Center for Translational Neuromedicine

  1. 2017
  2. Published

    Perivascular spaces, glymphatic dysfunction, and small vessel disease

    Mestre, H., Kostrikov, S., Mehta, R. I. & Nedergaard, Maiken, 1 Sep 2017, In: Clinical Science. 131, 17, p. 2257-2274 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Understanding the functions and relationships of the glymphatic system and meningeal lymphatics

    Louveau, A., Plog, B. A., Antila, S., Alitalo, K., Nedergaard, Maiken & Kipnis, J., 1 Sep 2017, In: The Journal of Clinical Investigation. 127, 9, p. 3210-3219 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Astrocytes: Tailored to Support the Demand of Neural Circuits?

    Rasmussen, R. & Samson, A. J., 27 Sep 2017, In: Cell Systems. 5, 3, p. 165-167 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Brain energetics during the sleep-wake cycle

    DiNuzzo, M. & Nedergaard, Maiken, Dec 2017, In: Current Opinion in Neurobiology. 47, p. 65-72 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  6. 2018
  7. Published

    AMELIORATION OF GLYMPHATIC PATHWAY IS CRITICAL FOR LONG TERM RECOVERY FROM TRAUMATIC BRAIN INJURY

    Hussain, R., Wang, W., Cheetham-West, A. O., Sun, Q. & Nedergaard, Maiken, 2018, p. A204. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  8. Published

    Altered physiological brain variation in drug-resistant epilepsy

    Kananen, J., Tuovinen, T., Ansakorpi, H., Rytky, S., Helakari, H., Huotari, N., Raitamaa, L., Raatikainen, V., Rasila, A., Borchardt, V., Korhonen, V., LeVan, P., Nedergaard, Maiken & Kiviniemi, V., 2018, In: Brain and Behavior. 8, 9, p. 1-17 17 p., e01090.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Aquaporin-4-dependent glymphatic solute transport in the rodent brain

    Mestre, H., Hablitz, L. M., Xavier, A. L. R., Feng, W., Zou, W., Pu, T., Monai, H., Murlidharan, G., Rivera, R. M. C., Simon, M. J., Pike, M. M., Pla, V., Du, T., Kress, B. T., Wang, X., Plog, B. A., Thrane, A. S., Lundgaard, I., Abe, Y., Yasui, M. & 6 others, Thomas, J. H., Xiao, M., Hirase, Hajime, Asokan, A., Iliff, J. J. & Nedergaard, Maiken, 2018, In: eLife. 7, 31 p., :e40070.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function

    Lundgaard, I., Wang, W., Eberhardt, A., Vinitsky, H. S., Reeves, B. C., Peng, S., Lou, N., Hussain, R. & Nedergaard, Maiken, 2018, In: Scientific Reports. 8, 1, 16 p., 2246.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Brain Segmentation in Rodent MR-Images Using Convolutional Neural Networks

    Sigurdsson, B., Darkner, Sune, Sommer, Stefan Horst, Mortensen, K. N., Sanggaard, S., Kostrikov, S. & Nedergaard, Maiken, 2018.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  12. Published

    Cannula Implantation into the Cisterna Magna of Rodents

    L R Xavier, Anna , Hauglund, Natalie Linea, Holstein-Rønsbo, Stephanie, Li, Q., Sanggaard, S., Lou, N., Lundgaard, I. & Nedergaard, Maiken, 2018, In: Journal of Visualized Experiments. 135, 6 p., e57378.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Cell-autonomous astrocytopathy in Alzheimer's disease

    Verkhratsky, A. & Rodriguez, J. J., 2018, In: Acta Physiologica. 223, 2, 3 p., e13070.

