Center for Translational Neuromedicine

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  1. Published

    Astrogliopathology in the infectious insults of the brain

    Zorec, R., Županc, T. A. & Verkhratsky, A., 2019, In: Neuroscience Letters. 689, p. 56-62 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  2. Published

    Behavioral and biochemical effects of alcohol withdrawal in female C3H/HeNRj and C57BL/6JRj mice

    Tonetto, S., Weikop, Pia, Brudek, T. & Thomsen, M., 2023, In: Frontiers in Behavioral Neuroscience. 17, 18 p., 1143720.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function

    Lundgaard, I., Wang, W., Eberhardt, A., Vinitsky, H. S., Reeves, B. C., Peng, S., Lou, N., Hussain, R. & Nedergaard, Maiken, 2018, In: Scientific Reports. 8, 1, 16 p., 2246.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Biological sex does not predict glymphatic influx in healthy young, middle aged or old mice

    Giannetto, M., Xia, M., Stæger, Frederik Filip Vinggaard, Metcalfe, T., Vinitsky, H. S., Dang, J. A. M. L., L R Xavier, Anna , Kress, B. T., Nedergaard, Maiken & Hablitz, L. M., 2020, In: Scientific Reports. 10, 1, 8 p., 16073.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Biophysical Modeling of Dopaminergic Denervation Landscapes in the Striatum Reveals New Therapeutic Strategy

    Heltberg, Mathias Spliid, Awada, H. N., Lucchetti, Alessandra, Jensen, Mogens Høgh, Dreyer, J. K. & Rasmussen, R. N., 2022, In: eNeuro. 9, 2, 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Birthweight z-score and fat-free mass at birth predict body composition at 3 years in Danish children born from obese mothers

    Berglund, N. R., Lewis, Jack Ivor, Michaelsen, Kim F., Mølgaard, Christian, Renault, Kristina Martha & Carlsen, Eva Maria Meier, 2022, In: Acta Paediatrica. 111, 7, p. 1427-1434 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Blood–brain barrier permeable β-blockers linked to lower risk of Alzheimer’s disease in hypertension

    Beaman, Emily Eufaula, Bonde, A. N., Larsen, S. M. U., Ozenne, Brice Maxime Hugues, Lohela, T. J., Nedergaard, Maiken, Gislason, Gunnar Hilmar, Knudsen, Gitte Moos & Holst, S. C., 2023, In: Brain. 146, 3, p. 1141–1151 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Brain Morphometry and Longitudinal Relaxation Time of Spontaneously Hypertensive Rats (SHRs) in Early and Intermediate Stages of Hypertension Investigated by 3D VFA-SPGR MRI

    Koundal, S., Liu, X., Sanggaard, S., Mortensen, K., Wardlaw, J., Nedergaard, Maiken, Benveniste, H. & Lee, H., 2019, In: Neuroscience. 404, p. 14-26

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Brain Segmentation in Rodent MR-Images Using Convolutional Neural Networks

    Sigurdsson, B., Darkner, Sune, Sommer, Stefan Horst, Mortensen, K. N., Sanggaard, S., Kostrikov, S. & Nedergaard, Maiken, 2018.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  10. Published

    Brain energetics during the sleep-wake cycle

    DiNuzzo, M. & Nedergaard, Maiken, Dec 2017, In: Current Opinion in Neurobiology. 47, p. 65-72 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    Brain lipidomics and neurodevelopmental outcomes in intrauterine growth restricted piglets fed dairy or vegetable fat diets

    Henriksen, Nicole Lind, Asmussen, K. S., Pan, X., Jiang, Pingping, Mori, Yuki, Christiansen, Line Iadsatian, Sprenger, R. R., Ejsing, C. S., Pankratova, Stanislava & Thymann, Thomas, 2022, In: Scientific Reports. 12, 1, 3303.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Brain-specific glycosylation of protein tyrosine phosphatase receptor type Z (PTPRZ) marks a demyelination-associated astrocyte subtype

    Takahashi, K., Kanekiyo, K., Sakuda, K., Muto, Y., Iguchi, M., Matsuda, N., Hashimoto, Y., Kanai, K., Ogawa, H., Hirase, Hajime, Kakita, A., Bizen, N., Takebayashi, H., Kawaguchi, Y., Uzuki, M. & Kitazume, S., 2023, In: Journal of Neurochemistry. 166, 3, 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Branch retinal artery occlusion as a clinical manifestation of hereditary haemorrhagic telangiectasia (Osler-Weber-Rendu syndrome) in pregnancy

