Center for Translational Neuromedicine

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  1. Published

    Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization

    Monai, H., Koketsu, S., Shinohara, Y., Ueki, T., Kusk, P., Hauglund, Natalie Linea, Samson, A. J., Nedergaard, Maiken & Hirase, Hajime, 2021, In: Scientific Reports. 11, 1, 8150.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke

    Monai, H., Wang, X., Yahagi, K., Lou, N., Mestre, H., Xu, Q., Abe, Y., Yasui, M., Iwai, Y., Nedergaard, Maiken & Hirase, Hajime, 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 22, p. 11010-11019 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Impact of Global Mean Normalization on Regional Glucose Metabolism in the Human Brain

    Mortensen, K. N., Gjedde, Albert, Thompson, G. J., Herman, P., Parent, M. J., Rothman, D. L., Kupers, Ron, Ptito, Maurice, Stender, J., Laureys, S., Riedl, V., Alkire, M. T. & Hyder, F., 2018, In: Neural Plasticity. 2018, 16 p., 6120925.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    PDGF-B Is Required for Development of the Glymphatic System

    Munk, A. S., Wang, W., Bèchet, N. B., Eltanahy, A. M., Cheng, A. X., Sigurdsson, B., Benraiss, A., Mäe, M. A., Kress, B. T., Kelley, D. H., Betsholtz, C., Møllgård, Kjeld, Meissner, A., Nedergaard, Maiken & Lundgaard, I., 2019, In: Cell Reports. 26, 11, p. 2955-2969.e3 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A mesothelium divides the subarachnoid space into functional compartments

    Møllgård, Kjeld, Beinlich, Felix Ralf Michael, Kusk, P., Miyakoshi, L. M., Delle, Christine, Pla Requena, Virginia Teresa, Hauglund, Natalie Linea, Esmail, Tina, Rasmussen, Martin Kaag, Gomolka, Ryszard Stefan, Mori, Yuki & Nedergaard, Maiken, 2023, In: Science. 379, 6627, p. 84-885

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Lactate biosensors for spectrally and spatially multiplexed fluorescence imaging

    Nasu, Y., Aggarwal, A., Le, G. N. T., Vo, C. T., Kambe, Y., Wang, X., Beinlich, F. R. M., Lee, A. B., Ram, T. R., Wang, F., Gorzo, K. A., Kamijo, Y., Boisvert, M., Nishinami, S., Kawamura, G., Ozawa, T., Toda, H., Gordon, G. R., Ge, S., Hirase, H. & 5 others, Nedergaard, Maiken, Paquet, M. E., Drobizhev, M., Podgorski, K. & Campbell, R. E., 2023, In: Nature Communications. 14, 1, 17 p., 6598.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Secondary brain stem hemorrhage in stroke

    Nedergaard, Maiken, Klinken, L. & Paulson, Olaf B., 1 Jul 1983, In: Stroke. 14, 4, p. 501-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The glymphatic system: reactive gliosis as a negative regulator

    Nedergaard, Maiken, 2019, In: Glia. 67, S1, p. E91 1 p., S26-02.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  9. Published

    Glymphatic failure as a final common pathway to dementia

    Nedergaard, Maiken & Goldman, Steven Alan, 2020, In: Science (New York, N.Y.). 370, 6512, p. 50-56 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Modeling the Mutational and Phenotypic Landscapes of Pelizaeus-Merzbacher Disease with Human iPSC-Derived Oligodendrocytes

    Nevin, Z. S., Factor, D. C., Karl, R. T., Douvaras, P., Laukka, J., Windrem, M. S., Goldman, Steven Alan, Fossati, V., Hobson, G. M. & Tesar, P. J., 6 Apr 2017, In: American Journal of Human Genetics. 100, 4, p. 617-634 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Physiological Mechanisms and Significance of Intracranial B Waves

    Newell, D. W., Nedergaard, Maiken & Aaslid, R., 2022, In: Frontiers in Neurology. 13, 13 p., 872701.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Defining novel functions for cerebrospinal fluid in ALS pathophysiology

    Ng Kee Kwong, K. C., Mehta, A. R., Nedergaard, Maiken & Chandran, S., 2020, In: Acta Neuropathologica Communications. 8, 1, 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Direct conversion of hESC-derived glial progenitors into midbrain dopaminergic neurons

