Hajime Hirase
Professor
Center for Translational Neuromedicine
Blegdamsvej 3B
2200 København N
A Rationally and Computationally Designed Fluorescent Biosensor for d -Serine
Vongsouthi, V., Whitfield, J. H., Unichenko, P., Mitchell, J. A., Breithausen, B., Khersonsky, O., Kremers, L., Janovjak, H., Monai, H., Hirase, Hajime, Fleishman, S. J., Henneberger, C. & Jackson, C. J., 2021, In: ACS Sensors. 6, 11, p. 4193-4205 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A community-based transcriptomics classification and nomenclature of neocortical cell types
Yuste, R., Hawrylycz, M., Aalling, N., Aguilar-valles, A., Arendt, D., Arnedillo, R. A., Ascoli, G. A., Bielza, C., Bokharaie, V., Bergmann, T. B., Bystron, I., Capogna, M., Chang, Y., Clemens, A., De Kock, C. P. J., Defelipe, J., Dos Santos, S. E., Dunville, K., Feldmeyer, D., Fiáth, R. & 53 others, , 2020, In: Nature Neuroscience. 23, p. 1456-1468 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A sensitive and specific genetically-encoded potassium ion biosensor for in vivo applications across the tree of life
Wu, S-Y., Wen, Y., Serre, N. B. C., Laursen, C. C. H., Dietz, A. G., Taylor, B. R., Drobizhev, M., Molina, R. S., Aggarwal, A., Rancic, V., Becker, M., Ballanyi, K., Podgorski, K., Hirase, H., Nedergaard, M., Fendrych, M., Lemieux, M. J., Eberl, D. F., Kay, A. R., Campbell, R. E. & 1 others, , 2023, In: PLOS Biology. 20, 9, 23 p., e3001772.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A three-dimensional, population-based average of the C57BL/6 mouse brain from DAPI-stained coronal slices
Stæger, Frederik Filip Vinggaard, Mortensen, K. N., Nielsen, M. S. N., Sigurdsson, B., Kaufmann, L. K., Hirase, Hajime & Nedergaard, Maiken, 2020, In: Scientific Data. 7, 1, 7 p., 235.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization
Monai, H., Koketsu, S., Shinohara, Y., Ueki, T., Kusk, P., Hauglund, Natalie Linea, Samson, A. J., Nedergaard, Maiken & Hirase, Hajime, 2021, In: Scientific Reports. 11, 1, 8150.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke
Monai, H., Wang, X., Yahagi, K., Lou, N., Mestre, H., Xu, Q., Abe, Y., Yasui, M., Iwai, Y., Nedergaard, Maiken & Hirase, Hajime, 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 22, p. 11010-11019 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Anxiety control by astrocytes in the lateral habenula
Tan, W., Ikoma, Y., Takahashi, Y., Konno, A., Hirai, H., Hirase, Hajime & Matsui, K., 2024, (E-pub ahead of print) In: Neuroscience Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aquaporin-4-dependent glymphatic solute transport in the rodent brain
Mestre, H., Hablitz, L. M., Xavier, A. L. R., Feng, W., Zou, W., Pu, T., Monai, H., Murlidharan, G., Rivera, R. M. C., Simon, M. J., Pike, M. M., Pla, V., Du, T., Kress, B. T., Wang, X., Plog, B. A., Thrane, A. S., Lundgaard, I., Abe, Y., Yasui, M. & 6 others, , 2018, In: eLife. 7, 31 p., :e40070.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of astrocytes as a mediator of memory and learning in rodents
Akther, S. & Hirase, Hajime, 2022, In: Glia. 70, 8, p. 1484-1505 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Astrocytic GPCR-Induced Ca2+ Signaling Is Not Causally Related to Local Cerebral Blood Flow Changes
Ozawa, K., Nagao, Masaki, Konno, A., Iwai, Y., Vittani, Marta, Kusk, P., Mishima, Tsuneko, Hirai, H., Nedergaard, Maiken & Hirase, Hajime, 2023, In: International Journal of Molecular Sciences. 24, 17, 12 p., 13590.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Astrocytic chloride is brain state dependent and modulates inhibitory neurotransmission in mice
Untiet, Verena, Beinlich, Felix Ralf Michael, Kusk, P., Kang, N., Ladrón-de-Guevara, A., Song, W., Kjærby, Celia, Andersen, Mie, Hauglund, Natalie Linea, Bojarowska, Zuzanna, Sigurdsson, B., Deng, S., Hirase, Hajime, Petersen, Nicolas Caesar, Verkhratsky, A. & Nedergaard, Maiken, 2023, In: Nature Communications. 14, 1, 14 p., 1871.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brain-specific glycosylation of protein tyrosine phosphatase receptor type Z (PTPRZ) marks a demyelination-associated astrocyte subtype
Takahashi, K., Kanekiyo, K., Sakuda, K., Muto, Y., Iguchi, M., Matsuda, N., Hashimoto, Y., Kanai, K., Ogawa, H., Hirase, Hajime, Kakita, A., Bizen, N., Takebayashi, H., Kawaguchi, Y., Uzuki, M. & Kitazume, S., 2023, In: Journal of Neurochemistry. 166, 3, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Butyrate reduction and HDAC4 increase underlie maternal high fructose-induced metabolic dysfunction in hippocampal astrocytes in female rats
