Center for Translational Neuromedicine

  1. Published

    Derivation of telencephalic oligodendrocyte progenitors from human pluripotent stem cells

    Major, T., Powers, A. & Tabar, V., Nov 2016, In: Current Protocols in Stem Cell Biology. 39, 1, p. 1H.10.1-1H.10.23 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Design of gadoteridol-loaded cationic liposomal adjuvant CAF01 for MRI of lung deposition of intrapulmonary administered particles

    Thakur, A., Rose, F., Ansari, S. R., Koch, P., Martini, V., Ovesen, S. L., Quistorff, B., Maritim, S., Hyder, F., Andersen, Peter, Christensen, D., Mori, Yuki & Foged, Camilla, 2019, In: Molecular Pharmaceutics. 16, 11, p. 4725-4737 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Determination of intracellular chloride concentration in glial cell types using fluorescence lifetime imaging microscopy (FLIM)

    Engels, M., Untiet, Verena, Gensch, T., Kovermann, P. & Fahlke, C., 2019. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  4. Published

    Development of 11C-labeled CRANAD-102 for positron emission tomography imaging of soluble Aβ-species

    Staudt, Markus, Shalgunov, Vladimir, Nedergaard, Maiken & Herth, Matthias Manfred, 2023, In: Journal of Labelled Compounds and Radiopharmaceuticals. 66, 12, p. 393-399

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Development of the entorhinal cortex occurs via parallel lamination during neurogenesis

    Liu, Y., Bergmann, T., Mori, Yuki, Peralvo Vidal, Juan Miguel, Pihl, M., Vasistha, Navneet A, Thomsen, Preben Dybdahl, Seemann, Ernst Stefan, Gorodkin, Jan, Hyttel, P., Khodosevich, Konstantin, Witter, M. P. & Hall, Vanessa Jane, 2021, In: Frontiers in Neuroanatomy. 15, 19 p., 663667.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Developmental trajectory of episodic-like memory in rats

    Asiminas, Antonios, Lyon, S. A., Langston, R. F. & Wood, E. R., 2022, In: Frontiers in Behavioral Neuroscience. 16, 20 p., 969871.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs

    Lilius, T. O., Blomqvist, K., Hauglund, Natalie Linea, Liu, G., Stæger, Frederik Filip Vinggaard, Baerentzen, S., Du, T., Ahlstrom, F., Backman, J. T., Kalso, E. A., Rauhala, P. V. & Nedergaard, Maiken, 2019, In: Journal of Controlled Release. 304, p. 29-38 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Direct Measurement of Cerebrospinal Fluid Production in Mice

    Liu, G., Mestre, H., Sweeney, A. M., Sun, Q., Weikop, Pia, Du, T. & Nedergaard, Maiken, 2020, In: Cell Reports. 33, 12, 13 p., 108524.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons

    Nolbrant, S., Giacomoni, J., Hoban, D. B., Bruzelius, A., Birtele, M., Chandler-Militello, D., Pereira, M., Ottosson, D. R., Goldman, Steven Alan & Parmar, M., 2020, In: Stem Cell Reports. 15, 4, p. 869-882 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Direct conversion of hESC-derived glial progenitors into midbrain dopaminergic neurons

    Nolbrant, S., Hoban, D., Giacomoni, J., Ottosson, D. R., Goldman, Steven Alan & Parmar, M., 2019, In: Glia. 67, S1, p. E662-E663 2 p., T16-015B.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  11. Published

    Direct neuronal glucose uptake Heralds activity-dependent increases in cerebral metabolism

    Lundgaard, I., Li, B., Xie, L., Kang, H., Sanggaard, S., Haswell, J. D. R., Sun, W., Goldman, S., Blekot, S., Nielsen, Michael Lund, Takano, T., Deane, R. & Nedergaard, Maiken, 2015, In: Nature Communications. 6, 12 p., 6807.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Disruption of Semantic Network in Mild Alzheimer's Disease Revealed by Resting-State fMRI

    Mascali, D., DiNuzzo, M., Serra, L., Mangia, S., Maraviglia, B., Bozzali, M. & Giove, F., 2018, In: Neuroscience. 371, p. 38-48 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance

    Oe, Y., Wang, Xiaowen, Patriarchi, T., Konno, A., Ozawa, K., Yahagi, K., Hirai, H., Tian, L., McHugh, T. J. & Hirase, Hajime, 2020, In: Nature Communications. 11, 1, 15 p., 471.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain?

