbrant, S., Giacomoni, J., Hoban, D. B., Bruzelius, A., Birtele, M., Chandler-Militello, D., Pereira, M., Ottosson, D. R., Goldman, Steven Alan & Parmar, M., 2020, In: Stem Cell Reports. 15, 4, p. 869-882 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Direct conversion of hESC-derived glial progenitors into midbrain dopaminergic neurons

    Nolbrant, S., Hoban, D., Giacomoni, J., Ottosson, D. R., Goldman, Steven Alan & Parmar, M., 2019, In: Glia. 67, S1, p. E662-E663 2 p., T16-015B.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  11. Published

    Direct neuronal glucose uptake Heralds activity-dependent increases in cerebral metabolism

    Lundgaard, I., Li, B., Xie, L., Kang, H., Sanggaard, S., Haswell, J. D. R., Sun, W., Goldman, S., Blekot, S., Nielsen, Michael Lund, Takano, T., Deane, R. & Nedergaard, Maiken, 2015, In: Nature Communications. 6, 12 p., 6807.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Disruption of Semantic Network in Mild Alzheimer's Disease Revealed by Resting-State fMRI

    Mascali, D., DiNuzzo, M., Serra, L., Mangia, S., Maraviglia, B., Bozzali, M. & Giove, F., 2018, In: Neuroscience. 371, p. 38-48 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance

    Oe, Y., Wang, Xiaowen, Patriarchi, T., Konno, A., Ozawa, K., Yahagi, K., Hirai, H., Tian, L., McHugh, T. J. & Hirase, Hajime, 2020, In: Nature Communications. 11, 1, 15 p., 471.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain?

    Oberheim Bush, N. A. & Nedergaard, Maiken, Sep 2017, In: Neurochemical Research. 42, 9, p. 2577-2587 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Does Global Astrocytic Calcium Signaling Participate in Awake Brain State Transitions and Neuronal Circuit Function?

    Kjærby, Celia, Rasmussen, R., Andersen, Mie & Nedergaard, Maiken, Jun 2017, In: Neurochemical Research. 42, 6, p. 1810-1822 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Does Long-Duration Exposure to Microgravity Lead to Dysregulation of the Brain and Ocular Glymphatic Systems?

    Wostyn, P., Mader, T. H., Gibson, C. R. & Nedergaard, Maiken, 2022, In: Eye and Brain. 14, p. 49-58 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Donor cell memory confers a metastable state of directly converted cells

    Kim, K. P., Li, C., Bunina, D., Jeong, H. W., Ghelman, J., Yoon, J., Shin, B., Park, H., Han, D. W., Zaugg, J. B., Kim, J., Kuhlmann, T., Adams, R. H., Noh, K. M., Goldman, Steven Alan & Schöler, H. R., 2021, In: Cell Stem Cell. 28, 7, p. 1291-1306.e10 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Dorsal striatal dopamine induces fronto-cortical hypoactivity and attenuates anxiety and compulsive behaviors in rats

    Casado-Sainz, A., Gudmundsen, F., Baerentzen, S. L., Lange, D., Ringsted, A., Martinez-Tejada, I., Medina, S., Lee, H., Svarer, C., Keller, S. H., Schain, M., Kjærby, Celia, Fisher, P. M., Cumming, P. & Palner, M., 2022, In: Neuropsychopharmacology. 47, p. 454–464 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Dynamic fluctuations of the locus coeruleus-norepinephrine system underlie sleep state transitions

    Kjærby, Celia, Andersen, Mie, Hauglund, Natalie Linea, Ding, F., Wang, W., Xu, Q., Deng, S., Kang, N., Peng, S., Sun, Q., Dall, C., Jørgensen, P. K., Feng, J., Li, Y., Weikop, Pia, Hirase, Hajime & Nedergaard, Maiken, 2 Sep 2020, 1 p.

    Research output: Other contributionResearch

  20. Published

    Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling

    Liu, Z., Osipovitch, M., Benraiss, A., Huynh, N. P. T., Foti, R., Bates, J., Chandler-Militello, D., Findling, R. L., Tesar, P. J., Nedergaard, Maiken, Windrem, M. S. & Goldman, Steven Alan, 2019, In: Cell Reports. 27, 13, p. 3832-3843, e1-e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    EARLY ADDRESS OF POST-TRAUMATIC GLYMPHATIC INSUFFICIENCY REDUCES NEURONAL/GLIAL CELL DEATH AND TISSUE DAMAGES

    Hussain, R., Wang, W. & Nedergaard, Maiken, 2019, In: Journal of Neurotrauma. 36, 13, p. A-101 1 p., B04-05.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  22. Published