    Askim, A. J., Thrane, A. S., Giaever, P., Andersen, R. & Krohn, J., Mar 2018, In: Acta Ophthalmologica. 96, 2, p. 197-199 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection

    Raghunandan, A., Ladron-De-guevara, A., Tithof, J., Mestre, H., Du, T., Nedergaard, Maiken, Thomas, J. H. & Kelley, D. H., 2021, In: eLife. 10, 15 p., e65958.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Butyrate reduction and HDAC4 increase underlie maternal high fructose-induced metabolic dysfunction in hippocampal astrocytes in female rats

    Wu, K. L. H., Liu, W. C., Wu, C. W., Fu, M. H., Huang, H. M., Tain, Y. L., Liang, C. K., Hung, C. Y., Chen, I. C., Hung, P. L., Lin, Y. J. & Hirase, Hajime, 2024, In: Journal of Nutritional Biochemistry. 126, 14 p., 109571.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    CHARACTERIZATION OF A RAT MODEL OF ACUTE BACTERIAL MENINGITIS

    Fisher, J., Pavan, C., Linder, A. & Bentzer, P., 2019, In: Shock. 51, Supplement 1 6S, p. 82 1 p., P89.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  17. Published

    CSF space volumetry using 3D-CISS in Aqp4-deficient mice – quantitative analysis and technical advances

    Gomolka, Ryszard Stefan, Nedergaard, Maiken & Mori, Yuki, 2021, Book of Abstracts ESMRMB 2021 Online 38th Annual Scientific Meeting 7-9 October 2021. Springer, Vol. 34. p. S95-6 2 p. (Magnetic Resonance Materials in Physics, Biology, and Medicine; No. 34).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  18. Published

    Cannula Implantation into the Cisterna Magna of Rodents

    L R Xavier, Anna , Hauglund, Natalie Linea, Holstein-Rønsbo, Stephanie, Li, Q., Sanggaard, S., Lou, N., Lundgaard, I. & Nedergaard, Maiken, 2018, In: Journal of Visualized Experiments. 135, 6 p., e57378.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Cell Therapy for Huntington's Disease: Learning from Failure

    Rosser, A. E., Busse, M., Badin, R. A., Canals, J. M., Wheelock, V., Perrier, A. L., Gray, W., Thompson, L. & Goldman, Steven Alan, 2021, In: Movement Disorders. 36, 3, p. 787-788 2 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  20. Published

    Cell therapy for pediatric disorders of glia

    Albuquerque Osório, M. J. & Goldman, Steven Alan, 2016, Translational Neuroscience: Fundamental Approaches for Neurological Disorders. Springer, p. 275-296 22 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  21. Published

    Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs

    Feng, L., Chao, J., Tian, E., Li, L., Ye, P., Zhang, M., Chen, X., Cui, Q., Sun, G., Zhou, T., Felix, G., Qin, Y., Li, W., Meza, E. D., Klein, J., Ghoda, L., Hu, W., Luo, Y., Dang, W., Hsu, D. & 4 others, Gold, J., Goldman, Steven Alan, Matalon, R. & Shi, Y., 2020, In: Advanced Science. 7, 23, 19 p., 2002155.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Cell-autonomous astrocytopathy in Alzheimer's disease

    Verkhratsky, A. & Rodriguez, J. J., 2018, In: Acta Physiologica. 223, 2, 3 p., e13070.

    Research output: Contribution to journal › Editorial › Research › peer-review

  23. Published

    Cell-intrinsic glial pathology is conserved across human and murine models of Huntington's disease

    Benraiss, A., Mariani, J. N., Osipovitch, M., Cornwell, A., Windrem, M. S., Villanueva, C. B., Chandler-Militello, D. & Goldman, Steven Alan, 2021, In: Cell Reports. 36, 1, 25 p., 109308.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Cellular Control of Brain Capillary Blood Flow: In Vivo Imaging Veritas

    Grutzendler, J. & Nedergaard, Maiken, 2019, In: Trends in Neurosciences. 42, 8, p. 528-536 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Cerebral Metabolic Changes During Sleep

    Aalling, Nadia, Nedergaard, Maiken & DiNuzzo, M., 1 Sep 2018, In: Current Neurology and Neuroscience Reports. 18, 9, 17 p., 57.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    Cerebral glycogen in humans following acute and recurrent hypoglycemia: Implications on a role in hypoglycemia unawareness

    Öz, G., DiNuzzo, M., Kumar, A., Moheet, A., Khowaja, A., Kubisiak, K., Eberly, L. E. & Seaquist, E. R., 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 8, p. 2883-2893 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Cerebral small vessel disease: A glymphopathy?