    Oberheim Bush, N. A. & Nedergaard, Maiken, Sep 2017, In: Neurochemical Research. 42, 9, p. 2577-2587 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Does Global Astrocytic Calcium Signaling Participate in Awake Brain State Transitions and Neuronal Circuit Function?

    Kjærby, Celia, Rasmussen, R., Andersen, Mie & Nedergaard, Maiken, Jun 2017, In: Neurochemical Research. 42, 6, p. 1810-1822 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Does Long-Duration Exposure to Microgravity Lead to Dysregulation of the Brain and Ocular Glymphatic Systems?

    Wostyn, P., Mader, T. H., Gibson, C. R. & Nedergaard, Maiken, 2022, In: Eye and Brain. 14, p. 49-58 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Donor cell memory confers a metastable state of directly converted cells

    Kim, K. P., Li, C., Bunina, D., Jeong, H. W., Ghelman, J., Yoon, J., Shin, B., Park, H., Han, D. W., Zaugg, J. B., Kim, J., Kuhlmann, T., Adams, R. H., Noh, K. M., Goldman, Steven Alan & Schöler, H. R., 2021, In: Cell Stem Cell. 28, 7, p. 1291-1306.e10 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Dorsal striatal dopamine induces fronto-cortical hypoactivity and attenuates anxiety and compulsive behaviors in rats

    Casado-Sainz, A., Gudmundsen, F., Baerentzen, S. L., Lange, D., Ringsted, A., Martinez-Tejada, I., Medina, S., Lee, H., Svarer, C., Keller, S. H., Schain, M., Kjærby, Celia, Fisher, P. M., Cumming, P. & Palner, M., 2022, In: Neuropsychopharmacology. 47, p. 454–464 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Dynamic fluctuations of the locus coeruleus-norepinephrine system underlie sleep state transitions

    Kjærby, Celia, Andersen, Mie, Hauglund, Natalie Linea, Ding, F., Wang, W., Xu, Q., Deng, S., Kang, N., Peng, S., Sun, Q., Dall, C., Jørgensen, P. K., Feng, J., Li, Y., Weikop, Pia, Hirase, Hajime & Nedergaard, Maiken, 2 Sep 2020, 1 p.

    Research output: Other contributionResearch

  20. Published

    Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling

    Liu, Z., Osipovitch, M., Benraiss, A., Huynh, N. P. T., Foti, R., Bates, J., Chandler-Militello, D., Findling, R. L., Tesar, P. J., Nedergaard, Maiken, Windrem, M. S. & Goldman, Steven Alan, 2019, In: Cell Reports. 27, 13, p. 3832-3843, e1-e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    EARLY ADDRESS OF POST-TRAUMATIC GLYMPHATIC INSUFFICIENCY REDUCES NEURONAL/GLIAL CELL DEATH AND TISSUE DAMAGES

    Hussain, R., Wang, W. & Nedergaard, Maiken, 2019, In: Journal of Neurotrauma. 36, 13, p. A-101 1 p., B04-05.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  22. Published

    EARLY INTRODUCTION TO HIGH-INTENSITY INTERVAL TRAINING IN STROKE ASSOCIATES WITH SUSTAINED VIGOROUS-INTENSITY ACTIVITY AT LONG-TERM FOLLOW-UP - RESULTS FROM THE HITPALS STUDY

    Krawcyk, R. S., Vinther, A., Petersen, Nicolas Caesar, Faber, Jens, Iversen, Helle Klingenberg, Christensen, T., Lambertsen, K., Klausen, T., Rostrup, E. & Kruuse, Christina Rostrup, 2020, In: International Journal of Stroke. 15, Supplement 1, p. 132 00477 / #2449.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  23. Published

    Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model

    Parka, A., Degel, C., Dreyer, J., Richter, U., Hall, B., Bastlund, J. F., Laursen, B., Nedergaard, Maiken, Sotty, F. & Botta, P., 2023, In: Neurobiology of Disease. 178, 13 p., 106012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Editorial: Role of Astrocytes in Seizures Induced by Traumatic Brain Injury

    Wang, F., Pan, F., Hirase, Hajime & Huang, J. H., 2020, In: Frontiers in Neurology. 11, 604788.

    Research output: Contribution to journalEditorialResearchpeer-review

  25. Published

    Editorial: Sleep and Mood Disorders

    Verkhratsky, A., Nedergaard, Maiken, Steardo, L. & Li, B., 2020, In: Frontiers in Psychiatry. 10, 3 p., 981.