    EARLY INTRODUCTION TO HIGH-INTENSITY INTERVAL TRAINING IN STROKE ASSOCIATES WITH SUSTAINED VIGOROUS-INTENSITY ACTIVITY AT LONG-TERM FOLLOW-UP - RESULTS FROM THE HITPALS STUDY

    Krawcyk, R. S., Vinther, A., Petersen, Nicolas Caesar, Faber, Jens, Iversen, Helle Klingenberg, Christensen, T., Lambertsen, K., Klausen, T., Rostrup, E. & Kruuse, Christina Rostrup, 2020, In: International Journal of Stroke. 15, Supplement 1, p. 132 00477 / #2449.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  23. Published

    Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model

    Parka, A., Degel, C., Dreyer, J., Richter, U., Hall, B., Bastlund, J. F., Laursen, B., Nedergaard, Maiken, Sotty, F. & Botta, P., 2023, In: Neurobiology of Disease. 178, 13 p., 106012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Editorial: Role of Astrocytes in Seizures Induced by Traumatic Brain Injury

    Wang, F., Pan, F., Hirase, Hajime & Huang, J. H., 2020, In: Frontiers in Neurology. 11, 604788.

    Research output: Contribution to journalEditorialResearchpeer-review

  25. Published

    Editorial: Sleep and Mood Disorders

    Verkhratsky, A., Nedergaard, Maiken, Steardo, L. & Li, B., 2020, In: Frontiers in Psychiatry. 10, 3 p., 981.

    Research output: Contribution to journalEditorialResearchpeer-review

  26. Published

    Editorial: Neuroglia Molecular Mechanisms in Psychiatric Disorders

    Scuderi, C., Noda, M. & Verkhratsky, A., 2018, In: Frontiers in Molecular Neuroscience. 11, 2 p., 407.

    Research output: Contribution to journalEditorialResearchpeer-review

  27. Published

    Effect of ADHD medication in male C57BL/6J mice performing the rodent Continuous Performance Test

    Caballero-Puntiverio, M., Lerdrup, L. S., Grupe, M., Larsen, C. W., Dietz, Andrea Grostøl & Andreasen T., Jesper, 2019, In: Psychopharmacology. 236, 6, p. 1839-1851 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty

    Thrane, V. R., Thrane, A. S., Bergo, C., Halvorsen, H. & Krohn, J., 2020, In: Journal of Glaucoma. 29, 4, p. 280-286 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Effect of Home-Based High-Intensity Interval Training in Patients With Lacunar Stroke: A Randomized Controlled Trial

    Krawcyk, R. S., Vinther, A., Petersen, Nicolas Caesar, Faber, Jens, Iversen, Helle Klingenberg, Christensen, T., Lambertsen, K. L., Rehman, S., Klausen, T. W., Rostrup, E. & Kruuse, Christina Rostrup, 2019, In: Frontiers in Neurology. 10, 15 p., 664.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Effect of beta-adrenergic antagonists on the risk of alzheimer's disease amongst hypertensive patients: a nation-wide cohort study

    Beaman, E., Bonde, A. N., Larsen, S. M. U., Ozenne, Brice Maxime Hugues, Lohela, T. J., Gislason, Gunnar Hilmar, Knudsen, Gitte Moos & Holst, S. C., 2020, In: European Neuropsychopharmacology. 40, p. S219-S220 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  31. Published

    Effect of sleep deprivation and NREM sleep stage on physiological brain pulsations

    Helakari, H., Järvelä, M., Väyrynen, T., Tuunanen, J., Piispala, J., Kallio, M., Ebrahimi, S. M., Poltojainen, V., Kananen, J., Elabasy, A., Huotari, N., Raitamaa, L., Tuovinen, T., Korhonen, V., Nedergaard, Maiken & Kiviniemi, V., 2023, In: Frontiers in Neuroscience. 17, 17 p., 1275184.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Enriched environment enhances β-adrenergic signaling to prevent microglia inflammation by amyloid-β

    Xu, H., Rajsombath, M. M., Weikop, Pia & Selkoe, D. J., 2018, In: EMBO Molecular Medicine. 10, 9, 17 p., e8931.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Erratum: Two types of muscarinic acetylcholine receptors in Drosophila and other arthropods (Cellular and Molecular Life Sciences (2013) 70 (3231-3242) DOI: 10.1007/s0001801313340))

    Collin, C., Hauser, Frank, Gonzalez De Valdivia, E., Li, S., Reisenberger, J., Carlsen, Eva Maria Meier, Khan, Z., Hansen, N. O., Puhm, F., Søndergaard, Leif, Niemiec, J., Heninger, M., Ren, G. R. & Grimmelikhuijzen, Cornelis (Cok), Nov 2013, In: Cellular and Molecular Life Sciences. 70, 21, p. 4197 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  34. Published

