Center for Translational Neuromedicine

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  1. Published

    The Alzheimer's disease 5xFAD mouse model is best suited to investigate pretargeted imaging approaches beyond the blood-brain barrier

    Lopes van den Broek, S. I., Sehlin, D., Andersen, Jens Velde, Aldana, Blanca, Beschorner, Natalie, Nedergaard, Maiken, Knudsen, Gitte Moos, Syvanen, S. & Herth, Matthias Manfred, 2023, In: Frontiers in Nuclear Medicine. 2, 7 p., 1001722.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier

    Lou, N., Takano, T., Pei, Y., L R Xavier, Anna , Goldman, Steven Alan & Nedergaard, Maiken, 26 Jan 2016, In: National Academy of Sciences. Proceedings. 113, 4, p. 1074-1079 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Understanding the functions and relationships of the glymphatic system and meningeal lymphatics

    Louveau, A., Plog, B. A., Antila, S., Alitalo, K., Nedergaard, Maiken & Kipnis, J., 1 Sep 2017, In: The Journal of Clinical Investigation. 127, 9, p. 3210-3219 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update

    Lovell-Badge, R., Anthony, E., Barker, R. A., Bubela, T., Brivanlou, A. H., Carpenter, M., Charo, R. A., Clark, A., Clayton, E., Cong, Y., Daley, G. Q., Fu, J., Fujita, M., Greenfield, A., Goldman, S. A., Hill, L., Hyun, I., Isasi, R., Kahn, J., Kato, K. & 27 others, Kim, J. S., Kimmelman, J., Knoblich, J. A., Mathews, D., Montserrat, N., Mosher, J., Munsie, M., Nakauchi, H., Naldini, L., Naughton, G., Niakan, K., Ogbogu, U., Pedersen, R., Rivron, N., Rooke, H., Rossant, J., Round, J., Saitou, M., Sipp, D., Steffann, J., Sugarman, J., Surani, A., Takahashi, J., Tang, F., Turner, L., Zettler, P. J. & Zhai, X., 2021, In: Stem Cell Reports. 16, 6, p. 1398-1408 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  5. Published

    Glymphatic clearance controls state-dependent changes in brain lactate concentration

    Lundgaard, I., Lu, M. L., Yang, E., Peng, W., Mestre, H., Hitomi, E., Deane, R. & Nedergaard, Maiken, Jun 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 6, p. 2112-2124 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Direct neuronal glucose uptake Heralds activity-dependent increases in cerebral metabolism

    Lundgaard, I., Li, B., Xie, L., Kang, H., Sanggaard, S., Haswell, J. D. R., Sun, W., Goldman, S., Blekot, S., Nielsen, Michael Lund, Takano, T., Deane, R. & Nedergaard, Maiken, 2015, In: Nature Communications. 6, 12 p., 6807.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function

    Lundgaard, I., Wang, W., Eberhardt, A., Vinitsky, H. S., Reeves, B. C., Peng, S., Lou, N., Hussain, R. & Nedergaard, Maiken, 2018, In: Scientific Reports. 8, 1, 16 p., 2246.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Psilocybin-induced reduction in chronic cluster headache attack frequency correlates with changes in hypothalamic functional connectivity

    Madsen, M. K., Petersen, A. S., Stenbæk, Dea Siggaard, Sorensen, I. M., Schionning, H., Fjeld, T., Nykjaer, C., Larsen, S. M. U., Grzywacz, M., Mathiesen, T., Klausen, I., Hansen, O. O., Brendstrup-Brix, K., Linnet, Kristian, Johansen, Sys Stybe, Fisher, P. M., Jensen, Rasmus Herlo Beenfeldt, Knudsen, Gitte Moos & Madsen, M. K., 2022, medRxiv, 17 p.

    Research output: Working paper › Preprint › Research

  9. Published

    Derivation of telencephalic oligodendrocyte progenitors from human pluripotent stem cells

    Major, T., Powers, A. & Tabar, V., Nov 2016, In: Current Protocols in Stem Cell Biology. 39, 1, p. 1H.10.1-1H.10.23 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Human Glial Chimeric Mice to Define the Role of Glial Pathology in Human Disease

    Mariani, J. N., Zou, L. & Goldman, Steven Alan, 2019, Oligodendrocytes. Springer, Vol. 1936. p. 311-331 21 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  11. Published

    TUBE project: Transport-derived ultrafines and the brain effects

    Martikainen, M. V., Aakko-Saksa, P., Broek, L. V. D., Cassee, F. R., Carare, R. O., Chew, S., Dinnyes, A., Giugno, R., Kanninen, K. M., Malm, T., Muala, A., Nedergaard, M., Oudin, A., Oyola, P., Pfeiffer, T. V., Rönkkö, T., Saarikoski, S., Sandström, T., Schins, R. P. F., Topinka, J. & 4 others, Yang, M., Zeng, X., Westerink, R. H. S. & Jalava, P. I., 2022, In: International Journal of Environmental Research and Public Health. 19, 1, 14 p., 311.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Disruption of Semantic Network in Mild Alzheimer's Disease Revealed by Resting-State fMRI