    Research output: Contribution to journalEditorialResearchpeer-review

  26. Published

    Editorial: Neuroglia Molecular Mechanisms in Psychiatric Disorders

    Scuderi, C., Noda, M. & Verkhratsky, A., 2018, In: Frontiers in Molecular Neuroscience. 11, 2 p., 407.

    Research output: Contribution to journalEditorialResearchpeer-review

  27. Published

    Effect of ADHD medication in male C57BL/6J mice performing the rodent Continuous Performance Test

    Caballero-Puntiverio, M., Lerdrup, L. S., Grupe, M., Larsen, C. W., Dietz, Andrea Grostøl & Andreasen T., Jesper, 2019, In: Psychopharmacology. 236, 6, p. 1839-1851 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty

    Thrane, V. R., Thrane, A. S., Bergo, C., Halvorsen, H. & Krohn, J., 2020, In: Journal of Glaucoma. 29, 4, p. 280-286 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Effect of Home-Based High-Intensity Interval Training in Patients With Lacunar Stroke: A Randomized Controlled Trial

    Krawcyk, R. S., Vinther, A., Petersen, Nicolas Caesar, Faber, Jens, Iversen, Helle Klingenberg, Christensen, T., Lambertsen, K. L., Rehman, S., Klausen, T. W., Rostrup, E. & Kruuse, Christina Rostrup, 2019, In: Frontiers in Neurology. 10, 15 p., 664.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Effect of beta-adrenergic antagonists on the risk of alzheimer's disease amongst hypertensive patients: a nation-wide cohort study

    Beaman, E., Bonde, A. N., Larsen, S. M. U., Ozenne, Brice Maxime Hugues, Lohela, T. J., Gislason, Gunnar Hilmar, Knudsen, Gitte Moos & Holst, S. C., 2020, In: European Neuropsychopharmacology. 40, p. S219-S220 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  31. Published

    Effect of sleep deprivation and NREM sleep stage on physiological brain pulsations

    Helakari, H., Järvelä, M., Väyrynen, T., Tuunanen, J., Piispala, J., Kallio, M., Ebrahimi, S. M., Poltojainen, V., Kananen, J., Elabasy, A., Huotari, N., Raitamaa, L., Tuovinen, T., Korhonen, V., Nedergaard, Maiken & Kiviniemi, V., 2023, In: Frontiers in Neuroscience. 17, 1275184.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Enriched environment enhances β-adrenergic signaling to prevent microglia inflammation by amyloid-β

    Xu, H., Rajsombath, M. M., Weikop, Pia & Selkoe, D. J., 2018, In: EMBO Molecular Medicine. 10, 9, 17 p., e8931.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Erratum: Two types of muscarinic acetylcholine receptors in Drosophila and other arthropods (Cellular and Molecular Life Sciences (2013) 70 (3231-3242) DOI: 10.1007/s0001801313340))

    Collin, C., Hauser, Frank, Gonzalez De Valdivia, E., Li, S., Reisenberger, J., Carlsen, Eva Maria Meier, Khan, Z., Hansen, N. O., Puhm, F., Søndergaard, Leif, Niemiec, J., Heninger, M., Ren, G. R. & Grimmelikhuijzen, Cornelis (Cok), Nov 2013, In: Cellular and Molecular Life Sciences. 70, 21, p. 4197 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  34. Published

    Erythrocytes Are Oxygen-Sensing Regulators of the Cerebral Microcirculation

    Wei, H. S., Kang, H., Rasheed, I. D., Zhou, S., Lou, N., Gershteyn, A., McConnell, E. D., Wang, Y., Richardson, K. E., Palmer, A. F., Xu, C., Wan, J. & Nedergaard, Maiken, 17 Aug 2016, In: Neuron. 91, 4, p. 851-862 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published
  36. Published

    Estimation of protein intestinal digestibility of feeds by means of three-steps technique

    Cabral, L., Valadares, S., Malafaia, P., Lana, R., da Silva, J., Vieira, R. & Pereira, E., 2001, In: Revista Brasileira de Zootecnia. 30, 2, p. 546-552 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Evolution of Neuroglia

    Verkhratsky, A., Ho, M. S. & Parpura, V., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 15-44 30 p. (Advances in Experimental Medicine and Biology, Vol. 1175).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  38. Published

    Experience-dependent changes in hippocampal spatial activity and hippocampal circuit function are disrupted in a rat model of Fragile X Syndrome