    Benveniste, H. & Nedergaard, Maiken, 2021, In: Current Opinion in Neurobiology. 72, p. 15-21 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Cerebrospinal fluid clearance in Alzheimer disease measured with dynamic PET

    De Leon, M. J., Li, Y., Okamura, N., Tsui, W. H., Saint-Louis, L. A., Glodzik, L., Osorio, R. S., Fortea, J., Butler, T., Pirraglia, E., Fossati, S., Kim, H. J., Carare, R. O., Nedergaard, Maiken, Benveniste, H. & Rusinek, H., 2017, In: Journal of Nuclear Medicine. 58, 9, p. 1471-1476 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Cerebrospinal fluid influx drives acute ischemic tissue swelling

    Mestre, H., Du, T., Sweeney, A. M., Liu, G., Samson, A. J., Peng, W., Mortensen, K. N., Stæger, F. F., Bork, P. A. R., Bashford, L., Toro, E. R., Tithof, J., Kelley, D. H., Thomas, J. H., Hjorth, P. G., Martens, E. A., Mehta, R. I., Solis, O., Blinder, P., Kleinfeld, D. & 3 others, Hirase, Hajime, Mori, Yuki & Nedergaard, Maiken, 2020, In: Science. 367, 6483, 8 p., eaaw7462.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Cerebrospinal fluid is a significant fluid source for anoxic cerebral oedema

    Du, T., Mestre, H., Kress, B. T., Liu, G., Sweeney, A. M., Samson, A. J., Rasmussen, M. K., Mortensen, K. N., Bork, P. A. R., Peng, W., Olveda, G. E., Bashford, L., Toro, E. R., Tithof, J., Kelley, D. H., Thomas, J. H., Hjorth, P. G., Martens, E. A., Mehta, R. I., Hirase, H. & 2 others, Mori, Yuki & Nedergaard, Maiken, 2022, In: Brain. 145, 2, p. 787–797 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Changes in the composition of brain interstitial ions control the sleep-wake cycle

    Ding, F., O'Donnell, J., Xu, Q., Kang, N., Goldman, N. & Nedergaard, Maiken, 29 Apr 2016, In: Science. 352, 6285, p. 550-555 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Changes in visual processing during progression of Tau accumulation and neurodegeneration in a mouse model of human tauopathy

    Parka, A., Nedergaard, Maiken, Sotty, F. & Laursen, B., 2021, In: Investigative Ophthalmology & Visual Science. 62, 8, 3 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  33. Published

    Charcot's arthropathy following digital amputation in the diabetic foot

    Bitsch, Mikael, Saunte, Ditte Marie, Dall, C. & Holstein, P. E., 1 Jan 2003, In: Foot and Ankle Surgery. 9, 4, p. 217-220 4 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  34. E-pub ahead of print

    Chronic sleep fragmentation impairs brain interstitial clearance in young wildtype mice

    Deng, Saiyue, Hu, Y., Chen, S., Xue, Yang, Yao, D., Sun, Q., Nedergaard, Maiken, Wang, W. & Ding, Fengfei, 2024, (E-pub ahead of print) In: Journal of Cerebral Blood Flow and Metabolism.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Circadian control of brain glymphatic and lymphatic fluid flow

    Hablitz, L. M., Plá, V., Giannetto, M., Vinitsky, H. S., Stæger, Frederik Filip Vinggaard, Metcalfe, T., Nguyen, R., Benrais, A. & Nedergaard, Maiken, 2020, In: Nature Communications. 11, 1, 4411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Cisterna magna injection in rats to study glymphatic function

    Ramos, M., Burdon Bechet, N., Battistella, R., Pavan, C., L R Xavier, Anna , Nedergaard, Maiken & Lundgaard, I., 2019, Astrocytes: Methods and Protocols. Di Benedetto, B. (ed.). Humana Press, p. 97-104 8 p. (Methods in Molecular Biology, Vol. 1938).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  37. Published

    Cleaning the sleeping brain – the potential restorative function of the glymphatic system

    Hauglund, Natalie Linea, Pavan, C. & Nedergaard, Maiken, 1 Jun 2020, In: Current Opinion in Physiology. 15, 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Comparative analysis of monoaminergic cerebrospinal fluid-contacting cells in Osteichthyes (bony vertebrates)

    L R Xavier, Anna , Fontaine, R., Bloch, S., Affaticati, P., Jenett, A., Demarque, M., Vernier, P. & Yamamoto, K., Jun 2017, In: Journal of Comparative Neurology. 525, 9, p. 2265-2283 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Computational Flux Balance Analysis Predicts that Stimulation of Energy Metabolism in Astrocytes and their Metabolic Interactions with Neurons Depend on Uptake of K(+) Rather than Glutamate