    Mascali, D., DiNuzzo, M., Serra, L., Mangia, S., Maraviglia, B., Bozzali, M. & Giove, F., 2018, In: Neuroscience. 371, p. 38-48 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice

    Mathiesen, B. K., Miyakoshi, L. M., Cederroth, C. R., Tserga, E., Versteegh, C., Bork, Peter Aleksander Rousing, Hauglund, Natalie Linea, Gomolka, Ryszard Stefan, Mori, Yuki, Edvall, N. K., Rouse, S., Møllgård, Kjeld, Holt, J. R., Nedergaard, Maiken & Canlon, B., 2023, In: Science Translational Medicine. 15, 702, 13 p., eabq3916.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The Brain's Glymphatic System: Current Controversies

    Mestre, H., Mori, Yuki & Nedergaard, Maiken, 2020, In: Trends in Neurosciences. 43, 7, p. 458-466 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Cerebrospinal fluid influx drives acute ischemic tissue swelling

    Mestre, H., Du, T., Sweeney, A. M., Liu, G., Samson, A. J., Peng, W., Mortensen, K. N., Stæger, F. F., Bork, P. A. R., Bashford, L., Toro, E. R., Tithof, J., Kelley, D. H., Thomas, J. H., Hjorth, P. G., Martens, E. A., Mehta, R. I., Solis, O., Blinder, P., Kleinfeld, D. & 3 others, Hirase, Hajime, Mori, Yuki & Nedergaard, Maiken, 2020, In: Science. 367, 6483, 8 p., eaaw7462.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Aquaporin-4-dependent glymphatic solute transport in the rodent brain

    Mestre, H., Hablitz, L. M., Xavier, A. L. R., Feng, W., Zou, W., Pu, T., Monai, H., Murlidharan, G., Rivera, R. M. C., Simon, M. J., Pike, M. M., Pla, V., Du, T., Kress, B. T., Wang, X., Plog, B. A., Thrane, A. S., Lundgaard, I., Abe, Y., Yasui, M. & 6 others, Thomas, J. H., Xiao, M., Hirase, Hajime, Asokan, A., Iliff, J. J. & Nedergaard, Maiken, 2018, In: eLife. 7, 31 p., :e40070.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Perivascular spaces, glymphatic dysfunction, and small vessel disease

    Mestre, H., Kostrikov, S., Mehta, R. I. & Nedergaard, Maiken, 1 Sep 2017, In: Clinical Science. 131, 17, p. 2257-2274 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension

    Mestre, H., Tithof, J., Du, T., Song, W., Peng, W., Sweeney, A. M., Olveda, G., Thomas, J. H., Nedergaard, Maiken & Kelley, D. H., 2018, In: Nature Communications. 9, 1, 9 p., 4878.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Periarteriolar spaces modulate cerebrospinal fluid transport into brain and demonstrate altered morphology in aging and Alzheimer’s disease

    Mestre, H., Verma, N., Greene, T. D., Lin, L. J. A., Ladron-de-Guevara, A., Sweeney, A. M., Liu, G., Thomas, V. K., Galloway, C. A., de Mesy Bentley, K. L., Nedergaard, Maiken & Mehta, R. I., 2022, In: Nature Communications. 13, 1, 8 p., 3897.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Quantitative determination of cellular [Na+] by fluorescence lifetime imaging with CoroNaGreen

    Meyer, J., Untiet, Verena, Fahlke, C., Gensch, T. & Rose, C. R., 2019, In: Journal of General Physiology. 151, 11, p. 1319-1331

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Surface periarterial spaces of the mouse brain are open, not porous

    Min Rivas, F., Liu, J., Martell, B. C., Du, T., Mestre, H., Nedergaard, Maiken, Tithof, J., Thomas, J. H. & Kelley, D. H., 2020, In: Journal of the Royal Society, Interface. 17, 172, 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Transcranial Direct Current Stimulation (tDCS Induces Adrenergic Receptor-Dependent Microglial Morphological Changes in Mice

    Mishima, T., Nagai, T., Yahagi, K., Akther, S., Oe, Y., Monai, H., Kohsaka, S. & Hirase, Hajime, 2019, In: eNeuro. 6, 5, 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The state of brain activity modulates cerebrospinal fluid transport

    Miyakoshi, L. M., Stæger, Frederik Filip Vinggaard, Li, Q., Pan, C., Xie, L., Kang, H., Pavan, C., Dang, J., Sun, Q., Ertürk, A. & Nedergaard, Maiken, 2023, In: Progress in Neurobiology. 229, 11 p., 102512.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The Glymphatic System (En)during Inflammation

    Mogensen, F. L., Delle, Christine & Nedergaard, Maiken, 2021, In: International Journal of Molecular Sciences. 22, 14, 20 p., 7491.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis

    Mohanty, T., Fisher, J., Bakochi, A., Neumann, A., Cardoso, J. F. P., Karlsson, C. A. Q., Pavan, C., Lundgaard, I., Nilson, B., Reinstrup, P., Bonnevier, J., Cederberg, D., Malmström, J., Bentzer, P. & Linder, A., 2019, In: Nature Communications. 10, 13 p., 1667.

    Research output: Contribution to journal › Journal article › Research › peer-review

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