    Asiminas, Antonios, Booker, S. A., Dando, O. R., Kozic, Z., Arkell, D., Inkpen, F. H., Sumera, A., Akyel, I., Kind, P. C. & Wood, E. R., 2022, In: Molecular Autism. 13, 1, 29 p., 49.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Feasibility of IVIM parameters from diffusion-weighted imaging at 11.7T MRI for detecting ischemic changes in common carotid artery occlusion rats

    Fujiwara, S., Mori, Yuki, de la Mora, D. M., Akamatsu, Y., Yoshida, K., Shibata, Y., Masuda, T., Ogasawara, K. & Yoshioka, Y., 2020, In: Scientific Reports. 10, 1, 10 p., 8404.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Fibroblast growth factor 21: an endocrine inhibitor of sugar and alcohol appetite

    Holstein-Rønsbo, Stephanie & Gillum, M. P., 2019, In: The Journal of Physiology. 597, 14, p. 3539-3548 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension

    Mestre, H., Tithof, J., Du, T., Song, W., Peng, W., Sweeney, A. M., Olveda, G., Thomas, J. H., Nedergaard, Maiken & Kelley, D. H., 2018, In: Nature Communications. 9, 1, 9 p., 4878.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Fluid Transport in the Brain

    Rasmussen, Martin Kaag, Mestre, H. & Nedergaard, Maiken, 2022, In: Physiological Reviews. 102, p. 1025-1151 27 p.

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    Focal Solute Trapping and Global Glymphatic Pathway Impairment in a Murine Model of Multiple Microinfarcts

    Wang, M., Ding, F., Deng, S., Guo, X., Wang, W., Iliff, J. J. & Nedergaard, Maiken, 15 Mar 2017, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 37, 11, p. 2870-2877 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    General Pathophysiology of Astroglia

    Verkhratsky, A., Ho, M. S., Vardjan, N., Zorec, R. & Parpura, V., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 149-179 31 p. (Advances in Experimental Medicine and Biology, Vol. 1175).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  45. Published

    Genetic haplotype of the glymphatic-associated water channel aquaporin 4 modulates slow waves in human non-rapid eye movement sleep

    Larsen, S. M. U., Landolt, H. P., Berger, W., Nedergaard, Maiken, Knudsen, Gitte Moos & Holst, S. C., 2019, In: European Neuropsychopharmacology. 29, Supplement 6, p. S563-S564 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  46. Published

    Glia Disease and Repair-Remyelination

    Franklin, R. J. M. & Goldman, Steven Alan, Jul 2015, In: Cold Spring Harbor perspectives in biology. 7, 7, p. 1-28 28 p., a020594.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Glia in Health and Disease

    Ho, M. S., Verkhratsky, A., Duan, S. & Parpura, V., 2019, In: Frontiers in Molecular Neuroscience. 12, 3 p., 63.

    Research output: Contribution to journalEditorialResearchpeer-review

  48. Published

    Glial cells in schizophrenia: a unified hypothesis

    Dietz, Andrea Grostøl, Goldman, Steven Alan & Nedergaard, Maiken, 2020, In: Lancet Psychiatry. 7, 3, p. 272-281 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    Glial evolution as a determinant of human behavior and its disorders

    Goldman, Steven Alan, 2020, In: Annals of the New York Academy of Sciences. 1471, 1, p. 72-85 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published

    Glial progenitor cell-based repair of the dysmyelinated brain: Progression to the clinic

    Goldman, Steven Alan, Mariani, J. N. & Madsen, P. M., 2021, In: Seminars in Cell and Developmental Biology. 116, p. 62-70 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  51. Published

    Glial progenitor cell-based treatment of the childhood leukodystrophies

    Osório, M. J. & Goldman, Steven Alan, Sep 2016, In: Experimental Neurology. 283, Part B, p. 476-488 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  52. Published

    Glial progenitor cells of the adult human white and grey matter are contextually distinct

    Osorio, M. J., Mariani, J. N., Zou, L., Schanz, S. J., Heffernan, K., Cornwell, A. & Goldman, Steven Alan, 2023, In: Glia. 71, 3, p. 524-540 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Gliocrine System: Astroglia as Secretory Cells of the CNS

    Vardjan, N., Parpura, V., Verkhratsky, A. & Zorec, R., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 93-115 23 p. (Advances in Experimental Medicine and Biology, Vol. 1175).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  54. Published

