Center for Translational Neuromedicine

  1. 2019
  2. Published

    Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke

    Monai, H., Wang, X., Yahagi, K., Lou, N., Mestre, H., Xu, Q., Abe, Y., Yasui, M., Iwai, Y., Nedergaard, Maiken & Hirase, Hajime, 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 22, p. 11010-11019 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    PDGF-B Is Required for Development of the Glymphatic System

    Munk, A. S., Wang, W., Bèchet, N. B., Eltanahy, A. M., Cheng, A. X., Sigurdsson, B., Benraiss, A., Mäe, M. A., Kress, B. T., Kelley, D. H., Betsholtz, C., Møllgård, Kjeld, Meissner, A., Nedergaard, Maiken & Lundgaard, I., 2019, In: Cell Reports. 26, 11, p. 2955-2969.e3 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The glymphatic system: reactive gliosis as a negative regulator

    Nedergaard, Maiken, 2019, In: Glia. 67, S1, p. E91 1 p., S26-02.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  5. Published

    Direct conversion of hESC-derived glial progenitors into midbrain dopaminergic neurons

    Nolbrant, S., Hoban, D., Giacomoni, J., Ottosson, D. R., Goldman, Steven Alan & Parmar, M., 2019, In: Glia. 67, S1, p. E662-E663 2 p., T16-015B.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  6. Published

    Impaired Glymphatic Transport in Spontaneously Hypertensive Rats

    Nygaard Mortensen, K., Sanggaard, S., Mestre, H., Lee, H., Kostrikov, S., L R Xavier, Anna , Gjedde, Albert, Benveniste, H. & Nedergaard, Maiken, 2019, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 32, p. 6365-6377 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Human ESC-Derived Chimeric Mouse Models of Huntington's Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation

    Osipovitch, M., Martinez, A. A., Mariani, J. N., Cornwell, A., Dhaliwal, S., Zou, L., Chandler-Militello, D., Wang, S., Li, X., Benraiss, S., Agate, R., Lampp, A., Benraiss, A., Windrem, M. S. & Goldman, Steven Alan, 2019, In: Cell Stem Cell. 24, 1, p. 107-122.e7

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The intrinsic effects of EIF2B mutations in human Vanishing White Matter-derived glial progenitor cells

    Osorio, M. J., Lassen, Mette, Kristine, M. & Goldman, Steven Alan, 2019, In: Glia. 67, S1, p. E312-E313 2 p., T08-031A.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  9. Published

    Cisterna magna injection in rats to study glymphatic function

    Ramos, M., Burdon Bechet, N., Battistella, R., Pavan, C., L R Xavier, Anna , Nedergaard, Maiken & Lundgaard, I., 2019, Astrocytes: Methods and Protocols. Di Benedetto, B. (ed.). Humana Press, p. 97-104 8 p. (Methods in Molecular Biology, Vol. 1938).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  10. Published

    Cortex-wide Changes in Extracellular Potassium Ions Parallel Brain State Transitions in Awake Behaving Mice

    Rasmussen, R., Nicholas, E., Petersen, Nicolas Caesar, Dietz, Andrea Grostøl, Xu, Q., Sun, Q. & Nedergaard, Maiken, 2019, In: Cell Reports. 28, 5, p. 1182-1194 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    SPECT imaging of the glymphatic pathway with In-111-labeled ovalbumin in the rat brain

    Shalgunov, Vladimir, Lilius, T., Sigurosson, B., Baerentzen, S. L., Hauglund, Natalie Linea, Herth, Matthias Manfred, Palner, M. & Nedergaard, Maiken, 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supplement 1, p. S404-S405 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  12. Published

    In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy

    Sweeney, A. M., Pla, V., Du, T., Liu, G., Sun, Q., Peng, S., Plog, B. A., Kress, B. T., Wang, X., Mestre, H. & Nedergaard, Maiken, 2019, In: Journal of Visualized Experiments. 149, 7 p., e59774.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Vascular dysfunction-The disregarded partner of Alzheimer's disease