    Nolbrant, S., Hoban, D., Giacomoni, J., Ottosson, D. R., Goldman, Steven Alan & Parmar, M., 2019, In: Glia. 67, S1, p. E662-E663 2 p., T16-015B.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  14. Published

    Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons

    Nolbrant, S., Giacomoni, J., Hoban, D. B., Bruzelius, A., Birtele, M., Chandler-Militello, D., Pereira, M., Ottosson, D. R., Goldman, Steven Alan & Parmar, M., 2020, In: Stem Cell Reports. 15, 4, p. 869-882 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Impaired Glymphatic Transport in Spontaneously Hypertensive Rats

    Nygaard Mortensen, K., Sanggaard, S., Mestre, H., Lee, H., Kostrikov, S., L R Xavier, Anna , Gjedde, Albert, Benveniste, H. & Nedergaard, Maiken, 2019, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 32, p. 6365-6377 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain?

    Oberheim Bush, N. A. & Nedergaard, Maiken, Sep 2017, In: Neurochemical Research. 42, 9, p. 2577-2587 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance

    Oe, Y., Wang, Xiaowen, Patriarchi, T., Konno, A., Ozawa, K., Yahagi, K., Hirai, H., Tian, L., McHugh, T. J. & Hirase, Hajime, 2020, In: Nature Communications. 11, 1, 15 p., 471.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Supplements with different ruminal undegradable protein levels for dairy heifers in tropical pasture: intake, digestibility and plasma urea nitrogen

    Oliveira, R., Pereira, J., Vieira, R., do Nascimento, D., Pacheco, B., Ribeiro, M. & Leonel, F., 2003, PROGRESS IN RESEARCH ON ENERGY AND PROTEIN METABOLISM. Souffrant, WB. & Metges, CC. (eds.). Wageningen Academic Publishers, p. 635-639 5 p. (EAAP EUROPEAN ASSOCIATION FOR ANIMAL PRODUCTION PUBLICATION).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  19. Published

    Human ESC-Derived Chimeric Mouse Models of Huntington's Disease Reveal Cell-Intrinsic Defects in Glial Progenitor Cell Differentiation

    Osipovitch, M., Martinez, A. A., Mariani, J. N., Cornwell, A., Dhaliwal, S., Zou, L., Chandler-Militello, D., Wang, S., Li, X., Benraiss, S., Agate, R., Lampp, A., Benraiss, A., Windrem, M. S. & Goldman, Steven Alan, 2019, In: Cell Stem Cell. 24, 1, p. 107-122.e7

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The intrinsic effects of EIF2B mutations in human Vanishing White Matter-derived glial progenitor cells

    Osorio, M. J., Lassen, Mette, Kristine, M. & Goldman, Steven Alan, 2019, In: Glia. 67, S1, p. E312-E313 2 p., T08-031A.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  21. Published

    Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease

    Osorio, M. J., Rowitch, D. H., Tesar, P., Wernig, M., Windrem, M. S. & Goldman, Steven Alan, Feb 2017, In: Stem Cells. 35, 2, p. 311-315 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Glial progenitor cells of the adult human white and grey matter are contextually distinct

    Osorio, M. J., Mariani, J. N., Zou, L., Schanz, S. J., Heffernan, K., Cornwell, A. & Goldman, Steven Alan, 2023, In: Glia. 71, 3, p. 524-540 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Glial progenitor cell-based treatment of the childhood leukodystrophies

    Osório, M. J. & Goldman, Steven Alan, Sep 2016, In: Experimental Neurology. 283, Part B, p. 476-488 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Astrocytic GPCR-Induced Ca2+ Signaling Is Not Causally Related to Local Cerebral Blood Flow Changes

    Ozawa, K., Nagao, Masaki, Konno, A., Iwai, Y., Vittani, Marta, Kusk, P., Mishima, Tsuneko, Hirai, H., Nedergaard, Maiken & Hirase, Hajime, 2023, In: International Journal of Molecular Sciences. 24, 17, 12 p., 13590.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Lung megakaryocytes are immune modulatory cells

