Center for Translational Neuromedicine

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  1. Published

    CSF space volumetry using 3D-CISS in Aqp4-deficient mice – quantitative analysis and technical advances

    Gomolka, Ryszard Stefan, Nedergaard, Maiken & Mori, Yuki, 2021, Book of Abstracts ESMRMB 2021 Online 38th Annual Scientific Meeting 7-9 October 2021. Springer, Vol. 34. p. S95-6 2 p. (Magnetic Resonance Materials in Physics, Biology, and Medicine; No. 34).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  2. Published

    Ultrastructure of precapillary sphincters and the neurovascular unit

    Grubb, Søren, 2023, In: Vascular Biology. 5, 1, 15 p., e230011.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Cellular Control of Brain Capillary Blood Flow: In Vivo Imaging Veritas

    Grutzendler, J. & Nedergaard, Maiken, 2019, In: Trends in Neurosciences. 42, 8, p. 528-536 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Anoxia increases potassium conductance in hippocampal nerve cells

    HANSEN, A. J., Hounsgaard, Jørn Dybkjær & Jahnsen, Henrik, Jul 1982, In: Acta Physiologica Scandinavica. 115, 3, p. 301-310 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia

    Hablitz, L. M., Vinitsky, H. S., Sun, Q., Stæger, Frederik Filip Vinggaard, Sigurdsson, B., Mortensen, K. N., Lilius, T. O. & Nedergaard, Maiken, 2019, In: Science Advances. 5, 2, 9 p., eaav5447.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The glymphatic system: A novel component of fundamental neurobiology

    Hablitz, L. M. & Nedergaard, Maiken, 2021, In: Journal of Neuroscience. 41, 37, p. 7698-7711 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  7. Published

    Circadian control of brain glymphatic and lymphatic fluid flow

    Hablitz, L. M., Plá, V., Giannetto, M., Vinitsky, H. S., Stæger, Frederik Filip Vinggaard, Metcalfe, T., Nguyen, R., Benrais, A. & Nedergaard, Maiken, 2020, In: Nature Communications. 11, 1, 4411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The endothelial border to health: Mechanistic evidence of the hyperglycemic culprit of inflammatory disease acceleration

    Hansen, N. W., Hansen, A. J. & Sams, A., Mar 2017, In: IUBMB Life. 69, 3, p. 148-161 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    Meningeal Lymphangiogenesis and Enhanced Glymphatic Activity in Mice with Chronically Implanted EEG Electrodes

    Hauglund, Natalie Linea, Kusk, P., Kornum, Birgitte Rahbek & Nedergaard, Maiken, 2020, In: Journal of Neuroscience. 40, 11, p. 2371-2380 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Cleaning the sleeping brain – the potential restorative function of the glymphatic system

    Hauglund, Natalie Linea, Pavan, C. & Nedergaard, Maiken, 1 Jun 2020, In: Current Opinion in Physiology. 15, 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Effect of sleep deprivation and NREM sleep stage on physiological brain pulsations

    Helakari, H., Järvelä, M., Väyrynen, T., Tuunanen, J., Piispala, J., Kallio, M., Ebrahimi, S. M., Poltojainen, V., Kananen, J., Elabasy, A., Huotari, N., Raitamaa, L., Tuovinen, T., Korhonen, V., Nedergaard, Maiken & Kiviniemi, V., 2023, In: Frontiers in Neuroscience. 17, 17 p., 1275184.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Human NREM Sleep Promotes Brain-Wide Vasomotor and Respiratory Pulsations

    Helakari, H., Korhonen, V., Holst, S. C., Piispala, J., Kallio, M., Väyrynen, T., Huotari, N., Raitamaa, L., Tuunanen, J., Kananen, J., Järvelä, M., Tuovinen, T., Raatikainen, V., Borchardt, V., Kinnunen, H., Nedergaard, Maiken & Kiviniemi, V., 2022, In: Journal of Neuroscience. 42, 12, p. 2503-2515 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Biophysical Modeling of Dopaminergic Denervation Landscapes in the Striatum Reveals New Therapeutic Strategy