    Sweeney, M. D., Montagne, A., Sagare, A. P., Nation, D. A., Schneider, L. S., Chui, H. C., Harrington, M. G., Pa, J., Law, M., Wang, D. J. J., Jacobs, R. E., Doubal, F. N., Ramirez, J., Black, S. E., Nedergaard, M., Benveniste, H., Dichgans, M., Iadecola, C., Love, S., Bath, P. M. & 49 others, Markus, H. S., Salman, R. A., Allan, S. M., Quinn, T. J., Kalaria, R. N., Werring, D. J., Carare, R. O., Touyz, R. M., Williams, S. C. R., Moskowitz, M. A., Katusic, Z. S., Lutz, S. E., Lazarov, O., Minshall, R. D., Rehman, J., Davis, T. P., Wellington, C. L., Gonzalez, H. M., Yuan, C., Lockhart, S. N., Hughes, T. M., Chen, C. L. H., Sachdev, P., O'Brien, J. T., Skoog, I., Pantoni, L., Gustafson, D. R., Biessels, G. J., Wallin, A., Smith, E. E., Mok, V., Wong, A., Passmore, P., Barkof, F., Muller, M., Breteler, M. M. B., Roman, G. C., Hamel, E., Seshadri, S., Gottesman, R. F., van Buchem, M. A., Arvanitakis, Z., Schneider, J. A., Drewes, L. R., Hachinski, V., Finch, C. E., Toga, A. W., Wardlaw, J. M. & Zlokovic, B. V., 2019, In: Alzheimers & Dementia. 15, 1, p. 158-167

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Design of gadoteridol-loaded cationic liposomal adjuvant CAF01 for MRI of lung deposition of intrapulmonary administered particles

    Thakur, A., Rose, F., Ansari, S. R., Koch, P., Martini, V., Ovesen, S. L., Quistorff, B., Maritim, S., Hyder, F., Andersen, Peter, Christensen, D., Mori, Yuki & Foged, Camilla, 2019, In: Molecular Pharmaceutics. 16, 11, p. 4725-4737 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Gliocrine System: Astroglia as Secretory Cells of the CNS

    Vardjan, N., Parpura, V., Verkhratsky, A. & Zorec, R., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 93-115 23 p. (Advances in Experimental Medicine and Biology, Vol. 1175).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    Astroglia in Alzheimer’s Disease

    Verkhratsky, A., Parpura, V., Rodriguez-Arellano, J. J. & Zorec, R., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 273-324 52 p. (Advances in Experimental Medicine and Biology, Vol. 1175).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  17. Published

    Astroglial Calcium Signaling in Aging and Alzheimer's Disease

    Verkhratsky, A., 2019, In: Cold Spring Harbor perspectives in biology. 11, 7, 16 p., a035188 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Astroglial signalling in health and disease

    Verkhratsky, A. & Zorec, R., 2019, In: Neuroscience Letters. 689, p. 1-4 4 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  19. Published

    Evolution of Neuroglia

    Verkhratsky, A., Ho, M. S. & Parpura, V., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 15-44 30 p. (Advances in Experimental Medicine and Biology, Vol. 1175).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  20. Published

    General Pathophysiology of Astroglia

    Verkhratsky, A., Ho, M. S., Vardjan, N., Zorec, R. & Parpura, V., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 149-179 31 p. (Advances in Experimental Medicine and Biology, Vol. 1175).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  21. Published

    Neuroglia in ageing

    Verkhratsky, A., Zorec, R., Rodriguez-Arellano, J. J. & Parpura, V., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 181-197 17 p. (Advances in Experimental Medicine and Biology, Vol. 1175).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  22. Published

    Physiology of Astroglia

    Verkhratsky, A., Parpura, V., Vardjan, N. & Zorec, R., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 45-91 47 p. (Advances in Experimental Medicine and Biology, Vol. 1175).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  23. Published

    The Concept of Neuroglia

    Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V., 2019, Neuroglia in Neurodegenerative Diseases. Verkhratsky, A., Ho, M. S., Zorec, R. & Parpura, V. (eds.). Springer, p. 1-13 13 p. (Advances in Experimental Medicine and Biology, Vol. 1175).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  24. Published

    Astrocytic connexin 43 potentiates myelin injury in ischemic white matter disease

    Wang, M., Qin, C., Luo, X., Wang, J., Wang, X., Xie, M., Hu, J., Cao, J., Hu, T., Goldman, Steven Alan, Nedergaard, Maiken & Wang, W., 2019, In: Theranostics. 9, 15, p. 4474-4493 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The Ocular Glymphatic Clearance System

    Wang, X., Lou, N., Eberhardt, A., Jørgensen, P. K., Xu, Q., Foerstera, B., Peng, S., Yang, Y., Shi, M., L R Xavier, Anna , Ertürk, A., Libby, R. T., Lu, C., Thrane, A. & Nedergaard, Maiken, 30 Dec 2019, bioRxiv, 23 p.

    Research output: Working paperPreprintResearch

  26. Published

    Pioglitazone reversed the fructose-programmed astrocytic glycolysis and oxidative phosphorylation of female rat offspring

    Wu, C., Hung, C., Hirase, Hajime, Tain, Y., Lee, W., Chan, J. Y. H., Fu, M., Chen, L., Liu, W., Liang, C., Ho, Y., Kung, Y. C., Leu, S. & Wu, K. L. H., 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 4, p. E622-E634

    Research output: Contribution to journalJournal articleResearchpeer-review