    Pariser, D. N., Hilt, Z. T., Ture, S. K., Blick-Nitko, S. K., Looney, M. R., Cleary, S. J., Roman-Pagan, E., Saunders, J., Georas, S. N., Veazey, J., Madere, F., Santos, L. T., Arne, A., Huynh, N. P. T., Livada, A. C., Guerrero-Martin, S. M., Lyons, C., Metcalf-Pate, K. A., McGrath, K. E., Palis, J. & 1 others, Morrell, C. N., 2021, In: Journal of Clinical Investigation. 131, 1, e137377.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Human iPSC-derived neural precursor cells differentiate into multiple cell types to delay disease progression following transplantation into YAC128 Huntington's disease mouse model

    Park, H. J., Jeon, J., Choi, J., Kim, J. Y., Kim, H. S., Huh, J. Y., Goldman, Steven Alan & Song, J., 2021, In: Cell Proliferation. 54, 8, 16 p., e13082.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Changes in visual processing during progression of Tau accumulation and neurodegeneration in a mouse model of human tauopathy

    Parka, A., Nedergaard, Maiken, Sotty, F. & Laursen, B., 2021, In: Investigative Ophthalmology & Visual Science. 62, 8, 3 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  28. Published

    Visual Evoked Potentials as an Early-Stage Biomarker in the rTg4510 Tauopathy Mouse Model

    Parka, A., Volbracht, C., Hall, B., Bastlund, J. F., Nedergaard, Maiken, Laursen, B., Botta, P. & Sotty, F., 2023, In: Journal of Alzheimer's Disease. 93, 1, p. 247-262 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model

    Parka, A., Degel, C., Dreyer, J., Richter, U., Hall, B., Bastlund, J. F., Laursen, B., Nedergaard, Maiken, Sotty, F. & Botta, P., 2023, In: Neurobiology of Disease. 178, 13 p., 106012.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Single-nucleus expression characterization of non-enhancing region of recurrent high-grade glioma

    Patel, K. S., Tessema, K. K., Kawaguchi, R., Dudley, L., Alvarado, A. G., Muthukrishnan, S. D., Perryman, T., Hagiwara, A., Swarup, V., Liau, L. M., Wang, A. C., Yong, W., Geschwind, D. H., Nakano, I., Goldman, Steven Alan, Everson, R. G., Ellingson, B. M. & Kornblum, H. I., 2024, In: Neuro-Oncology Advances. 6, 1, 14 p., vdae005.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    DNase treatment prevents CSF block in early experimental pneumococcal meningitis

    Pavan, C., L R Xavier, Anna , Ramos, M., Fisher, J., Kritsilis, M., Linder, A., Bentzer, P., Nedergaard, Maiken & Lundgaard, I., 2021, In: Annals of Neurology. 90, 4, p. 653-669 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    SpAD Biofunctionalized Cellulose Acetate Scaffolds Inhibit Staphylococcus aureus Adherence in a Coordinating Function with the von Willebrand A1 Domain (vWF A1)

    Pendas, S., Asiminas, Antonios, Katranidis, A., Tsioptsias, C., Pitou, M., Papadopoulos, G. & Choli-Papadopoulou, T., 2022, In: Journal of Functional Biomaterials. 13, 17 p., 21.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Could dexmedetomidine be repurposed as a glymphatic enhancer?

    Persson, N. D. Å., Uusalo, P., Nedergaard, Maiken, Lohela, T. J. & Lilius, T. O., 2022, In: Trends in Pharmacological Sciences. 43, 12, p. 1030-1040 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    An unnoticed player overseeing CSF flux

    Pla Requena, Virginia Teresa & Nedergaard, Maiken, 2022, In: Nature Cardiovascular Research. 1, 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  35. Published

    Structural characterization of SLYM—a 4th meningeal membrane

    Pla Requena, Virginia Teresa, Bitsika, S., Giannetto, M. J., Ladron-de-Guevara, A., Gahn-Martinez, D., Mori, Yuki, Nedergaard, Maiken & Møllgård, Kjeld, 2023, In: Fluids and Barriers of the CNS. 20, 1, 18 p., 93.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    A real-time in vivo clearance assay for quantification of glymphatic efflux

    Plá, V., Bork, Peter Aleksander Rousing, Harnpramukkul, A., Olveda, G., Ladrón-de-Guevara, A., Giannetto, M. J., Hussain, R., Wang, W., Kelley, D. H., Hablitz, L. M. & Nedergaard, Maiken, 2022, In: Cell Reports. 40, 11, 20 p., 111320.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection

    Raghunandan, A., Ladron-De-guevara, A., Tithof, J., Mestre, H., Du, T., Nedergaard, Maiken, Thomas, J. H. & Kelley, D. H., 2021, In: eLife. 10, 15 p., e65958.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Single cell mapping the evolution of the spatial processing centre within the brain

    Ralbovszki, Dorottya Maria, Bertelsen, Mads Frost, Buchmann, Kurt, Mori, Yuki, Gorodkin, Jan, Hemberg, M., Seemann, Ernst Stefan, Khodosevich, Konstantin & Hall, Vanessa Jane, 1 May 2022.