    Erythrocytes Are Oxygen-Sensing Regulators of the Cerebral Microcirculation

    Wei, H. S., Kang, H., Rasheed, I. D., Zhou, S., Lou, N., Gershteyn, A., McConnell, E. D., Wang, Y., Richardson, K. E., Palmer, A. F., Xu, C., Wan, J. & Nedergaard, Maiken, 17 Aug 2016, In: Neuron. 91, 4, p. 851-862 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published
  36. Published

    Estimation of protein intestinal digestibility of feeds by means of three-steps technique

    Cabral, L., Valadares, S., Malafaia, P., Lana, R., da Silva, J., Vieira, R. & Pereira, E., 2001, In: Revista Brasileira de Zootecnia. 30, 2, p. 546-552 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Evolution of Neuroglia

    Verkhratsky, A., Ho, M. S. & Parpura, V., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 15-44 30 p. (Advances in Experimental Medicine and Biology, Vol. 1175).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  38. Published

    Experience-dependent changes in hippocampal spatial activity and hippocampal circuit function are disrupted in a rat model of Fragile X Syndrome

    Asiminas, Antonios, Booker, S. A., Dando, O. R., Kozic, Z., Arkell, D., Inkpen, F. H., Sumera, A., Akyel, I., Kind, P. C. & Wood, E. R., 2022, In: Molecular Autism. 13, 1, 29 p., 49.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Feasibility of IVIM parameters from diffusion-weighted imaging at 11.7T MRI for detecting ischemic changes in common carotid artery occlusion rats

    Fujiwara, S., Mori, Yuki, de la Mora, D. M., Akamatsu, Y., Yoshida, K., Shibata, Y., Masuda, T., Ogasawara, K. & Yoshioka, Y., 2020, In: Scientific Reports. 10, 1, 10 p., 8404.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Fibroblast growth factor 21: an endocrine inhibitor of sugar and alcohol appetite

    Holstein-Rønsbo, Stephanie & Gillum, M. P., 2019, In: The Journal of Physiology. 597, 14, p. 3539-3548 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension

    Mestre, H., Tithof, J., Du, T., Song, W., Peng, W., Sweeney, A. M., Olveda, G., Thomas, J. H., Nedergaard, Maiken & Kelley, D. H., 2018, In: Nature Communications. 9, 1, 9 p., 4878.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Fluid Transport in the Brain

    Rasmussen, Martin Kaag, Mestre, H. & Nedergaard, Maiken, 2022, In: Physiological Reviews. 102, p. 1025-1151 27 p.

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    Focal Solute Trapping and Global Glymphatic Pathway Impairment in a Murine Model of Multiple Microinfarcts

    Wang, M., Ding, F., Deng, S., Guo, X., Wang, W., Iliff, J. J. & Nedergaard, Maiken, 15 Mar 2017, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 37, 11, p. 2870-2877 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    General Pathophysiology of Astroglia

    Verkhratsky, A., Ho, M. S., Vardjan, N., Zorec, R. & Parpura, V., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 149-179 31 p. (Advances in Experimental Medicine and Biology, Vol. 1175).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  45. Published

    Genetic haplotype of the glymphatic-associated water channel aquaporin 4 modulates slow waves in human non-rapid eye movement sleep

    Larsen, S. M. U., Landolt, H. P., Berger, W., Nedergaard, Maiken, Knudsen, Gitte Moos & Holst, S. C., 2019, In: European Neuropsychopharmacology. 29, Supplement 6, p. S563-S564 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  46. Published

    Glia Disease and Repair-Remyelination

    Franklin, R. J. M. & Goldman, Steven Alan, Jul 2015, In: Cold Spring Harbor perspectives in biology. 7, 7, p. 1-28 28 p., a020594.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Glia in Health and Disease

    Ho, M. S., Verkhratsky, A., Duan, S. & Parpura, V., 2019, In: Frontiers in Molecular Neuroscience. 12, 3 p., 63.

    Research output: Contribution to journalEditorialResearchpeer-review

  48. Published

    Glial cells in schizophrenia: a unified hypothesis

    Dietz, Andrea Grostøl, Goldman, Steven Alan & Nedergaard, Maiken, 2020, In: Lancet Psychiatry. 7, 3, p. 272-281 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    Glial evolution as a determinant of human behavior and its disorders

    Goldman, Steven Alan, 2020, In: Annals of the New York Academy of Sciences. 1471, 1, p. 72-85 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published

    Glial progenitor cell-based repair of the dysmyelinated brain: Progression to the clinic

    Goldman, Steven Alan, Mariani, J. N. & Madsen, P. M., 2021, In: Seminars in Cell and Developmental Biology. 116, p. 62-70 9 p.

    Research output: Contribution to journalReviewResearchpeer-review