Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain?

Research output: Contribution to journal › Journal article › Research › peer-review

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Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain? / Oberheim Bush, Nancy Ann; Nedergaard, Maiken.

In: Neurochemical Research, Vol. 42, No. 9, 09.2017, p. 2577-2587.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Oberheim Bush, NA & Nedergaard, M 2017, 'Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain?', Neurochemical Research, vol. 42, no. 9, pp. 2577-2587. https://doi.org/10.1007/s11064-017-2363-0

APA

Oberheim Bush, N. A., & Nedergaard, M. (2017). Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain? Neurochemical Research, 42(9), 2577-2587. https://doi.org/10.1007/s11064-017-2363-0

Vancouver

Oberheim Bush NA, Nedergaard M. Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain? Neurochemical Research. 2017 Sep;42(9):2577-2587. https://doi.org/10.1007/s11064-017-2363-0

Author

Oberheim Bush, Nancy Ann ; Nedergaard, Maiken. / Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain?. In: Neurochemical Research. 2017 ; Vol. 42, No. 9. pp. 2577-2587.

Bibtex

@article{d50572ed3d884f1d94ee010cba3ec6d1,
title = "Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain?",
abstract = "It is now well accepted that astrocytes are essential in all major nervous system functions of the rodent brain, including neurotransmission, energy metabolism, modulation of blood flow, ion and water homeostasis, and, indeed, higher cognitive functions, although the contribution of astrocytes in cognition is still in early stages of study. Here we review the most current research findings on human astrocytes, including their structure, molecular characterization, and functional properties. We also highlight novel tools that have been established for translational approaches to the comparative study of astrocytes from humans and experimental animals. Understanding the differences in astrocytes is essential to elucidate the contribution of astrocytes to normal physiology, cognitive processing and diverse pathologies of the central nervous system.",
keywords = "Journal Article",
author = "{Oberheim Bush}, {Nancy Ann} and Maiken Nedergaard",
year = "2017",
month = sep,
doi = "10.1007/s11064-017-2363-0",
language = "English",
volume = "42",
pages = "2577--2587",
journal = "Neurochemical Research",
issn = "0364-3190",
publisher = "Springer",
number = "9",

}

RIS

TY - JOUR

T1 - Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain?

AU - Oberheim Bush, Nancy Ann

AU - Nedergaard, Maiken

PY - 2017/9

Y1 - 2017/9

N2 - It is now well accepted that astrocytes are essential in all major nervous system functions of the rodent brain, including neurotransmission, energy metabolism, modulation of blood flow, ion and water homeostasis, and, indeed, higher cognitive functions, although the contribution of astrocytes in cognition is still in early stages of study. Here we review the most current research findings on human astrocytes, including their structure, molecular characterization, and functional properties. We also highlight novel tools that have been established for translational approaches to the comparative study of astrocytes from humans and experimental animals. Understanding the differences in astrocytes is essential to elucidate the contribution of astrocytes to normal physiology, cognitive processing and diverse pathologies of the central nervous system.

AB - It is now well accepted that astrocytes are essential in all major nervous system functions of the rodent brain, including neurotransmission, energy metabolism, modulation of blood flow, ion and water homeostasis, and, indeed, higher cognitive functions, although the contribution of astrocytes in cognition is still in early stages of study. Here we review the most current research findings on human astrocytes, including their structure, molecular characterization, and functional properties. We also highlight novel tools that have been established for translational approaches to the comparative study of astrocytes from humans and experimental animals. Understanding the differences in astrocytes is essential to elucidate the contribution of astrocytes to normal physiology, cognitive processing and diverse pathologies of the central nervous system.

KW - Journal Article

U2 - 10.1007/s11064-017-2363-0

DO - 10.1007/s11064-017-2363-0

M3 - Journal article

C2 - 28822066

VL - 42

SP - 2577

EP - 2587

JO - Neurochemical Research

JF - Neurochemical Research

SN - 0364-3190

IS - 9

ER -

ID: 185945278