    Research output: Contribution to conference › Poster › Communication

  39. Published

    Cisterna magna injection in rats to study glymphatic function

    Ramos, M., Burdon Bechet, N., Battistella, R., Pavan, C., L R Xavier, Anna , Nedergaard, Maiken & Lundgaard, I., 2019, Astrocytes: Methods and Protocols. Di Benedetto, B. (ed.). Humana Press, p. 97-104 8 p. (Methods in Molecular Biology, Vol. 1938).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  40. Published

    Twists and turns of ocular glymphatic clearance – new study reveals surprising findings in glaucoma

    Rangroo Thrane, V., Hynnekleiv, L., Wang, X., Thrane, A. S., Krohn, J. & Nedergaard, Maiken, 2021, In: Acta Ophthalmologica. 99, 2, p. e283-e284 2 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  41. Published

    Revisiting Risk-stratified Whiplash-exposed Patients 12 to 14 Years after Injury

    Rasmussen, Martin Kaag, Kongsted, A., Carstensen, T., Jensen, T. S. & Kasch, H., 2020, In: Clinical Journal of Pain. 36, 12, p. 923-931 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The glymphatic pathway in neurological disorders

    Rasmussen, Martin Kaag, Mestre, H. & Nedergaard, Maiken, 2018, In: The Lancet Neurology. 17, 11, p. 1016-1024 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    Fluid Transport in the Brain

    Rasmussen, Martin Kaag, Mestre, H. & Nedergaard, Maiken, 2022, In: Physiological Reviews. 102, p. 1025-1151 27 p.

    Research output: Contribution to journal › Review › Research › peer-review

  44. Published

    Interstitial ions: A key regulator of state-dependent neural activity?

    Rasmussen, R., O'Donnell, J., Ding, F. & Nedergaard, Maiken, 2020, In: Progress in Neurobiology. 98, 101802.

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    Cortex-wide Changes in Extracellular Potassium Ions Parallel Brain State Transitions in Awake Behaving Mice

    Rasmussen, R., Nicholas, E., Petersen, Nicolas Caesar, Dietz, Andrea Grostøl, Xu, Q., Sun, Q. & Nedergaard, Maiken, 2019, In: Cell Reports. 28, 5, p. 1182-1194 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Spontaneous Functional Recovery from Incomplete Spinal Cord Injury

    Rasmussen, R. & Carlsen, Eva Maria Meier, 17 Aug 2016, In: The Journal of Neuroscience. 36, 33, p. 8535-8537 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  47. Published

    Astrocytes: Tailored to Support the Demand of Neural Circuits?

    Rasmussen, R. & Samson, A. J., 27 Sep 2017, In: Cell Systems. 5, 3, p. 165-167 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Astrocytes: integrators of arousal state and sensory context

    Rasmussen, R. N., Asiminas, Antonios, Carlsen, Eva Maria Meier, Kjærby, Celia & Smith, N. A., 2023, In: Trends in Neurosciences. 46, 6, 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    The elusive varicose astrocytes

    Rasmussen, R. N. & Smith, N. A., 2022, In: Trends in Neurosciences. 45, 2, p. 94-95 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  50. Published

    An in vivo Pig Model for Testing Novel Positron Emission Tomography Radioligands Targeting Cerebral Protein Aggregates

    Raval, N. R., Nasser, A., Madsen, C. A., Beschorner, Natalie, Beaman, Emily Eufaula, Juhl, M., Lehel, S., Palner, M., Svarer, C., Plavén-Sigray, P., Jørgensen, Louise Møller & Knudsen, Gitte Moos, 2022, In: Frontiers in Neuroscience. 16, 12 p., 847074.

    Research output: Contribution to journal › Journal article › Research › peer-review

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