    Research output: Contribution to journalEditorialResearchpeer-review

  14. Published

    Disruption of Semantic Network in Mild Alzheimer's Disease Revealed by Resting-State fMRI

    Mascali, D., DiNuzzo, M., Serra, L., Mangia, S., Maraviglia, B., Bozzali, M. & Giove, F., 2018, In: Neuroscience. 371, p. 38-48 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Editorial: Neuroglia Molecular Mechanisms in Psychiatric Disorders

    Scuderi, C., Noda, M. & Verkhratsky, A., 2018, In: Frontiers in Molecular Neuroscience. 11, 2 p., 407.

    Research output: Contribution to journalEditorialResearchpeer-review

  16. Published

    Enriched environment enhances β-adrenergic signaling to prevent microglia inflammation by amyloid-β

    Xu, H., Rajsombath, M. M., Weikop, Pia & Selkoe, D. J., 2018, In: EMBO Molecular Medicine. 10, 9, 17 p., e8931.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension

    Mestre, H., Tithof, J., Du, T., Song, W., Peng, W., Sweeney, A. M., Olveda, G., Thomas, J. H., Nedergaard, Maiken & Kelley, D. H., 2018, In: Nature Communications. 9, 1, 9 p., 4878.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Impact of Global Mean Normalization on Regional Glucose Metabolism in the Human Brain

    Mortensen, K. N., Gjedde, Albert, Thompson, G. J., Herman, P., Parent, M. J., Rothman, D. L., Kupers, Ron, Ptito, Maurice, Stender, J., Laureys, S., Riedl, V., Alkire, M. T. & Hyder, F., 2018, In: Neural Plasticity. 2018, 16 p., 6120925.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Loss of calretinin and parvalbumin positive interneurones in the hippocampal CA1 of aged Alzheimer's disease mice

    Zallo, F., Gardenal, E., Verkhratsky, A. & Rodríguez, J. J., 2018, In: Neuroscience Letters. 681, p. 19-25 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Neurogenetics of Pelizaeus-Merzbacher disease

    Albuquerque Osório, M. J. & Goldman, Steven Alan, 2018, Neurogenetics of Pelizaeus-Merzbacher disease. Geschwind, D. H., Paulson, H. L. & Klein, C. (eds.). Vol. 148. p. 701-722 22 p. (Handbook of Clinical Neurology, Vol. 148).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  21. Published

    Neuroglia in the autistic brain: evidence from a preclinical model

    Bronzuoli, M. R., Facchinetti, R., Ingrassia, D., Sarvadio, M., Schiavi, S., Steardo, L., Verkhratsky, A., Trezza, V. & Scuderi, C., 2018, In: Molecular Autism. 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Physiology of astroglia

    Verkhratsky, A. & Nedergaard, Maiken, 2018, In: Physiological Reviews. 98, 1, p. 239-389 151 p.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Quantitative Gd-DOTA uptake from cerebrospinal fluid into rat brain using 3D VFA-SPGR at 9.4T

    Lee, H., Mortensen, K., Sanggaard, S., Koch, P., Brunner, H., Quistorff, B., Nedergaard, Maiken & Benveniste, H., 2018, In: Magnetic Resonance in Medicine. 79, 3, p. 1568-1578 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Scale-invariant rearrangement of resting state networks in the human brain under sustained stimulation

    Tommasin, S., Mascali, D., Moraschi, M., Gili, T., Hassan, I. E., Fratini, M., DiNuzzo, M., Wise, R. G., Mangia, S., Macaluso, E. & Giove, F., 2018, In: NeuroImage. 179, p. 570-581 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The developmental neurogenic niche of the Entorhinal cortex revealed by single-cell transcriptomics.

    Bergmann, T. B., Liu, Y., Lee, J., Peralvo Vidal, Juan Miguel, Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Gorodkin, Jan, Hall, Vanessa Jane & Pers, Tune H, 2018.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  26. Published

    The glymphatic pathway in neurological disorders

    Rasmussen, Martin Kaag, Mestre, H. & Nedergaard, Maiken, 2018, In: The Lancet Neurology. 17, 11, p. 1016-1024 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    Transplanted neural progenitors bridge gaps to benefit cord-injured monkeys

    Goldman, Steven Alan, 2018, In: Nature Medicine. 24, 4, p. 388-390 3 p.