    DiNuzzo, M., Giove, F., Maraviglia, B. & Mangia, S., Jan 2017, In: Neurochemical Research. 42, 1, p. 202-16 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease

    Osorio, M. J., Rowitch, D. H., Tesar, P., Wernig, M., Windrem, M. S. & Goldman, Steven Alan, Feb 2017, In: Stem Cells. 35, 2, p. 311-315 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  41. Published

    Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes

    Li, J., Pan, L., Godoy, M., Pembroke, W. G., Rexach, J. E., Condro, M. C., Alvarado, A. G., Harteni, M., Chen, Y., Stiles, L., Chen, A. Y., Wanner, I. B., Yang, X., Goldman, Steven Alan, Geschwind, D. H., Kornblum, H. & Zhang, Y., 2021, In: Nature Communications. 12, 1, 20 p., 3958.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes

    Li, J., Pan, L., Pembroke, W. G., Rexach, J. E., Godoy, M. I., Condro, M. C., Alvarado, A. G., Harteni, M., Chen, Y., Stiles, L., Chen, A. Y., Wanner, I. B., Yang, X., Goldman, Steven Alan, Geschwind, D. H., Kornblum, H. I. & Zhang, Y., 2021, p. E172-E173. 2 p.

    Research output: Contribution to conference › Poster › Research › peer-review

  43. Published

    Contributions of the Na⁺/K⁺-ATPase, NKCC1, and Kir4.1 to hippocampal K⁺ clearance and volume responses

    Larsen, B. R., Assentoft, M., Cotrina, M. L., Hua, S. Z., Nedergaard, Maiken, Kaila, K., Voipio, J. & MacAulay, Nanna, Apr 2014, In: Glia. 62, 4, p. 608-22 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Cortex-wide Changes in Extracellular Potassium Ions Parallel Brain State Transitions in Awake Behaving Mice

    Rasmussen, R., Nicholas, E., Petersen, Nicolas Caesar, Dietz, Andrea Grostøl, Xu, Q., Sun, Q. & Nedergaard, Maiken, 2019, In: Cell Reports. 28, 5, p. 1182-1194 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Could dexmedetomidine be repurposed as a glymphatic enhancer?

    Persson, N. D. Å., Uusalo, P., Nedergaard, Maiken, Lohela, T. J. & Lilius, T. O., 2022, In: Trends in Pharmacological Sciences. 43, 12, p. 1030-1040 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 “ISMRM Imaging Neurofluids Study group” Workshop in Rome

    Agarwal, N., Lewis, L. D., Hirschler, L., Rivera, L. R., Naganawa, S., Levendovszky, S. R., Ringstad, G., Klarica, M., Wardlaw, J., Iadecola, C., Hawkes, C., Carare, R. O., Wells, J., Bakker, E. N. T. P., Kurtcuoglu, V., Bilston, L., Nedergaard, M., Mori, Y., Stoodley, M., Alperin, N. & 2 others, de Leon, M. & van Osch, M. J. P., 2024, In: Journal of Magnetic Resonance Imaging. 59, 2, 19 p.

    Research output: Contribution to journal › Review › Research › peer-review

  47. Published

    DNase treatment prevents CSF block in early experimental pneumococcal meningitis

    Pavan, C., L R Xavier, Anna , Ramos, M., Fisher, J., Kritsilis, M., Linder, A., Bentzer, P., Nedergaard, Maiken & Lundgaard, I., 2021, In: Annals of Neurology. 90, 4, p. 653-669 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Defining novel functions for cerebrospinal fluid in ALS pathophysiology

    Ng Kee Kwong, K. C., Mehta, A. R., Nedergaard, Maiken & Chandran, S., 2020, In: Acta Neuropathologica Communications. 8, 1, 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice

    Mathiesen, B. K., Miyakoshi, L. M., Cederroth, C. R., Tserga, E., Versteegh, C., Bork, Peter Aleksander Rousing, Hauglund, Natalie Linea, Gomolka, Ryszard Stefan, Mori, Yuki, Edvall, N. K., Rouse, S., Møllgård, Kjeld, Holt, J. R., Nedergaard, Maiken & Canlon, B., 2023, In: Science Translational Medicine. 15, 702, 13 p., eabq3916.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Depth-targeted intracortical microstroke by two-photon photothrombosis in rodent brain

    Fukuda, M., Matsumura, T., Suda, T. & Hirase, Hajime, 2022, In: Neurophotonics. 9, 2, 9 p., 021910.

    Research output: Contribution to journal › Journal article › Research › peer-review

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