    Glycogen distribution in mouse hippocampus

    Hirase, Hajime, Akther, S., Wang, X. & Oe, Y., 2019, In: Journal of Neuroscience Research. 97, 8, p. 923-932 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus

    Reeves, B. C., Karimy, J. K., Kundishora, A. J., Mestre, H., Cerci, H. M., Matouk, C., Alper, S. L., Lundgaard, I., Nedergaard, Maiken & Kahle, K. T., 2020, In: Trends in Molecular Medicine. 26, 3, p. 285-295 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  56. Published

    Glymphatic clearance controls state-dependent changes in brain lactate concentration

    Lundgaard, I., Lu, M. L., Yang, E., Peng, W., Mestre, H., Hitomi, E., Deane, R. & Nedergaard, Maiken, Jun 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 6, p. 2112-2124 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Glymphatic failure as a final common pathway to dementia

    Nedergaard, Maiken & Goldman, Steven Alan, 2020, In: Science (New York, N.Y.). 370, 6512, p. 50-56 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  58. Published

    Glymphatic fluid transport is suppressed by the aquaporin-4 inhibitor AER-271

    Giannetto, M. J., Gomolka, Ryszard Stefan, Gahn-Martinez, D., Newbold, E. J., Bork, Peter Aleksander Rousing, Chang, E., Gresser, M., Thompson, T., Mori, Yuki & Nedergaard, Maiken, 2024, In: Glia. 72, 5, p. 982-998 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Glymphatic influx and clearance are accelerated by neurovascular coupling: [Inkl. Correction]

    Holstein-Rønsbo, Stephanie, Gan, Y., Giannetto, M. J., Rasmussen, Martin Kaag, Sigurdsson, B., Beinlich, Felix Ralf Michael, Rose, Laura, Untiet, Verena, Hablitz, L. M., Kelley, D. H. & Nedergaard, Maiken, 2023, In: Nature Neuroscience. 26, p. 1042–1053

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Glymphatic system

    Benveniste, H. & Nedergaard, Maiken, 2016, Neuroscience in the 21st Century: From Basic to Clinical. 2 ed. Springer, p. 1945-1962 18 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  61. Published

    Glymphatic system and Spaceflight Associated Neuro-Ocular Syndrome

    Wostyn, P. & Nedergaard, Maiken, 2022, Spaceflight Associated Neuro-Ocular Syndrome. Elsevier, p. 67-76 10 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  62. Published

    Glymphatic system dysfunction in neurodegenerative diseases

    Beschorner, Natalie & Nedergaard, Maiken, 2024, In: Current Opinion in Neurology. 37, 2, p. 182-188 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  63. Published

    Glymphatic-assisted perivascular brain delivery of intrathecal small gold nanoparticles

    Lilius, T. O., Mortensen, K. N., Deville, C., Lohela, T. J., Stæger, Frederik Filip Vinggaard, Sigurdsson, B., Fiordaliso, E. M., Rosenholm, Marko, Kamphuis, C., Beekman, F. J., Jensen, A. I. & Nedergaard, Maiken, 2023, In: Journal of Controlled Release. 355, p. 135-148 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Grid-climbing Behaviour as a Pain Measure for Cancer-induced Bone Pain and Neuropathic Pain

    Falk, S., Gallego-Pedersen, S. & Petersen, Nicolas Caesar, Jul 2017, In: In Vivo. 31, 4, p. 619-623

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Haplotype of the astrocytic water channel AQP4 is associated with slow wave energy regulation in human NREM sleep

    Larsen, S. M. U., Landolt, H. P., Berger, W., Nedergaard, Maiken, Knudsen, Gitte Moos & Holst, S. C., May 2020, In: PLOS Biology. 18, 5, 14 p., e3000623.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Home-based aerobic exercise in patients with lacunar stroke: Design of the HITPALS randomized controlled trial

    Krawcyk, R. S., Vinther, A., Petersen, Nicolas Caesar, Faber, Jens, Hansen, R. H., Rostrup, E. & Kruuse, Christina Rostrup, 2019, In: Contemporary Clinical Trials Communications. 14, 9 p., 100332.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. E-pub ahead of print

    How astrocytic chloride modulates brain states

    Untiet, Verena & Verkhratsky, A., 2024, (E-pub ahead of print) In: BioEssays.