    Heltberg, Mathias Spliid, Awada, H. N., Lucchetti, Alessandra, Jensen, Mogens Høgh, Dreyer, J. K. & Rasmussen, R. N., 2022, In: eNeuro. 9, 2, 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Brain lipidomics and neurodevelopmental outcomes in intrauterine growth restricted piglets fed dairy or vegetable fat diets

    Henriksen, Nicole Lind, Asmussen, K. S., Pan, X., Jiang, Pingping, Mori, Yuki, Christiansen, Line Iadsatian, Sprenger, R. R., Ejsing, C. S., Pankratova, Stanislava & Thymann, Thomas, 2022, In: Scientific Reports. 12, 1, 3303.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Glycogen distribution in mouse hippocampus

    Hirase, Hajime, Akther, S., Wang, X. & Oe, Y., 2019, In: Journal of Neuroscience Research. 97, 8, p. 923-932 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Locomotion Induces Fundamentally Different Patterns of Ca2+Signaling in Astrocytes and Neurons

    Hirase, Hajime & Nedergaard, Maiken, 2023, In: Function. 4, 4, 2 p., zqad028.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  17. Published

    Glia in Health and Disease

    Ho, M. S., Verkhratsky, A., Duan, S. & Parpura, V., 2019, In: Frontiers in Molecular Neuroscience. 12, 3 p., 63.

    Research output: Contribution to journal › Editorial › Research › peer-review

  18. Published

    Glymphatic influx and clearance are accelerated by neurovascular coupling: [Inkl. Correction]

    Holstein-Rønsbo, Stephanie, Gan, Y., Giannetto, M. J., Rasmussen, Martin Kaag, Sigurdsson, B., Beinlich, Felix Ralf Michael, Rose, Laura, Untiet, Verena, Hablitz, L. M., Kelley, D. H. & Nedergaard, Maiken, 2023, In: Nature Neuroscience. 26, p. 1042–1053

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The continued need for animals to advance brain research

    Homberg, J. R., Adan, R. A. H., Alenina, N., Asiminas, A., Bader, M., Beckers, T., Begg, D. P., Blokland, A., Burger, M. E., van Dijk, G., Eisel, U. L. M., Elgersma, Y., Englitz, B., Fernandez-Ruiz, A., Fitzsimons, C. P., van Dam, A-M., Gass, P., Grandjean, J., Havekes, R., Henckens, M. J. A. G. & 54 others, Herden, C., Hut, R. A., Jarrett, W., Jeffrey, K., Jezova, D., Kalsbeek, A., Kamermans, M., Kas, M. J., Kasri, N. N., Kiliaan, A. J., Kolk, S. M., Korosi, A., Korte, S. M., Kozicz, T., Kushner, S. A., Leech, K., Leech, K., Lesscher, H., Lucassen, P. J., Luthi, A., Ma, L., Mallien, A. S., Meerlo, P., Mejias, J. F., Meye, F. J., Mitchell, A. S., Mul, J. D., Olcese, U., Gonzalez, A. O., Oliver, J. D. A., Pasqualetti, M., Pennartz, C. A., Popik, P., Prickaerts, J., de la Prida, L. M., Ribeiro, S., Roozendaal, B., Rossato, J. I., Salari, A., Schoemaker, R. G., Smit, A. B., Takeuchi, T., van der Veen, R., Smidt, M. P., V. Vyazovskiy, V., Wiesmann, M., Wierenga, C. J., Williams, B., Willuhn, I., Woehr, M., Wolvekamp, M., van der Zee, E. A., Genzel, L. & Vanderschuren, L. J. M. J., 2021, In: Neuron. 109, 15, p. 2374-2379 6 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  20. Published