Wu, K. L. H., Liu, W. C., Wu, C. W., Fu, M. H., Huang, H. M., Tain, Y. L., Liang, C. K., Hung, C. Y., Chen, I. C., Hung, P. L., Lin, Y. J. & Hirase, Hajime, 2024, In: Journal of Nutritional Biochemistry. 126, 14 p., 109571.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebrospinal fluid influx drives acute ischemic tissue swelling
Mestre, H., Du, T., Sweeney, A. M., Liu, G., Samson, A. J., Peng, W., Mortensen, K. N., Stæger, F. F., Bork, P. A. R., Bashford, L., Toro, E. R., Tithof, J., Kelley, D. H., Thomas, J. H., Hjorth, P. G., Martens, E. A., Mehta, R. I., Solis, O., Blinder, P., Kleinfeld, D. & 3 others, , 2020, In: Science. 367, 6483, 8 p., eaaw7462.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebrospinal fluid is a significant fluid source for anoxic cerebral oedema
Du, T., Mestre, H., Kress, B. T., Liu, G., Sweeney, A. M., Samson, A. J., Rasmussen, M. K., Mortensen, K. N., Bork, P. A. R., Peng, W., Olveda, G. E., Bashford, L., Toro, E. R., Tithof, J., Kelley, D. H., Thomas, J. H., Hjorth, P. G., Martens, E. A., Mehta, R. I., Hirase, H. & 2 others, , 2022, In: Brain. 145, 2, p. 787–797 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Depth-targeted intracortical microstroke by two-photon photothrombosis in rodent brain
Fukuda, M., Matsumura, T., Suda, T. & Hirase, Hajime, 2022, In: Neurophotonics. 9, 2, 9 p., 021910.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance
Oe, Y., Wang, Xiaowen, Patriarchi, T., Konno, A., Ozawa, K., Yahagi, K., Hirai, H., Tian, L., McHugh, T. J. & Hirase, Hajime, 2020, In: Nature Communications. 11, 1, 15 p., 471.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamic fluctuations of the locus coeruleus-norepinephrine system underlie sleep state transitions
Kjærby, Celia, Andersen, Mie, Hauglund, Natalie Linea, Ding, F., Wang, W., Xu, Q., Deng, S., Kang, N., Peng, S., Sun, Q., Dall, C., Jørgensen, P. K., Feng, J., Li, Y., Weikop, Pia, Hirase, Hajime & Nedergaard, Maiken, 2 Sep 2020, 1 p.Research output: Other contribution › Research
- Published
Editorial: Role of Astrocytes in Seizures Induced by Traumatic Brain Injury
Wang, F., Pan, F., Hirase, Hajime & Huang, J. H., 2020, In: Frontiers in Neurology. 11, 604788.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Glycogen distribution in mouse hippocampus
Hirase, Hajime, Akther, S., Wang, X. & Oe, Y., 2019, In: Journal of Neuroscience Research. 97, 8, p. 923-932 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lactate biosensors for spectrally and spatially multiplexed fluorescence imaging
Nasu, Y., Aggarwal, A., Le, G. N. T., Vo, C. T., Kambe, Y., Wang, X., Beinlich, F. R. M., Lee, A. B., Ram, T. R., Wang, F., Gorzo, K. A., Kamijo, Y., Boisvert, M., Nishinami, S., Kawamura, G., Ozawa, T., Toda, H., Gordon, G. R., Ge, S., Hirase, H. & 5 others, , 2023, In: Nature Communications. 14, 1, 17 p., 6598.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liver-secreted fluorescent blood plasma markers enable chronic imaging of the microcirculation
Wang, Xiaowen, Delle, Christine, Asiminas, Antonios, Akther, S., Vittani, Marta, Brøgger, Peter, Kusk, P., Vo, C. T., Radovanovic, Tessa, Konno, A., Hirai, H., Fukuda, M., Weikop, Pia, Goldman, Steven Alan, Nedergaard, Maiken & Hirase, Hajime, 2022, In: Cell Reports Methods. 2, 10, 16 p., 100302.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Local extracellular K+ in cortex regulates norepinephrine levels, network state, and behavioral output
Dietz, Andrea Grostøl, Weikop, Pia, Hauglund, Natalie Linea, Andersen, Mie, Petersen, Nicolas Caesar, Rose, Laura, Hirase, Hajime & Nedergaard, Maiken, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 40, 9 p., e2305071120.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Locomotion Induces Fundamentally Different Patterns of Ca2+Signaling in Astrocytes and Neurons
Hirase, Hajime & Nedergaard, Maiken, 2023, In: Function. 4, 4, 2 p., zqad028.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine
Kjærby, Celia, Andersen, Mie, Hauglund, Natalie Linea, Untiet, Verena, Dall, C., Sigurdsson, B., Ding, F., Feng, J., Li, Y., Weikop, Pia, Hirase, Hajime & Nedergaard, Maiken, 2022, In: Nature Neuroscience. 25, p. 1059–1070 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 215672745
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Aquaporin-4-dependent glymphatic solute transport in the rodent brain
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
100
downloads
Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
96
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Transcranial Direct Current Stimulation (tDCS Induces Adrenergic Receptor-Dependent Microglial Morphological Changes in Mice
Research output: Contribution to journal › Journal article › Research › peer-review
Published