    Research output: Contribution to journalReviewResearchpeer-review

  68. Published

    How to make an oligodendrocyte

    Goldman, Steven Alan & Kuypers, N. J., 1 Dec 2015, In: Development. 142, 23, p. 3983-3995 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Human ESC-Derived Chimeric Mouse Models of Huntington's Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation

    Osipovitch, M., Martinez, A. A., Mariani, J. N., Cornwell, A., Dhaliwal, S., Zou, L., Chandler-Militello, D., Wang, S., Li, X., Benraiss, S., Agate, R., Lampp, A., Benraiss, A., Windrem, M. S. & Goldman, Steven Alan, 2019, In: Cell Stem Cell. 24, 1, p. 107-122.e7

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Human Glial Chimeric Mice to Define the Role of Glial Pathology in Human Disease

    Mariani, J. N., Zou, L. & Goldman, Steven Alan, 2019, Oligodendrocytes. Springer, Vol. 1936. p. 311-331 21 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  71. Published

    Human Glial Progenitor Cells Effectively Remyelinate the Demyelinated Adult Brain

    Windrem, M. S., Schanz, S. J., Zou, L., Chandler-Militello, D., Kuypers, N. J., Nedergaard, Maiken, Lu, Y., Mariani, J. N. & Goldman, Steven Alan, 2020, In: Cell Reports. 31, 7, 23 p., 107658.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Human NREM Sleep Promotes Brain-Wide Vasomotor and Respiratory Pulsations

    Helakari, H., Korhonen, V., Holst, S. C., Piispala, J., Kallio, M., Väyrynen, T., Huotari, N., Raitamaa, L., Tuunanen, J., Kananen, J., Järvelä, M., Tuovinen, T., Raatikainen, V., Borchardt, V., Kinnunen, H., Nedergaard, Maiken & Kiviniemi, V., 2022, In: Journal of Neuroscience. 42, 12, p. 2503-2515 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. E-pub ahead of print

    Human brain clearance imaging: Pathways taken by magnetic resonance imaging contrast agents after administration in cerebrospinal fluid and blood

    van Osch, M. J. P., Wåhlin, A., Scheyhing, P., Mossige, I., Hirschler, L., Eklund, A., Mogensen, K., Gomolka, Ryszard Stefan, Radbruch, A., Qvarlander, S., Decker, A., Nedergaard, Maiken, Mori, Yuki, Eide, P. K., Deike, K. & Ringstad, G., 2024, (E-pub ahead of print) In: NMR in Biomedicine.

    Research output: Contribution to journalReviewResearchpeer-review

  74. Published

    Human glia can both induce and rescue aspects of disease phenotype in Huntington disease

    Benraiss, A., Wang, S., Herrlinger, S., Li, X., Chandler-Militello, D., Mauceri, J., Burm, H. B., Toner, M., Osipovitch, M., Jim Xu, Q., Ding, F., Wang, F., Kang, N., Kang, J., Curtin, P. C., Brunner, D., Windrem, M. S., Munoz-Sanjuan, I., Nedergaard, Maiken & Goldman, Steven Alan, 7 Jun 2016, In: Nature Communications. 7, 13 p., 11758.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Human glial chimeric mice reveal astrocytic dependence of JC virus infection

    Kondo, Y., Windrem, M. S., Zou, L., Chandler-Militello, D., Schanz, S. J., Auvergne, R. M., Betstadt, S. J., Harrington, A. R., Johnson, M., Kazarov, A., Gorelik, L. & Goldman, Steven Alan, 1 Dec 2014, In: The Journal of Clinical Investigation. 124, 12, p. 5323-36 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia

    Windrem, M. S., Osipovitch, M., Liu, Z., Bates, J., Chandler-Militello, D., Zou, L., Munir, J., Schanz, S., McCoy, K., Miller, R. H., Wang, S., Nedergaard, Maiken, Findling, R. L., Tesar, P. J. & Goldman, Steven Alan, 3 Aug 2017, In: Cell Stem Cell. 21, 2, p. 195-208.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Human iPSC-derived neural precursor cells differentiate into multiple cell types to delay disease progression following transplantation into YAC128 Huntington's disease mouse model

    Park, H. J., Jeon, J., Choi, J., Kim, J. Y., Kim, H. S., Huh, J. Y., Goldman, Steven Alan & Song, J., 2021, In: Cell Proliferation. 54, 8, 16 p., e13082.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Human integrin α10β1-selected mesenchymal stem cells home to cartilage defects in the rabbit knee and assume a chondrocyte-like phenotype