    Air pollution, glymphatic impairment, and Alzheimer's disease

    Hussain, R., Graham, U., Elder, A. & Nedergaard, Maiken, 2023, In: Trends in Neurosciences. 46, 11, p. 901-911 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    AMELIORATION OF GLYMPHATIC PATHWAY IS CRITICAL FOR LONG TERM RECOVERY FROM TRAUMATIC BRAIN INJURY

    Hussain, R., Wang, W., Cheetham-West, A. O., Sun, Q. & Nedergaard, Maiken, 2018, p. A204. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research

  22. Published

    EARLY ADDRESS OF POST-TRAUMATIC GLYMPHATIC INSUFFICIENCY REDUCES NEURONAL/GLIAL CELL DEATH AND TISSUE DAMAGES

    Hussain, R., Wang, W. & Nedergaard, Maiken, 2019, In: Journal of Neurotrauma. 36, 13, p. A-101 1 p., B04-05.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  23. Published

    Managing noradrenaline after traumatic brain injury

    Hussain, R. & Nedergaard, Maiken, 2024, In: Clinical and Translational Medicine. 14, 1, 3 p., e1562.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  24. Published

    Potentiating glymphatic drainage minimizes post-traumatic cerebral oedema

    Hussain, R., Tithof, J., Wang, W., Cheetham-West, A., Song, W., Peng, W., Sigurdsson, B., Kim, D., Sun, Q., Peng, S., Pla Requena, Virginia Teresa, Kelley, D. H., Hirase, Hajime, Castorena-Gonzalez, J. A., Weikop, Pia, Goldman, Steven Alan, Davis, M. J. & Nedergaard, Maiken, 2023, In: Nature. 623, p. 992–1000 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts

    Hyun, I., Clayton, E. W., Cong, Y., Fujita, M., Goldman, Steven Alan, Hill, L. R., Monserrat, N., Nakauchi, H., Pedersen, R. A., Rooke, H. M., Takahashi, J. & Knoblich, J. A., 2021, In: Stem Cell Reports. 16, 6, p. 1409-1415 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    Implications of the discovery of brain lymphatic pathways

    Iliff, J. J., Goldman, Steven Alan & Nedergaard, Maiken, 2015, In: Lancet Neurology. 14, 10, p. 977-979 3 p.

    Research output: Contribution to journal › Journal article › Communication

  27. Published

    Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement

    Iwai, Y., Ozawa, K., Yahagi, K., Mishima, Tsuneko, Akther, S., Vo, C. T., Lee, Ashley Bomin, Tanaka, M., Itohara, S. & Hirase, Hajime, 2021, In: Frontiers in Neural Circuits. 15, 16 p., 658343.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Astrocytes in chronic pain and itch

    Ji, R., Donnelly, C. R. & Nedergaard, Maiken, 2019, In: Nature Reviews Neuroscience. 20, 11, p. 667-685

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    Impairment of the glymphatic system after diabetes

    Jiang, Q., Zhang, L., Ding, G., Davoodi-Bojd, E., Li, Q., Li, L., Sadry, N., Nedergaard, Maiken, Chopp, M. & Zhang, Z., 1 Apr 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 4, p. 1326-1337 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    An fMRI-compatible system for targeted electrical stimulation

    Jørgensen, Louise Møller, Baandrup, A. O., Mandeville, J., Glud, A. N., Sørensen, J. C. H., Weikop, Pia, Jespersen, B., Hansen, Adam Espe, Thomsen, C. & Knudsen, Gitte Moos, 2022, In: Journal of Neuroscience Methods. 378, 109659.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Increased interictal synchronicity of respiratory related brain pulsations in epilepsy

    Kananen, J., Järvelä, M., Korhonen, V., Tuovinen, T., Huotari, N., Raitamaa, L., Helakari, H., Väyrynen, T., Raatikainen, V., Nedergaard, Maiken, Ansakorpi, H., Jacobs, J., LeVan, P. & Kiviniemi, V., 2022, In: Journal of Cerebral Blood Flow and Metabolism. 42, 10, p. 1840-1853 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Altered physiological brain variation in drug-resistant epilepsy

