Glymphatic system

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Standard

Glymphatic system. / Benveniste, Helene; Nedergaard, Maiken.

Neuroscience in the 21st Century: From Basic to Clinical. 2. ed. Springer, 2016. p. 1945-1962.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Harvard

Benveniste, H & Nedergaard, M 2016, Glymphatic system. in Neuroscience in the 21st Century: From Basic to Clinical. 2 edn, Springer, pp. 1945-1962. https://doi.org/10.1007/978-1-4939-3474-4_138

APA

Benveniste, H., & Nedergaard, M. (2016). Glymphatic system. In Neuroscience in the 21st Century: From Basic to Clinical (2 ed., pp. 1945-1962). Springer. https://doi.org/10.1007/978-1-4939-3474-4_138

Vancouver

Benveniste H, Nedergaard M. Glymphatic system. In Neuroscience in the 21st Century: From Basic to Clinical. 2 ed. Springer. 2016. p. 1945-1962 https://doi.org/10.1007/978-1-4939-3474-4_138

Author

Benveniste, Helene ; Nedergaard, Maiken. / Glymphatic system. Neuroscience in the 21st Century: From Basic to Clinical. 2. ed. Springer, 2016. pp. 1945-1962

Bibtex

@inbook{70d6c2e748af43018492d1c5b128531f,
title = "Glymphatic system",
abstract = "The brain is one of the most metabolically active organs in the body, and continuous removal of excess fluid and waste products is critical for normal brain function. In contrast to other body organs, the brain lack lymphatic vessels for detoxification. In place of lymphatic vessels, the brain uses a so-called glymphatic pathway which comprise the peri-vascular space and acuaporin-4 water channels on astroglial endfeet. As such the glymphatic pathway can be perceived as a hitherto overlooked compartment of the extracellular space of the central nervous system which is involved in clearance of amyloid-beta and other neurotoxic waste substances that build up in the brain.",
keywords = "AQP4 water channels, AQP4 water channels, polarity and density of, Aquaporin-4 (AQP4) water channels, Blood-brain barrier (BBB), Body posture, Cerebrospinal fluid (CSF), Chronic traumatic encephalopathy (CTE), CSF-ISF, efflux pathways, Glymphatic system, Horseradish peroxidase (HRP), Interstitial fluid (ISF), Interstitial space size, Protein waste products, removal of, TBI, Traumatic brain injury (TBI), Vascular pulsatility",
author = "Helene Benveniste and Maiken Nedergaard",
year = "2016",
doi = "10.1007/978-1-4939-3474-4_138",
language = "English",
isbn = "978-1-4939-3473-7",
pages = "1945--1962",
booktitle = "Neuroscience in the 21st Century",
publisher = "Springer",
address = "Switzerland",
edition = "2",

}

RIS

TY - CHAP

T1 - Glymphatic system

AU - Benveniste, Helene

AU - Nedergaard, Maiken

PY - 2016

Y1 - 2016

N2 - The brain is one of the most metabolically active organs in the body, and continuous removal of excess fluid and waste products is critical for normal brain function. In contrast to other body organs, the brain lack lymphatic vessels for detoxification. In place of lymphatic vessels, the brain uses a so-called glymphatic pathway which comprise the peri-vascular space and acuaporin-4 water channels on astroglial endfeet. As such the glymphatic pathway can be perceived as a hitherto overlooked compartment of the extracellular space of the central nervous system which is involved in clearance of amyloid-beta and other neurotoxic waste substances that build up in the brain.

AB - The brain is one of the most metabolically active organs in the body, and continuous removal of excess fluid and waste products is critical for normal brain function. In contrast to other body organs, the brain lack lymphatic vessels for detoxification. In place of lymphatic vessels, the brain uses a so-called glymphatic pathway which comprise the peri-vascular space and acuaporin-4 water channels on astroglial endfeet. As such the glymphatic pathway can be perceived as a hitherto overlooked compartment of the extracellular space of the central nervous system which is involved in clearance of amyloid-beta and other neurotoxic waste substances that build up in the brain.

KW - AQP4 water channels

KW - AQP4 water channels, polarity and density of

KW - Aquaporin-4 (AQP4) water channels

KW - Blood-brain barrier (BBB)

KW - Body posture

KW - Cerebrospinal fluid (CSF)

KW - Chronic traumatic encephalopathy (CTE)

KW - CSF-ISF, efflux pathways

KW - Glymphatic system

KW - Horseradish peroxidase (HRP)

KW - Interstitial fluid (ISF)

KW - Interstitial space size

KW - Protein waste products, removal of

KW - TBI

KW - Traumatic brain injury (TBI)

KW - Vascular pulsatility

U2 - 10.1007/978-1-4939-3474-4_138

DO - 10.1007/978-1-4939-3474-4_138

M3 - Book chapter

AN - SCOPUS:85018935128

SN - 978-1-4939-3473-7

SP - 1945

EP - 1962

BT - Neuroscience in the 21st Century

PB - Springer

ER -

ID: 179090042