    Andersen, Camilla, Uvebrant, K., Mori, Yuki, Aarsvold, S., Jacobsen, Stine, Berg, Lise Charlotte, Lundgren-åkerlund, E. & Lindegaard, Casper, 2022, In: Stem Cell Research & Therapy. 13, 15 p., 206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update

    Lovell-Badge, R., Anthony, E., Barker, R. A., Bubela, T., Brivanlou, A. H., Carpenter, M., Charo, R. A., Clark, A., Clayton, E., Cong, Y., Daley, G. Q., Fu, J., Fujita, M., Greenfield, A., Goldman, S. A., Hill, L., Hyun, I., Isasi, R., Kahn, J., Kato, K. & 27 others, Kim, J. S., Kimmelman, J., Knoblich, J. A., Mathews, D., Montserrat, N., Mosher, J., Munsie, M., Nakauchi, H., Naldini, L., Naughton, G., Niakan, K., Ogbogu, U., Pedersen, R., Rivron, N., Rooke, H., Rossant, J., Round, J., Saitou, M., Sipp, D., Steffann, J., Sugarman, J., Surani, A., Takahashi, J., Tang, F., Turner, L., Zettler, P. J. & Zhai, X., 2021, In: Stem Cell Reports. 16, 6, p. 1398-1408 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  80. Published

    ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts

    Hyun, I., Clayton, E. W., Cong, Y., Fujita, M., Goldman, Steven Alan, Hill, L. R., Monserrat, N., Nakauchi, H., Pedersen, R. A., Rooke, H. M., Takahashi, J. & Knoblich, J. A., 2021, In: Stem Cell Reports. 16, 6, p. 1409-1415 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  81. Published

    Impact of Global Mean Normalization on Regional Glucose Metabolism in the Human Brain

    Mortensen, K. N., Gjedde, Albert, Thompson, G. J., Herman, P., Parent, M. J., Rothman, D. L., Kupers, Ron, Ptito, Maurice, Stender, J., Laureys, S., Riedl, V., Alkire, M. T. & Hyder, F., 2018, In: Neural Plasticity. 2018, 16 p., 6120925.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Impaired GABAergic Inhibition in the Prefrontal Cortex of Early Postnatal Phencyclidine (PCP)-Treated Rats

    Kjærby, Celia, Broberg, B. V., Kristiansen, Uffe & Dalby, N. O., 2014, In: Cerebral Cortex. 24, 9, p. 2522-32 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Impaired Glymphatic Transport in Spontaneously Hypertensive Rats

    Nygaard Mortensen, K., Sanggaard, S., Mestre, H., Lee, H., Kostrikov, S., L R Xavier, Anna , Gjedde, Albert, Benveniste, H. & Nedergaard, Maiken, 2019, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 32, p. 6365-6377 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Impairment of the glymphatic system after diabetes

    Jiang, Q., Zhang, L., Ding, G., Davoodi-Bojd, E., Li, Q., Li, L., Sadry, N., Nedergaard, Maiken, Chopp, M. & Zhang, Z., 1 Apr 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 4, p. 1326-1337 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Implications of the discovery of brain lymphatic pathways

    Iliff, J. J., Goldman, Steven Alan & Nedergaard, Maiken, 2015, In: Lancet Neurology. 14, 10, p. 977-979 3 p.

    Research output: Contribution to journalJournal articleCommunication

  86. Published

    In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy

    Sweeney, A. M., Pla, V., Du, T., Liu, G., Sun, Q., Peng, S., Plog, B. A., Kress, B. T., Wang, X., Mestre, H. & Nedergaard, Maiken, 2019, In: Journal of Visualized Experiments. 149, 7 p., e59774.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Increased activity of glial glutamate transporter-associated anion channels results in episodic ataxia 6

    Kovermann, P., Untiet, Verena, Kolobkova, Y. & Fahlke, C., 2019, In: Glia. 67, S1, p. E216 1 p., T05-034A.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  88. Published

    Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia

    Hablitz, L. M., Vinitsky, H. S., Sun, Q., Stæger, Frederik Filip Vinggaard, Sigurdsson, B., Mortensen, K. N., Lilius, T. O. & Nedergaard, Maiken, 2019, In: Science Advances. 5, 2, 9 p., eaav5447.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Increased interictal synchronicity of respiratory related brain pulsations in epilepsy

    Kananen, J., Järvelä, M., Korhonen, V., Tuovinen, T., Huotari, N., Raitamaa, L., Helakari, H., Väyrynen, T., Raatikainen, V., Nedergaard, Maiken, Ansakorpi, H., Jacobs, J., LeVan, P. & Kiviniemi, V., 2022, In: Journal of Cerebral Blood Flow and Metabolism. 42, 10, p. 1840-1853 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets

    Karimy, J. K., Reeves, B. C., Damisah, E., Duy, P. Q., Antwi, P., David, W., Wang, K., Schiff, S. J., Limbrick, D. D. ,. J., Alper, S. L., Warf, B. C., Nedergaard, Maiken, Simard, J. M. & Kahle, K. T., 2020, In: Nature Reviews Neurology. 16, p. 285–296 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  91. Published

    Insulin-like growth factor 1 supplementation supports motor coordination and affects myelination in preterm pigs

    Christiansen, Line Iadsatian, Ventura, G. C., Holmqvist, B., Aasmul-Olsen, Karoline, Lindholm, S. E. H., Lycas, M. D., Mori, Yuki, Secher, Jan Bojsen-Møller, Burrin, D. G., Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2023, In: Frontiers in Neuroscience. 17, 15 p., 1205819.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Interstitial ions: A key regulator of state-dependent neural activity?

    Rasmussen, R., O'Donnell, J., Ding, F. & Nedergaard, Maiken, 2020, In: Progress in Neurobiology. 98, 101802.

    Research output: Contribution to journalReviewResearchpeer-review

  93. Published

    Introducing the special issue on “Proteins and Circuits in Memory”

    Kjærgaard, M., Petersen, Nicolas Caesar, Sørensen, Jakob Balslev & Takeuchi, T., 2021, In: European Journal of Neuroscience. 54, 8, p. 6691-6695 5 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  94. Published

    Inverse correlation of fluctuations of cerebral blood and water concentrations in humans

    Borchardt, V., Korhonen, V., Helakari, H., Nedergaard, Maiken, Myllylä, T. & Kiviniemi, V., 2021, In: European Physical Journal Plus. 136, 5, 497.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Ionic signalling in astroglia beyond calcium

    Verkhratsky, A., Untiet, Verena & Rose, C. R., 2020, In: The Journal of Physiology. 598, 9, p. 1655-1670 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  96. Published

    Ketamine reduces electrophysiological network activity in cortical neuron cultures already at sub-micromolar concentrations – Impact on TrkB-ERK1/2 signaling

    Ahtiainen, A., Annala, I., Rosenholm, Marko, Kohtala, S., Hyttinen, J., Tanskanen, J. M. A. & Rantamäki, T., 2023, In: Neuropharmacology. 229, 11 p., 109481.

    Research output: Contribution to journalReviewResearchpeer-review

  97. Published

    Lactate biosensors for spectrally and spatially multiplexed fluorescence imaging

    Nasu, Y., Aggarwal, A., Le, G. N. T., Vo, C. T., Kambe, Y., Wang, X., Beinlich, F. R. M., Lee, A. B., Ram, T. R., Wang, F., Gorzo, K. A., Kamijo, Y., Boisvert, M., Nishinami, S., Kawamura, G., Ozawa, T., Toda, H., Gordon, G. R., Ge, S., Hirase, H. & 5 others, Nedergaard, Maiken, Paquet, M. E., Drobizhev, M., Podgorski, K. & Campbell, R. E., 2023, In: Nature Communications. 14, 1, 17 p., 6598.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Liver-secreted fluorescent blood plasma markers enable chronic imaging of the microcirculation

    Wang, Xiaowen, Delle, Christine, Asiminas, Antonios, Akther, S., Vittani, Marta, Brøgger, Peter, Kusk, P., Vo, C. T., Radovanovic, Tessa, Konno, A., Hirai, H., Fukuda, M., Weikop, Pia, Goldman, Steven Alan, Nedergaard, Maiken & Hirase, Hajime, 2022, In: Cell Reports Methods. 2, 10, 16 p., 100302.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Local extracellular K+ in cortex regulates norepinephrine levels, network state, and behavioral output

    Dietz, Andrea Grostøl, Weikop, Pia, Hauglund, Natalie Linea, Andersen, Mie, Petersen, Nicolas Caesar, Rose, Laura, Hirase, Hajime & Nedergaard, Maiken, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 40, 9 p., e2305071120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Locomotion Induces Fundamentally Different Patterns of Ca2+Signaling in Astrocytes and Neurons

    Hirase, Hajime & Nedergaard, Maiken, 2023, In: Function. 4, 4, 2 p., zqad028.

    Research output: Contribution to journalComment/debateResearchpeer-review