    Kananen, J., Tuovinen, T., Ansakorpi, H., Rytky, S., Helakari, H., Huotari, N., Raitamaa, L., Raatikainen, V., Rasila, A., Borchardt, V., Korhonen, V., LeVan, P., Nedergaard, Maiken & Kiviniemi, V., 2018, In: Brain and Behavior. 8, 9, p. 1-17 17 p., e01090.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Respiratory-related brain pulsations are increased in epilepsy-a two-centre functional MRI study

    Kananen, J., Helakari, H., Korhonen, V., Huotari, N., Jarvela, M., Raitamaa, L., Raatikainen, V., Rajna, Z., Tuovinen, T., Nedergaard, Maiken, Jacobs, J., LeVan, P., Ansakorpi, H. & Kiviniemi, V., 2020, In: Brain Communications. 2, 2, 14 p., 076.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets

    Karimy, J. K., Reeves, B. C., Damisah, E., Duy, P. Q., Antwi, P., David, W., Wang, K., Schiff, S. J., Limbrick, D. D. ,. J., Alper, S. L., Warf, B. C., Nedergaard, Maiken, Simard, J. M. & Kahle, K. T., 2020, In: Nature Reviews Neurology. 16, p. 285–296 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  35. Published

    An immortalized human adipose-derived stem cell line with highly enhanced chondrogenic properties

    Katz, D. B., Huynh, N. P. T., Savadipour, A., Palte, I. & Guilak, F., 2020, In: Biochemical and Biophysical Research Communications. 530, 1, p. 252-258 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Astrocytic contributions to Huntington's disease pathophysiology

    Khakh, B. S. & Goldman, Steven Alan, 2023, In: Annals of the New York Academy of Sciences. 1522, 1, p. 42-59 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  37. Published

    Unravelling and Exploiting Astrocyte Dysfunction in Huntington's Disease

    Khakh, B. S., Beaumont, V., Cachope, R., Munoz-Sanjuan, I., Goldman, Steven Alan & Grantyn, R., Jul 2017, In: Trends in Neurosciences. 40, 7, p. 422-437 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    Repeated low doses of psilocybin increase resilience to stress, lower compulsive actions, and strengthen cortical connections to the paraventricular thalamic nucleus in rats

    Kiilerich, K. F., Lorenz, J., Scharff, M. B., Speth, N., Brandt, T. G., Czurylo, J., Xiong, M., Jessen, N. S., Casado-Sainz, A., Shalgunov, Vladimir, Kjærby, Celia, Satała, G., Bojarski, A. J., Jensen, Anders A., Herth, Matthias Manfred, Cumming, P., Overgaard, A. & Palner, M., 2023, In: Molecular Psychiatry. 28, 9, p. 3829-3841

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Donor cell memory confers a metastable state of directly converted cells

    Kim, K. P., Li, C., Bunina, D., Jeong, H. W., Ghelman, J., Yoon, J., Shin, B., Park, H., Han, D. W., Zaugg, J. B., Kim, J., Kuhlmann, T., Adams, R. H., Noh, K. M., Goldman, Steven Alan & Schöler, H. R., 2021, In: Cell Stem Cell. 28, 7, p. 1291-1306.e10 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Does Global Astrocytic Calcium Signaling Participate in Awake Brain State Transitions and Neuronal Circuit Function?