    Research output: Contribution to journalJournal articleCommunication

  28. Published

    Uncovering the anatomical and molecular landscape of the developing entorhinal cortex.

    Liu, Y., Bergmann, T. B., Peralvo Vidal, Juan Miguel, Lee, J., Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Gorodkin, Jan, Hyttel, P., Pers, Tune H, witter, M. & Hall, Vanessa Jane, 2018.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  29. Published

    Understanding the role of the perivascular space in cerebral small vessel disease

    Brown, R., Benveniste, H., Black, S. E., Charpak, S., Dichgans, M., Joutel, A., Nedergaard, Maiken, Smith, K. J., Zlokovic, B. V. & Wardlaw, J. M., 2018, In: Cardiovascular Research. 114, 11, p. 1462-1473 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Voluntary running enhances glymphatic influx in awake behaving, young mice

    Holstein-Rønsbo, Stephanie, Petersen, Nicolas Caesar & Nedergaard, Maiken, 2018, In: Neuroscience Letters. 662, p. 253-258 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published
  32. Published

    Branch retinal artery occlusion as a clinical manifestation of hereditary haemorrhagic telangiectasia (Osler-Weber-Rendu syndrome) in pregnancy

    Askim, A. J., Thrane, A. S., Giaever, P., Andersen, R. & Krohn, J., Mar 2018, In: Acta Ophthalmologica. 96, 2, p. 197-199 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The Challenges of First-in-Human Stem Cell Clinical Trials: What Does This Mean for Ethics and Institutional Review Boards?

    Barker, R. A., Carpenter, M. K., Forbes, S., Goldman, Steven Alan, Jamieson, C., Murry, C. E., Takahashi, J. & Weir, G., 8 May 2018, In: Stem Cell Reports. 10, 5, p. 1429-1431 3 p.

    Research output: Contribution to journalComment/debateCommunication

  34. Published

    Cerebral Metabolic Changes During Sleep

    Aalling, Nadia, Nedergaard, Maiken & DiNuzzo, M., 1 Sep 2018, In: Current Neurology and Neuroscience Reports. 18, 9, 17 p., 57.

    Research output: Contribution to journalReviewResearchpeer-review

  35. 2019
  36. Published

    A Survey of Molecular Imaging of Opioid Receptors

    Cumming, P., Marton, J., Lilius, T. O., Olberg, D. E. & Rominger, A., 2019, In: Molecules. 24, 22, 35 p., 4190.

    Research output: Contribution to journalReviewResearchpeer-review

  37. Published

    Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke

    Monai, H., Wang, X., Yahagi, K., Lou, N., Mestre, H., Xu, Q., Abe, Y., Yasui, M., Iwai, Y., Nedergaard, Maiken & Hirase, Hajime, 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 22, p. 11010-11019 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Astrocyte Specific Remodeling of Plasmalemmal Cholesterol Composition by Ketamine Indicates a New Mechanism of Antidepressant Action

    Lasic, E., Lisjak, M., Horvat, A., Bozic, M., Sakanovic, A., Anderluh, G., Verkhratsky, A., Vardjan, N., Jorgacevski, J., Stenovec, M. & Zorec, R., 2019, In: Scientific Reports. 9, 12 p., 10957.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Astrocytes in chronic pain and itch

    Ji, R., Donnelly, C. R. & Nedergaard, Maiken, 2019, In: Nature Reviews Neuroscience. 20, 11, p. 667-685

    Research output: Contribution to journalReviewResearchpeer-review

  40. Published

    Astrocytic connexin 43 potentiates myelin injury in ischemic white matter disease

    Wang, M., Qin, C., Luo, X., Wang, J., Wang, X., Xie, M., Hu, J., Cao, J., Hu, T., Goldman, Steven Alan, Nedergaard, Maiken & Wang, W., 2019, In: Theranostics. 9, 15, p. 4474-4493 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Astroglia in Alzheimer’s Disease