    Kjærby, Celia, Rasmussen, R., Andersen, Mie & Nedergaard, Maiken, Jun 2017, In: Neurochemical Research. 42, 6, p. 1810-1822 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine

    Kjærby, Celia, Andersen, Mie, Hauglund, Natalie Linea, Untiet, Verena, Dall, C., Sigurdsson, B., Ding, F., Feng, J., Li, Y., Weikop, Pia, Hirase, Hajime & Nedergaard, Maiken, 2022, In: Nature Neuroscience. 25, p. 1059–1070 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Impaired GABAergic Inhibition in the Prefrontal Cortex of Early Postnatal Phencyclidine (PCP)-Treated Rats

    Kjærby, Celia, Broberg, B. V., Kristiansen, Uffe & Dalby, N. O., 2014, In: Cerebral Cortex. 24, 9, p. 2522-32 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Dynamic fluctuations of the locus coeruleus-norepinephrine system underlie sleep state transitions

    Kjærby, Celia, Andersen, Mie, Hauglund, Natalie Linea, Ding, F., Wang, W., Xu, Q., Deng, S., Kang, N., Peng, S., Sun, Q., Dall, C., Jørgensen, P. K., Feng, J., Li, Y., Weikop, Pia, Hirase, Hajime & Nedergaard, Maiken, 2 Sep 2020, 1 p.

    Research output: Other contribution › Research

  44. Published

    Reply to: 'Do all norepinephrine surges disrupt sleep?'

    Kjærby, Celia, Andersen, Mie, Hauglund, Natalie Linea, Untiet, Verena, Dall, C., Ding, F., Hirase, Hajime & Nedergaard, Maiken, 2023, In: Nature Neuroscience. 26, 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  45. Published

    Introducing the special issue on “Proteins and Circuits in Memory”

    Kjærgaard, M., Petersen, Nicolas Caesar, Sørensen, Jakob Balslev & Takeuchi, T., 2021, In: European Journal of Neuroscience. 54, 8, p. 6691-6695 5 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  46. Published

    Human glial chimeric mice reveal astrocytic dependence of JC virus infection

    Kondo, Y., Windrem, M. S., Zou, L., Chandler-Militello, D., Schanz, S. J., Auvergne, R. M., Betstadt, S. J., Harrington, A. R., Johnson, M., Kazarov, A., Gorelik, L. & Goldman, Steven Alan, 1 Dec 2014, In: The Journal of Clinical Investigation. 124, 12, p. 5323-36 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Brain Morphometry and Longitudinal Relaxation Time of Spontaneously Hypertensive Rats (SHRs) in Early and Intermediate Stages of Hypertension Investigated by 3D VFA-SPGR MRI

    Koundal, S., Liu, X., Sanggaard, S., Mortensen, K., Wardlaw, J., Nedergaard, Maiken, Benveniste, H. & Lee, H., 2019, In: Neuroscience. 404, p. 14-26

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Increased activity of glial glutamate transporter-associated anion channels results in episodic ataxia 6

    Kovermann, P., Untiet, Verena, Kolobkova, Y. & Fahlke, C., 2019, In: Glia. 67, S1, p. E216 1 p., T05-034A.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  49. Published

    EARLY INTRODUCTION TO HIGH-INTENSITY INTERVAL TRAINING IN STROKE ASSOCIATES WITH SUSTAINED VIGOROUS-INTENSITY ACTIVITY AT LONG-TERM FOLLOW-UP - RESULTS FROM THE HITPALS STUDY

    Krawcyk, R. S., Vinther, A., Petersen, Nicolas Caesar, Faber, Jens, Iversen, Helle Klingenberg, Christensen, T., Lambertsen, K., Klausen, T., Rostrup, E. & Kruuse, Christina Rostrup, 2020, In: International Journal of Stroke. 15, Supplement 1, p. 132 00477 / #2449.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  50. Published

    Effect of Home-Based High-Intensity Interval Training in Patients With Lacunar Stroke: A Randomized Controlled Trial

    Krawcyk, R. S., Vinther, A., Petersen, Nicolas Caesar, Faber, Jens, Iversen, Helle Klingenberg, Christensen, T., Lambertsen, K. L., Rehman, S., Klausen, T. W., Rostrup, E. & Kruuse, Christina Rostrup, 2019, In: Frontiers in Neurology. 10, 15 p., 664.

    Research output: Contribution to journal › Journal article › Research › peer-review

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