    Verkhratsky, A., Parpura, V., Rodriguez-Arellano, J. J. & Zorec, R., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 273-324 52 p. (Advances in Experimental Medicine and Biology, Vol. 1175).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  42. Published

    Astroglial Calcium Signaling in Aging and Alzheimer's Disease

    Verkhratsky, A., 2019, In: Cold Spring Harbor perspectives in biology. 11, 7, 16 p., a035188 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Astroglial signalling in health and disease

    Verkhratsky, A. & Zorec, R., 2019, In: Neuroscience Letters. 689, p. 1-4 4 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  44. Published

    Astrogliopathology in the infectious insults of the brain

    Zorec, R., Županc, T. A. & Verkhratsky, A., 2019, In: Neuroscience Letters. 689, p. 56-62 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    Brain Morphometry and Longitudinal Relaxation Time of Spontaneously Hypertensive Rats (SHRs) in Early and Intermediate Stages of Hypertension Investigated by 3D VFA-SPGR MRI

    Koundal, S., Liu, X., Sanggaard, S., Mortensen, K., Wardlaw, J., Nedergaard, Maiken, Benveniste, H. & Lee, H., 2019, In: Neuroscience. 404, p. 14-26

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    CHARACTERIZATION OF A RAT MODEL OF ACUTE BACTERIAL MENINGITIS

    Fisher, J., Pavan, C., Linder, A. & Bentzer, P., 2019, In: Shock. 51, Supplement 1 6S, p. 82 1 p., P89.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  47. Published

    Cellular Control of Brain Capillary Blood Flow: In Vivo Imaging Veritas

    Grutzendler, J. & Nedergaard, Maiken, 2019, In: Trends in Neurosciences. 42, 8, p. 528-536 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Cisterna magna injection in rats to study glymphatic function

    Ramos, M., Burdon Bechet, N., Battistella, R., Pavan, C., L R Xavier, Anna , Nedergaard, Maiken & Lundgaard, I., 2019, Astrocytes: Methods and Protocols. Di Benedetto, B. (ed.). Humana Press, p. 97-104 8 p. (Methods in Molecular Biology, Vol. 1938).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  49. Published

    Cortex-wide Changes in Extracellular Potassium Ions Parallel Brain State Transitions in Awake Behaving Mice

    Rasmussen, R., Nicholas, E., Petersen, Nicolas Caesar, Dietz, Andrea Grostøl, Xu, Q., Sun, Q. & Nedergaard, Maiken, 2019, In: Cell Reports. 28, 5, p. 1182-1194 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Design of gadoteridol-loaded cationic liposomal adjuvant CAF01 for MRI of lung deposition of intrapulmonary administered particles

    Thakur, A., Rose, F., Ansari, S. R., Koch, P., Martini, V., Ovesen, S. L., Quistorff, B., Maritim, S., Hyder, F., Andersen, Peter, Christensen, D., Mori, Yuki & Foged, Camilla, 2019, In: Molecular Pharmaceutics. 16, 11, p. 4725-4737 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Determination of intracellular chloride concentration in glial cell types using fluorescence lifetime imaging microscopy (FLIM)

    Engels, M., Untiet, Verena, Gensch, T., Kovermann, P. & Fahlke, C., 2019. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  52. Published

    Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs

    Lilius, T. O., Blomqvist, K., Hauglund, Natalie Linea, Liu, G., Stæger, Frederik Filip Vinggaard, Baerentzen, S., Du, T., Ahlstrom, F., Backman, J. T., Kalso, E. A., Rauhala, P. V. & Nedergaard, Maiken, 2019, In: Journal of Controlled Release. 304, p. 29-38 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Direct conversion of hESC-derived glial progenitors into midbrain dopaminergic neurons

    Nolbrant, S., Hoban, D., Giacomoni, J., Ottosson, D. R., Goldman, Steven Alan & Parmar, M., 2019, In: Glia. 67, S1, p. E662-E663 2 p., T16-015B.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review